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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EXOC6
Full Name:
Exocyst complex component 6
Alias:
Exocyst complex component Sec15A;SEC15-like protein 1
Type:
Mass (Da):
93722
Number AA:
804
UniProt ID:
Q8TAG9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
E
N
S
E
S
L
G
T
V
P
E
H
Site 2
T10
E
N
S
E
S
L
G
T
V
P
E
H
E
R
I
Site 3
S23
R
I
L
Q
E
I
E
S
T
D
T
A
C
V
G
Site 4
T26
Q
E
I
E
S
T
D
T
A
C
V
G
P
T
L
Site 5
T32
D
T
A
C
V
G
P
T
L
R
S
V
Y
D
D
Site 6
S35
C
V
G
P
T
L
R
S
V
Y
D
D
Q
P
N
Site 7
Y37
G
P
T
L
R
S
V
Y
D
D
Q
P
N
A
H
Site 8
T97
L
K
V
Q
V
T
D
T
N
R
R
F
Q
D
A
Site 9
T126
R
I
Q
Q
R
N
I
T
T
V
V
E
K
L
Q
Site 10
S150
S
K
L
K
E
Q
M
S
A
K
R
Y
Y
S
A
Site 11
Y154
E
Q
M
S
A
K
R
Y
Y
S
A
L
K
T
M
Site 12
Y155
Q
M
S
A
K
R
Y
Y
S
A
L
K
T
M
E
Site 13
S156
M
S
A
K
R
Y
Y
S
A
L
K
T
M
E
Q
Site 14
T160
R
Y
Y
S
A
L
K
T
M
E
Q
L
E
N
V
Site 15
Y168
M
E
Q
L
E
N
V
Y
F
P
W
V
S
Q
Y
Site 16
Y175
Y
F
P
W
V
S
Q
Y
R
F
C
Q
L
M
I
Site 17
S196
R
E
D
I
K
E
I
S
M
S
D
L
K
D
F
Site 18
S198
D
I
K
E
I
S
M
S
D
L
K
D
F
L
E
Site 19
S206
D
L
K
D
F
L
E
S
I
R
K
H
S
D
K
Site 20
S211
L
E
S
I
R
K
H
S
D
K
I
G
E
T
A
Site 21
T227
K
Q
A
Q
H
Q
K
T
F
S
V
S
L
Q
K
Site 22
S229
A
Q
H
Q
K
T
F
S
V
S
L
Q
K
Q
N
Site 23
Y245
M
K
F
G
K
N
M
Y
I
N
R
D
R
I
P
Site 24
T258
I
P
E
E
R
N
E
T
V
L
K
H
S
L
E
Site 25
T276
E
N
E
E
E
I
L
T
V
Q
D
L
V
D
F
Site 26
Y293
V
Y
R
C
L
H
I
Y
S
V
L
G
D
E
E
Site 27
T301
S
V
L
G
D
E
E
T
F
E
N
Y
Y
R
K
Site 28
Y305
D
E
E
T
F
E
N
Y
Y
R
K
Q
R
K
K
Site 29
S322
R
L
V
L
Q
P
Q
S
N
M
H
E
T
V
D
Site 30
T327
P
Q
S
N
M
H
E
T
V
D
G
Y
R
R
Y
Site 31
Y331
M
H
E
T
V
D
G
Y
R
R
Y
F
T
Q
I
Site 32
Y334
T
V
D
G
Y
R
R
Y
F
T
Q
I
V
G
F
Site 33
Y360
Q
G
L
V
T
R
A
Y
T
D
E
L
W
N
M
Site 34
T361
G
L
V
T
R
A
Y
T
D
E
L
W
N
M
A
Site 35
S380
I
A
V
L
R
A
H
S
S
Y
C
T
D
P
D
Site 36
S381
A
V
L
R
A
H
S
S
Y
C
T
D
P
D
L
Site 37
Y382
V
L
R
A
H
S
S
Y
C
T
D
P
D
L
V
Site 38
T384
R
A
H
S
S
Y
C
T
D
P
D
L
V
L
E
Site 39
Y406
F
A
D
T
L
Q
G
Y
G
F
P
V
N
R
L
Site 40
Y424
L
F
E
I
R
D
Q
Y
N
E
T
L
L
K
K
Site 41
Y445
D
I
F
E
E
D
N
Y
S
P
I
P
V
V
N
Site 42
S446
I
F
E
E
D
N
Y
S
P
I
P
V
V
N
E
Site 43
Y456
P
V
V
N
E
E
E
Y
K
I
V
I
S
K
F
Site 44
S474
D
P
D
L
E
K
Q
S
F
P
K
K
F
P
M
Site 45
S482
F
P
K
K
F
P
M
S
Q
S
V
P
H
I
Y
Site 46
S503
I
Y
A
S
L
K
F
S
E
S
L
H
R
S
S
Site 47
S505
A
S
L
K
F
S
E
S
L
H
R
S
S
T
E
Site 48
S509
F
S
E
S
L
H
R
S
S
T
E
I
D
D
M
Site 49
S510
S
E
S
L
H
R
S
S
T
E
I
D
D
M
L
Site 50
T511
E
S
L
H
R
S
S
T
E
I
D
D
M
L
R
Site 51
S520
I
D
D
M
L
R
K
S
T
N
L
L
L
T
R
Site 52
T521
D
D
M
L
R
K
S
T
N
L
L
L
T
R
T
Site 53
Y563
H
L
E
Q
A
C
K
Y
L
E
D
F
I
T
N
Site 54
S575
I
T
N
I
T
N
I
S
Q
E
T
V
H
T
T
Site 55
T581
I
S
Q
E
T
V
H
T
T
R
L
Y
G
L
S
Site 56
Y585
T
V
H
T
T
R
L
Y
G
L
S
T
F
K
D
Site 57
S588
T
T
R
L
Y
G
L
S
T
F
K
D
A
R
H
Site 58
T589
T
R
L
Y
G
L
S
T
F
K
D
A
R
H
A
Site 59
Y602
H
A
A
E
G
E
I
Y
T
K
L
N
Q
K
I
Site 60
Y618
E
F
V
Q
L
A
D
Y
D
W
T
M
S
E
P
Site 61
T621
Q
L
A
D
Y
D
W
T
M
S
E
P
D
G
R
Site 62
S623
A
D
Y
D
W
T
M
S
E
P
D
G
R
A
S
Site 63
S630
S
E
P
D
G
R
A
S
G
Y
L
M
D
L
I
Site 64
Y632
P
D
G
R
A
S
G
Y
L
M
D
L
I
N
F
Site 65
S703
Q
C
E
L
F
A
S
S
E
P
V
P
G
F
Q
Site 66
Y740
W
S
T
Y
L
A
D
Y
G
Q
P
A
S
K
Y
Site 67
S745
A
D
Y
G
Q
P
A
S
K
Y
L
R
V
N
P
Site 68
Y747
Y
G
Q
P
A
S
K
Y
L
R
V
N
P
N
T
Site 69
T754
Y
L
R
V
N
P
N
T
A
L
T
L
L
E
K
Site 70
T757
V
N
P
N
T
A
L
T
L
L
E
K
M
K
D
Site 71
T788
D
K
Q
K
L
I
E
T
V
V
K
Q
L
R
S
Site 72
S795
T
V
V
K
Q
L
R
S
L
V
N
G
M
S
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation