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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WDR48
Full Name:
WD repeat-containing protein 48
Alias:
KIAA1449; P80; USP1-associated factor 1; WD repeat domain 48; WD repeat endosomal protein
Type:
Vesicle protein
Mass (Da):
76210
Number AA:
677
UniProt ID:
Q8TAF3
International Prot ID:
IPI00658210
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005764
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0044419
GO:0019941
GO:0016579
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
A
A
H
H
R
Q
N
T
A
G
R
R
K
V
Q
Site 2
S18
G
R
R
K
V
Q
V
S
Y
V
I
R
D
E
V
Site 3
Y19
R
R
K
V
Q
V
S
Y
V
I
R
D
E
V
E
Site 4
Y28
I
R
D
E
V
E
K
Y
N
R
N
G
V
N
A
Site 5
Y67
N
Q
H
K
Q
D
P
Y
I
A
S
M
E
H
H
Site 6
S92
C
N
G
K
T
L
I
S
A
S
S
D
T
T
V
Site 7
S95
K
T
L
I
S
A
S
S
D
T
T
V
K
V
W
Site 8
T98
I
S
A
S
S
D
T
T
V
K
V
W
N
A
H
Site 9
T115
F
C
M
S
T
L
R
T
H
K
D
Y
V
K
A
Site 10
Y119
T
L
R
T
H
K
D
Y
V
K
A
L
A
Y
A
Site 11
S134
K
D
K
E
L
V
A
S
A
G
L
D
R
Q
I
Site 12
T158
A
L
T
A
S
N
N
T
V
T
T
S
S
L
S
Site 13
T160
T
A
S
N
N
T
V
T
T
S
S
L
S
G
N
Site 14
T161
A
S
N
N
T
V
T
T
S
S
L
S
G
N
K
Site 15
S163
N
N
T
V
T
T
S
S
L
S
G
N
K
D
S
Site 16
S165
T
V
T
T
S
S
L
S
G
N
K
D
S
I
Y
Site 17
S170
S
L
S
G
N
K
D
S
I
Y
S
L
A
M
N
Site 18
Y172
S
G
N
K
D
S
I
Y
S
L
A
M
N
Q
L
Site 19
S173
G
N
K
D
S
I
Y
S
L
A
M
N
Q
L
G
Site 20
T199
L
R
V
W
D
P
R
T
C
A
K
L
M
K
L
Site 21
T223
L
L
L
N
R
D
G
T
Q
C
L
S
G
S
S
Site 22
S227
R
D
G
T
Q
C
L
S
G
S
S
D
G
T
I
Site 23
T233
L
S
G
S
S
D
G
T
I
R
L
W
S
L
G
Site 24
S238
D
G
T
I
R
L
W
S
L
G
Q
Q
R
C
I
Site 25
T247
G
Q
Q
R
C
I
A
T
Y
R
V
H
D
E
G
Site 26
Y248
Q
Q
R
C
I
A
T
Y
R
V
H
D
E
G
V
Site 27
T265
L
Q
V
N
D
A
F
T
H
V
Y
S
G
G
R
Site 28
Y277
G
G
R
D
R
K
I
Y
C
T
D
L
R
N
P
Site 29
T279
R
D
R
K
I
Y
C
T
D
L
R
N
P
D
I
Site 30
S305
L
K
M
E
L
D
R
S
A
D
P
P
P
A
I
Site 31
S335
G
I
H
N
F
R
A
S
G
D
Y
D
N
D
C
Site 32
Y338
N
F
R
A
S
G
D
Y
D
N
D
C
T
N
P
Site 33
T347
N
D
C
T
N
P
I
T
P
L
C
T
Q
P
D
Site 34
T377
N
D
K
R
H
I
L
T
K
D
T
N
N
N
V
Site 35
Y386
D
T
N
N
N
V
A
Y
W
D
V
L
K
A
C
Site 36
Y415
K
K
R
F
K
M
V
Y
V
P
N
W
F
S
V
Site 37
S451
S
A
K
D
A
G
F
S
S
P
D
G
S
D
P
Site 38
S452
A
K
D
A
G
F
S
S
P
D
G
S
D
P
K
Site 39
S456
G
F
S
S
P
D
G
S
D
P
K
L
N
L
G
Site 40
Y506
R
V
Q
K
G
N
G
Y
F
Q
V
P
P
H
T
Site 41
S533
F
R
L
L
C
R
D
S
G
G
E
T
E
S
M
Site 42
T537
C
R
D
S
G
G
E
T
E
S
M
L
L
N
E
Site 43
T545
E
S
M
L
L
N
E
T
V
P
Q
W
V
I
D
Site 44
Y568
K
F
N
K
I
P
F
Y
L
Q
P
H
A
S
S
Site 45
S574
F
Y
L
Q
P
H
A
S
S
G
A
K
T
L
K
Site 46
T579
H
A
S
S
G
A
K
T
L
K
K
D
R
L
S
Site 47
S586
T
L
K
K
D
R
L
S
A
S
D
M
L
Q
V
Site 48
S588
K
K
D
R
L
S
A
S
D
M
L
Q
V
R
K
Site 49
Y601
R
K
V
M
E
H
V
Y
E
K
I
I
N
L
D
Site 50
S611
I
I
N
L
D
N
E
S
Q
T
T
S
S
S
N
Site 51
T613
N
L
D
N
E
S
Q
T
T
S
S
S
N
N
E
Site 52
T614
L
D
N
E
S
Q
T
T
S
S
S
N
N
E
K
Site 53
S615
D
N
E
S
Q
T
T
S
S
S
N
N
E
K
P
Site 54
S617
E
S
Q
T
T
S
S
S
N
N
E
K
P
G
E
Site 55
T669
W
K
S
G
G
D
L
T
L
H
Y
R
Q
K
S
Site 56
Y672
G
G
D
L
T
L
H
Y
R
Q
K
S
T
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation