KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ABHD4
Full Name:
Abhydrolase domain-containing protein 4
Alias:
Alpha/beta-hydrolase 4;Lyso-N-acylphosphatidylethanolamine lipase
Type:
Mass (Da):
38794
Number AA:
342
UniProt ID:
Q8TB40
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
A
D
D
L
E
Q
Q
S
Q
G
W
L
S
S
W
Site 2
S15
Q
S
Q
G
W
L
S
S
W
L
P
T
W
R
P
Site 3
T19
W
L
S
S
W
L
P
T
W
R
P
T
S
M
S
Site 4
T23
W
L
P
T
W
R
P
T
S
M
S
Q
L
K
N
Site 5
S24
L
P
T
W
R
P
T
S
M
S
Q
L
K
N
V
Site 6
S26
T
W
R
P
T
S
M
S
Q
L
K
N
V
E
A
Site 7
Y47
Q
N
K
F
L
A
R
Y
V
S
L
P
N
Q
N
Site 8
S49
K
F
L
A
R
Y
V
S
L
P
N
Q
N
K
I
Site 9
T58
P
N
Q
N
K
I
W
T
V
T
V
S
P
E
Q
Site 10
T60
Q
N
K
I
W
T
V
T
V
S
P
E
Q
N
D
Site 11
S62
K
I
W
T
V
T
V
S
P
E
Q
N
D
R
T
Site 12
T69
S
P
E
Q
N
D
R
T
P
L
V
M
V
H
G
Site 13
S92
I
L
N
M
D
S
L
S
A
R
R
T
L
H
T
Site 14
T96
D
S
L
S
A
R
R
T
L
H
T
F
D
L
L
Site 15
T99
S
A
R
R
T
L
H
T
F
D
L
L
G
F
G
Site 16
S108
D
L
L
G
F
G
R
S
S
R
P
A
F
P
R
Site 17
S109
L
L
G
F
G
R
S
S
R
P
A
F
P
R
D
Site 18
S127
A
E
D
E
F
V
T
S
I
E
T
W
R
E
T
Site 19
T134
S
I
E
T
W
R
E
T
M
G
I
P
S
M
I
Site 20
S154
L
G
G
F
L
A
T
S
Y
S
I
K
Y
P
D
Site 21
Y155
G
G
F
L
A
T
S
Y
S
I
K
Y
P
D
R
Site 22
S156
G
F
L
A
T
S
Y
S
I
K
Y
P
D
R
V
Site 23
Y159
A
T
S
Y
S
I
K
Y
P
D
R
V
K
H
L
Site 24
T179
W
G
F
P
L
R
P
T
N
P
S
E
I
R
A
Site 25
S182
P
L
R
P
T
N
P
S
E
I
R
A
P
P
A
Site 26
Y241
E
D
D
T
I
S
E
Y
I
Y
H
C
N
A
Q
Site 27
Y243
D
T
I
S
E
Y
I
Y
H
C
N
A
Q
N
P
Site 28
T284
I
R
K
D
V
P
I
T
M
I
Y
G
S
D
T
Site 29
T291
T
M
I
Y
G
S
D
T
W
I
D
T
S
T
G
Site 30
T295
G
S
D
T
W
I
D
T
S
T
G
K
K
V
K
Site 31
S296
S
D
T
W
I
D
T
S
T
G
K
K
V
K
M
Site 32
S308
V
K
M
Q
R
P
D
S
Y
V
R
D
M
E
I
Site 33
Y309
K
M
Q
R
P
D
S
Y
V
R
D
M
E
I
K
Site 34
Y323
K
G
A
S
H
H
V
Y
A
D
Q
P
H
I
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation