PhosphoNET

           
Protein Info 
   
Short Name:  PUM2
Full Name:  Pumilio homolog 2
Alias:  KIAA0235; PUMH2; Pumilio 2; Pumilio2
Type:  RNA binding protein
Mass (Da):  114216
Number AA:  1066
UniProt ID:  Q8TB72
International Prot ID:  IPI00398749
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737     Uniprot OncoNet
Molecular Function:  GO:0003723  GO:0005515   PhosphoSite+ KinaseNET
Biological Process:  GO:0006417     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T21GMGELLPTKKFWEPD
Site 2S30KFWEPDDSTKDGQKG
Site 3T31FWEPDDSTKDGQKGI
Site 4S53RETAWGASHHSMSQP
Site 5S58GASHHSMSQPIMVQR
Site 6S67PIMVQRRSGQGFHGN
Site 7S75GQGFHGNSEVNAILS
Site 8S82SEVNAILSPRSESGG
Site 9S85NAILSPRSESGGLGV
Site 10Y97LGVSMVEYVLSSSPA
Site 11S100SMVEYVLSSSPADKL
Site 12S101MVEYVLSSSPADKLD
Site 13S102VEYVLSSSPADKLDS
Site 14S109SPADKLDSRFRKGNF
Site 15T123FGTRDAETDGPEKGD
Site 16S136GDQKGKASPFEEDQN
Site 17S154KQGDDDDSKINGRGL
Site 18T175DCKDFNRTPGSRQAS
Site 19S178DFNRTPGSRQASPTE
Site 20S182TPGSRQASPTEVVER
Site 21T184GSRQASPTEVVERLG
Site 22T194VERLGPNTNPSEGLG
Site 23S197LGPNTNPSEGLGPLP
Site 24S217KPLVEEFSNPETQNL
Site 25T221EEFSNPETQNLDAME
Site 26Y239LESLQFDYPGNQVPM
Site 27S248GNQVPMDSSGATVGL
Site 28T252PMDSSGATVGLFDYN
Site 29Y258ATVGLFDYNSQQQLF
Site 30S260VGLFDYNSQQQLFQR
Site 31T272FQRTNALTVQQLTAA
Site 32S315VPNPYIISAAPPGTD
Site 33Y353YGVPWGVYPANLFQQ
Site 34S371AAANNTASQQAASQA
Site 35T396GAGQRPLTPNQGQQG
Site 36S489AAAGGTASSLTGSTN
Site 37S490AAGGTASSLTGSTNG
Site 38T492GGTASSLTGSTNGLF
Site 39S494TASSLTGSTNGLFRP
Site 40T504GLFRPIGTQPPQQQQ
Site 41S515QQQQQQPSTNLQSNS
Site 42T516QQQQQPSTNLQSNSF
Site 43S520QPSTNLQSNSFYGSS
Site 44S522STNLQSNSFYGSSSL
Site 45Y524NLQSNSFYGSSSLTN
Site 46S526QSNSFYGSSSLTNSS
Site 47S528NSFYGSSSLTNSSQS
Site 48T530FYGSSSLTNSSQSSS
Site 49S532GSSSLTNSSQSSSLF
Site 50S533SSSLTNSSQSSSLFS
Site 51S535SLTNSSQSSSLFSHG
Site 52S536LTNSSQSSSLFSHGP
Site 53S537TNSSQSSSLFSHGPG
Site 54S540SQSSSLFSHGPGQPG
Site 55S548HGPGQPGSTSLGFGS
Site 56S550PGQPGSTSLGFGSGN
Site 57S576GFGSSVGSSASSSAT
Site 58S577FGSSVGSSASSSATR
Site 59S579SSVGSSASSSATRRE
Site 60S580SVGSSASSSATRRES
Site 61S581VGSSASSSATRRESL
Site 62T583SSASSSATRRESLST
Site 63S587SSATRRESLSTSSDL
Site 64S589ATRRESLSTSSDLYK
Site 65T590TRRESLSTSSDLYKR
Site 66S591RRESLSTSSDLYKRS
Site 67S592RESLSTSSDLYKRSS
Site 68Y595LSTSSDLYKRSSSSL
Site 69S598SSDLYKRSSSSLAPI
Site 70S599SDLYKRSSSSLAPIG
Site 71S600DLYKRSSSSLAPIGQ
Site 72S601LYKRSSSSLAPIGQP
Site 73Y610APIGQPFYNSLGFSS
Site 74S612IGQPFYNSLGFSSSP
Site 75S616FYNSLGFSSSPSPIG
Site 76S617YNSLGFSSSPSPIGM
Site 77S618NSLGFSSSPSPIGMP
Site 78S628PIGMPLPSQTPGHSL
Site 79T630GMPLPSQTPGHSLTP
Site 80S634PSQTPGHSLTPPPSL
Site 81T636QTPGHSLTPPPSLSS
Site 82S640HSLTPPPSLSSHGSS
Site 83S642LTPPPSLSSHGSSSS
Site 84S643TPPPSLSSHGSSSSL
Site 85S646PSLSSHGSSSSLHLG
Site 86S647SLSSHGSSSSLHLGG
Site 87S648LSSHGSSSSLHLGGL
Site 88S649SSHGSSSSLHLGGLT
Site 89S664NGSGRYISAAPGAEA
Site 90Y673APGAEAKYRSASSTS
Site 91S675GAEAKYRSASSTSSL
Site 92S677EAKYRSASSTSSLFS
Site 93S678AKYRSASSTSSLFSS
Site 94T679KYRSASSTSSLFSSS
Site 95S680YRSASSTSSLFSSSS
Site 96S681RSASSTSSLFSSSSQ
Site 97S684SSTSSLFSSSSQLFP
Site 98S685STSSLFSSSSQLFPP
Site 99S686TSSLFSSSSQLFPPS
Site 100S687SSLFSSSSQLFPPSR
Site 101S693SSQLFPPSRLRYNRS
Site 102Y697FPPSRLRYNRSDIMP
Site 103S700SRLRYNRSDIMPSGR
Site 104S705NRSDIMPSGRSRLLE
Site 105S735IGHIVEFSQDQHGSR
Site 106T752QQKLERATPAERQMV
Site 107S788QKFFEFGSLDQKLAL
Site 108S822VIQKALESISSDQQV
Site 109S825KALESISSDQQVISE
Site 110Y921EQLVQDQYGNYVIQH
Site 111Y924VQDQYGNYVIQHVLE
Site 112S939HGRPEDKSKIVSEIR
Site 113S943EDKSKIVSEIRGKVL
Site 114S953RGKVLALSQHKFASN
Site 115T967NVVEKCVTHASRAER
Site 116Y993DGPHSALYTMMKDQY
Site 117T994GPHSALYTMMKDQYA
Site 118Y1000YTMMKDQYANYVVQK
Site 119Y1003MKDQYANYVVQKMID
Site 120T1030KIRPHITTLRKYTYG
Site 121Y1034HITTLRKYTYGKHIL
Site 122T1035ITTLRKYTYGKHILA
Site 123Y1036TTLRKYTYGKHILAK
Site 124Y1047ILAKLEKYYLKNSPD
Site 125Y1048LAKLEKYYLKNSPDL
Site 126S1052EKYYLKNSPDLGPIG
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation