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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RIN3
Full Name:
Ras and Rab interactor 3
Alias:
Ras interaction/interference protein 3
Type:
Mass (Da):
107854
Number AA:
985
UniProt ID:
Q8TB24
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
A
P
A
R
G
D
P
T
G
P
V
P
V
V
G
Site 2
S51
L
P
H
R
R
G
I
S
I
L
E
K
L
I
K
Site 3
S91
M
F
L
V
R
R
D
S
S
S
K
Q
L
V
L
Site 4
S92
F
L
V
R
R
D
S
S
S
K
Q
L
V
L
C
Site 5
S108
H
F
P
S
L
N
E
S
S
A
E
V
L
E
Y
Site 6
Y115
S
S
A
E
V
L
E
Y
T
I
K
E
E
K
S
Site 7
Y125
K
E
E
K
S
I
L
Y
L
E
G
S
A
L
V
Site 8
S182
L
G
L
G
F
W
D
S
S
L
N
P
P
Q
E
Site 9
S183
G
L
G
F
W
D
S
S
L
N
P
P
Q
E
R
Site 10
S209
P
G
F
P
L
V
S
S
L
R
P
T
A
H
D
Site 11
T213
L
V
S
S
L
R
P
T
A
H
D
A
N
C
A
Site 12
S244
P
I
F
I
E
D
C
S
S
A
L
P
T
D
Q
Site 13
S245
I
F
I
E
D
C
S
S
A
L
P
T
D
Q
P
Site 14
T249
D
C
S
S
A
L
P
T
D
Q
P
P
L
G
N
Site 15
T265
P
A
R
P
L
P
P
T
S
D
A
T
S
P
T
Site 16
S266
A
R
P
L
P
P
T
S
D
A
T
S
P
T
S
Site 17
T269
L
P
P
T
S
D
A
T
S
P
T
S
R
W
A
Site 18
S270
P
P
T
S
D
A
T
S
P
T
S
R
W
A
P
Site 19
T272
T
S
D
A
T
S
P
T
S
R
W
A
P
R
R
Site 20
S273
S
D
A
T
S
P
T
S
R
W
A
P
R
R
P
Site 21
S314
P
A
C
P
L
P
T
S
P
P
V
P
A
P
H
Site 22
T323
P
V
P
A
P
H
V
T
P
H
A
P
G
P
P
Site 23
T340
P
N
Q
P
P
M
M
T
C
E
R
L
P
C
P
Site 24
T348
C
E
R
L
P
C
P
T
A
G
L
G
P
L
R
Site 25
S366
M
K
P
G
A
A
S
S
P
L
Q
Q
V
P
A
Site 26
T384
P
A
K
K
N
L
P
T
A
P
P
R
R
R
V
Site 27
S392
A
P
P
R
R
R
V
S
E
R
V
S
L
E
D
Site 28
S396
R
R
V
S
E
R
V
S
L
E
D
Q
S
P
G
Site 29
S401
R
V
S
L
E
D
Q
S
P
G
M
A
A
E
G
Site 30
S412
A
A
E
G
D
Q
L
S
L
P
P
Q
G
T
S
Site 31
S419
S
L
P
P
Q
G
T
S
D
G
P
E
D
T
P
Site 32
T425
T
S
D
G
P
E
D
T
P
R
E
S
T
E
Q
Site 33
S429
P
E
D
T
P
R
E
S
T
E
Q
G
Q
D
T
Site 34
T430
E
D
T
P
R
E
S
T
E
Q
G
Q
D
T
E
Site 35
T436
S
T
E
Q
G
Q
D
T
E
V
K
A
S
D
P
Site 36
S441
Q
D
T
E
V
K
A
S
D
P
H
S
M
P
E
Site 37
S445
V
K
A
S
D
P
H
S
M
P
E
L
P
R
T
Site 38
T452
S
M
P
E
L
P
R
T
A
K
Q
P
P
V
P
Site 39
S467
P
P
R
K
K
R
I
S
R
Q
L
A
S
T
L
Site 40
S472
R
I
S
R
Q
L
A
S
T
L
P
A
P
L
E
Site 41
T473
I
S
R
Q
L
A
S
T
L
P
A
P
L
E
N
Site 42
T492
T
Q
A
M
A
L
E
T
P
T
P
G
P
P
R
Site 43
T494
A
M
A
L
E
T
P
T
P
G
P
P
R
E
G
Site 44
S503
G
P
P
R
E
G
Q
S
P
A
S
Q
A
G
T
Site 45
S506
R
E
G
Q
S
P
A
S
Q
A
G
T
Q
H
P
Site 46
T510
S
P
A
S
Q
A
G
T
Q
H
P
P
A
Q
A
Site 47
S521
P
A
Q
A
T
A
H
S
Q
S
S
P
E
F
K
Site 48
S524
A
T
A
H
S
Q
S
S
P
E
F
K
G
S
L
Site 49
S530
S
S
P
E
F
K
G
S
L
A
S
L
S
D
S
Site 50
S541
L
S
D
S
L
G
V
S
V
M
A
T
D
Q
D
Site 51
T545
L
G
V
S
V
M
A
T
D
Q
D
S
Y
S
T
Site 52
S549
V
M
A
T
D
Q
D
S
Y
S
T
S
S
T
E
Site 53
Y550
M
A
T
D
Q
D
S
Y
S
T
S
S
T
E
E
Site 54
S551
A
T
D
Q
D
S
Y
S
T
S
S
T
E
E
E
Site 55
S553
D
Q
D
S
Y
S
T
S
S
T
E
E
E
L
E
Site 56
S554
Q
D
S
Y
S
T
S
S
T
E
E
E
L
E
Q
Site 57
T555
D
S
Y
S
T
S
S
T
E
E
E
L
E
Q
F
Site 58
S564
E
E
L
E
Q
F
S
S
P
S
V
K
K
K
P
Site 59
S566
L
E
Q
F
S
S
P
S
V
K
K
K
P
S
M
Site 60
S583
G
K
A
R
H
R
L
S
F
A
S
F
S
S
M
Site 61
S586
R
H
R
L
S
F
A
S
F
S
S
M
F
H
A
Site 62
Y602
L
S
N
N
R
K
L
Y
K
K
V
V
E
L
A
Site 63
S614
E
L
A
Q
D
K
G
S
Y
F
G
S
L
V
Q
Site 64
S618
D
K
G
S
Y
F
G
S
L
V
Q
D
Y
K
V
Site 65
Y623
F
G
S
L
V
Q
D
Y
K
V
Y
S
L
E
M
Site 66
T635
L
E
M
M
A
R
Q
T
S
S
T
E
M
L
Q
Site 67
S636
E
M
M
A
R
Q
T
S
S
T
E
M
L
Q
E
Site 68
T638
M
A
R
Q
T
S
S
T
E
M
L
Q
E
I
R
Site 69
T649
Q
E
I
R
T
M
M
T
Q
L
K
S
Y
L
L
Site 70
S653
T
M
M
T
Q
L
K
S
Y
L
L
Q
S
T
E
Site 71
Y654
M
M
T
Q
L
K
S
Y
L
L
Q
S
T
E
L
Site 72
S671
L
V
D
P
A
L
H
S
E
E
E
L
E
A
I
Site 73
S697
P
L
K
E
A
I
N
S
C
L
H
Q
I
H
S
Site 74
S704
S
C
L
H
Q
I
H
S
K
D
G
S
L
Q
Q
Site 75
S708
Q
I
H
S
K
D
G
S
L
Q
Q
L
K
E
N
Site 76
S748
K
I
L
Q
K
F
T
S
M
H
K
A
Y
S
P
Site 77
S754
T
S
M
H
K
A
Y
S
P
E
K
K
I
S
I
Site 78
S760
Y
S
P
E
K
K
I
S
I
L
L
K
T
C
K
Site 79
Y782
L
G
N
P
G
K
P
Y
G
A
D
D
F
L
P
Site 80
Y793
D
F
L
P
V
L
M
Y
V
L
A
R
S
N
L
Site 81
Y825
L
Q
L
G
E
G
S
Y
Y
L
T
T
T
Y
G
Site 82
Y826
Q
L
G
E
G
S
Y
Y
L
T
T
T
Y
G
A
Site 83
T828
G
E
G
S
Y
Y
L
T
T
T
Y
G
A
L
E
Site 84
T829
E
G
S
Y
Y
L
T
T
T
Y
G
A
L
E
H
Site 85
Y831
S
Y
Y
L
T
T
T
Y
G
A
L
E
H
I
K
Site 86
S839
G
A
L
E
H
I
K
S
Y
D
K
I
T
V
T
Site 87
T844
I
K
S
Y
D
K
I
T
V
T
R
Q
L
S
V
Site 88
T846
S
Y
D
K
I
T
V
T
R
Q
L
S
V
E
V
Site 89
S856
L
S
V
E
V
Q
D
S
I
H
R
W
E
R
R
Site 90
T865
H
R
W
E
R
R
R
T
L
N
K
A
R
A
S
Site 91
S872
T
L
N
K
A
R
A
S
R
S
S
V
Q
D
F
Site 92
S874
N
K
A
R
A
S
R
S
S
V
Q
D
F
I
C
Site 93
S875
K
A
R
A
S
R
S
S
V
Q
D
F
I
C
V
Site 94
Y884
Q
D
F
I
C
V
S
Y
L
E
P
E
Q
Q
A
Site 95
T893
E
P
E
Q
Q
A
R
T
L
A
S
R
A
D
T
Site 96
S896
Q
Q
A
R
T
L
A
S
R
A
D
T
Q
A
Q
Site 97
Y946
L
P
H
C
I
K
G
Y
L
L
R
S
E
P
K
Site 98
S950
I
K
G
Y
L
L
R
S
E
P
K
R
D
F
H
Site 99
Y960
K
R
D
F
H
F
V
Y
R
P
L
D
G
G
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation