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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SMARCC2
Full Name:
SWI/SNF complex subunit SMARCC2
Alias:
BAF170; CRACC2; Rsc8; SMRC2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin c2, isoform a; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2
Type:
DNA binding protein
Mass (Da):
132879
Number AA:
1214
UniProt ID:
Q8TAQ2
International Prot ID:
IPI00216047
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000785
GO:0005622
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0003677
GO:0003682
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006325
GO:0006333
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y14
D
G
G
P
N
V
K
Y
Y
E
A
A
D
T
V
Site 2
Y15
G
G
P
N
V
K
Y
Y
E
A
A
D
T
V
T
Site 3
T20
K
Y
Y
E
A
A
D
T
V
T
Q
F
D
N
V
Site 4
Y38
L
G
K
N
Y
K
K
Y
I
Q
A
E
P
P
T
Site 5
T45
Y
I
Q
A
E
P
P
T
N
K
S
L
S
S
L
Site 6
S48
A
E
P
P
T
N
K
S
L
S
S
L
V
V
Q
Site 7
S69
E
V
F
G
K
H
V
S
N
A
P
L
T
K
L
Site 8
S102
A
A
A
Y
K
F
K
S
D
Q
G
W
R
R
Y
Site 9
Y109
S
D
Q
G
W
R
R
Y
D
F
Q
N
P
S
R
Site 10
T126
R
N
V
E
M
F
M
T
I
E
K
S
L
V
Q
Site 11
Y179
N
N
A
S
H
V
V
Y
P
V
P
G
N
L
E
Site 12
Y207
Q
V
L
L
H
W
G
Y
Y
P
D
S
Y
D
T
Site 13
Y212
W
G
Y
Y
P
D
S
Y
D
T
W
I
P
A
S
Site 14
S219
Y
D
T
W
I
P
A
S
E
I
E
A
S
V
E
Site 15
S224
P
A
S
E
I
E
A
S
V
E
D
A
P
T
P
Site 16
T230
A
S
V
E
D
A
P
T
P
E
K
P
R
K
V
Site 17
Y257
E
W
M
N
E
E
D
Y
E
V
N
D
D
K
N
Site 18
S267
N
D
D
K
N
P
V
S
R
R
K
K
I
S
A
Site 19
S273
V
S
R
R
K
K
I
S
A
K
T
L
T
D
E
Site 20
T276
R
K
K
I
S
A
K
T
L
T
D
E
V
N
S
Site 21
T278
K
I
S
A
K
T
L
T
D
E
V
N
S
P
D
Site 22
S283
T
L
T
D
E
V
N
S
P
D
S
D
R
R
D
Site 23
S286
D
E
V
N
S
P
D
S
D
R
R
D
K
K
G
Site 24
S302
N
Y
K
K
R
K
R
S
P
S
P
S
P
T
P
Site 25
S304
K
K
R
K
R
S
P
S
P
S
P
T
P
E
A
Site 26
S306
R
K
R
S
P
S
P
S
P
T
P
E
A
K
K
Site 27
T308
R
S
P
S
P
S
P
T
P
E
A
K
K
K
N
Site 28
S321
K
N
A
K
K
G
P
S
T
P
Y
T
K
S
K
Site 29
T322
N
A
K
K
G
P
S
T
P
Y
T
K
S
K
R
Site 30
Y324
K
K
G
P
S
T
P
Y
T
K
S
K
R
G
H
Site 31
T325
K
G
P
S
T
P
Y
T
K
S
K
R
G
H
R
Site 32
S327
P
S
T
P
Y
T
K
S
K
R
G
H
R
E
E
Site 33
T340
E
E
E
Q
E
D
L
T
K
D
M
D
E
P
S
Site 34
S347
T
K
D
M
D
E
P
S
P
V
P
N
V
E
E
Site 35
T360
E
E
V
T
L
P
K
T
V
N
T
K
K
D
S
Site 36
S367
T
V
N
T
K
K
D
S
E
S
A
P
V
K
G
Site 37
S369
N
T
K
K
D
S
E
S
A
P
V
K
G
G
T
Site 38
T376
S
A
P
V
K
G
G
T
M
T
D
L
D
E
Q
Site 39
T378
P
V
K
G
G
T
M
T
D
L
D
E
Q
E
D
Site 40
S387
L
D
E
Q
E
D
E
S
M
E
T
T
G
K
D
Site 41
T390
Q
E
D
E
S
M
E
T
T
G
K
D
E
D
E
Site 42
S399
G
K
D
E
D
E
N
S
T
G
N
K
G
E
Q
Site 43
T400
K
D
E
D
E
N
S
T
G
N
K
G
E
Q
T
Site 44
T407
T
G
N
K
G
E
Q
T
K
N
P
D
L
H
E
Site 45
T418
D
L
H
E
D
N
V
T
E
Q
T
H
H
I
I
Site 46
Y435
S
Y
A
A
W
F
D
Y
N
S
V
H
A
I
E
Site 47
S456
F
F
N
G
K
N
K
S
K
T
P
E
I
Y
L
Site 48
T458
N
G
K
N
K
S
K
T
P
E
I
Y
L
A
Y
Site 49
Y462
K
S
K
T
P
E
I
Y
L
A
Y
R
N
F
M
Site 50
Y473
R
N
F
M
I
D
T
Y
R
L
N
P
Q
E
Y
Site 51
Y480
Y
R
L
N
P
Q
E
Y
L
T
S
T
A
C
R
Site 52
T484
P
Q
E
Y
L
T
S
T
A
C
R
R
N
L
A
Site 53
Y512
E
Q
W
G
L
I
N
Y
Q
V
D
A
E
S
R
Site 54
S518
N
Y
Q
V
D
A
E
S
R
P
T
P
M
G
P
Site 55
T521
V
D
A
E
S
R
P
T
P
M
G
P
P
P
T
Site 56
S529
P
M
G
P
P
P
T
S
H
F
H
V
L
A
D
Site 57
T548
L
V
P
L
Q
P
K
T
P
Q
Q
T
S
A
S
Site 58
S553
P
K
T
P
Q
Q
T
S
A
S
Q
Q
M
L
N
Site 59
S555
T
P
Q
Q
T
S
A
S
Q
Q
M
L
N
F
P
Site 60
T579
M
Q
N
F
G
L
R
T
D
M
Y
T
K
K
N
Site 61
Y582
F
G
L
R
T
D
M
Y
T
K
K
N
V
P
S
Site 62
T583
G
L
R
T
D
M
Y
T
K
K
N
V
P
S
K
Site 63
S591
K
K
N
V
P
S
K
S
K
A
A
A
S
A
T
Site 64
S596
S
K
S
K
A
A
A
S
A
T
R
E
W
T
E
Site 65
T602
A
S
A
T
R
E
W
T
E
Q
E
T
L
L
L
Site 66
Y648
R
L
P
I
E
D
P
Y
L
E
D
S
E
A
S
Site 67
S652
E
D
P
Y
L
E
D
S
E
A
S
L
G
P
L
Site 68
S655
Y
L
E
D
S
E
A
S
L
G
P
L
A
Y
Q
Site 69
S667
A
Y
Q
P
I
P
F
S
Q
S
G
N
P
V
M
Site 70
S669
Q
P
I
P
F
S
Q
S
G
N
P
V
M
S
T
Site 71
S695
V
A
S
A
A
A
K
S
A
L
E
E
F
S
K
Site 72
T709
K
M
K
E
E
V
P
T
A
L
V
E
A
H
V
Site 73
T726
V
E
E
A
A
K
V
T
G
K
A
D
P
A
F
Site 74
T743
E
S
S
G
I
A
G
T
T
S
D
E
P
E
R
Site 75
S745
S
G
I
A
G
T
T
S
D
E
P
E
R
I
E
Site 76
S754
E
P
E
R
I
E
E
S
G
N
D
E
A
R
V
Site 77
T766
A
R
V
E
G
Q
A
T
D
E
K
K
E
P
K
Site 78
T790
E
E
E
A
K
E
K
T
S
E
A
P
K
K
D
Site 79
S806
E
K
G
K
E
G
D
S
E
K
E
S
E
K
S
Site 80
S810
E
G
D
S
E
K
E
S
E
K
S
D
G
D
P
Site 81
S813
S
E
K
E
S
E
K
S
D
G
D
P
I
V
D
Site 82
S841
V
L
K
E
V
V
E
S
E
G
E
R
K
T
K
Site 83
T847
E
S
E
G
E
R
K
T
K
V
E
R
D
I
G
Site 84
T911
R
H
F
E
E
L
E
T
I
M
D
R
E
R
E
Site 85
Y922
R
E
R
E
A
L
E
Y
Q
R
Q
Q
L
L
A
Site 86
Y941
F
H
M
E
Q
L
K
Y
A
E
M
R
A
R
Q
Site 87
S969
P
P
A
L
P
P
G
S
Q
P
I
P
P
T
G
Site 88
T975
G
S
Q
P
I
P
P
T
G
A
A
G
P
P
A
Site 89
S1006
G
S
G
A
P
P
G
S
L
G
P
S
E
Q
I
Site 90
S1010
P
P
G
S
L
G
P
S
E
Q
I
G
Q
A
G
Site 91
S1049
P
P
G
P
H
G
P
S
P
F
P
N
Q
Q
T
Site 92
T1056
S
P
F
P
N
Q
Q
T
P
P
S
M
M
P
G
Site 93
S1059
P
N
Q
Q
T
P
P
S
M
M
P
G
A
V
P
Site 94
T1129
H
L
P
F
A
P
G
T
L
P
P
P
N
L
P
Site 95
S1138
P
P
P
N
L
P
V
S
M
A
N
P
L
H
P
Site 96
T1150
L
H
P
N
L
P
A
T
T
T
M
P
S
S
L
Site 97
T1151
H
P
N
L
P
A
T
T
T
M
P
S
S
L
P
Site 98
T1152
P
N
L
P
A
T
T
T
M
P
S
S
L
P
L
Site 99
S1155
P
A
T
T
T
M
P
S
S
L
P
L
G
P
G
Site 100
S1184
V
Q
G
N
L
L
P
S
A
S
P
L
P
D
P
Site 101
S1186
G
N
L
L
P
S
A
S
P
L
P
D
P
G
T
Site 102
T1193
S
P
L
P
D
P
G
T
P
L
P
P
D
P
T
Site 103
T1200
T
P
L
P
P
D
P
T
A
P
S
P
G
T
V
Site 104
S1203
P
P
D
P
T
A
P
S
P
G
T
V
T
P
V
Site 105
T1206
P
T
A
P
S
P
G
T
V
T
P
V
P
P
P
Site 106
T1208
A
P
S
P
G
T
V
T
P
V
P
P
P
Q
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation