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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ITFG1
Full Name:
T-cell immunomodulatory protein
Alias:
Integrin-alpha FG-GAP repeat-containing protein 1
Type:
Mass (Da):
68108
Number AA:
612
UniProt ID:
Q8TB96
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S58
A
A
F
G
D
L
N
S
D
K
Q
T
D
L
F
Site 2
T62
D
L
N
S
D
K
Q
T
D
L
F
V
L
R
E
Site 3
Y84
L
A
D
Q
N
A
P
Y
F
K
P
K
V
K
V
Site 4
S92
F
K
P
K
V
K
V
S
F
K
N
H
S
A
L
Site 5
T101
K
N
H
S
A
L
I
T
S
V
V
P
G
D
Y
Site 6
S102
N
H
S
A
L
I
T
S
V
V
P
G
D
Y
D
Site 7
Y108
T
S
V
V
P
G
D
Y
D
G
D
S
Q
M
D
Site 8
S112
P
G
D
Y
D
G
D
S
Q
M
D
V
L
L
T
Site 9
T119
S
Q
M
D
V
L
L
T
Y
L
P
K
N
Y
A
Site 10
Y120
Q
M
D
V
L
L
T
Y
L
P
K
N
Y
A
K
Site 11
T153
N
M
T
I
L
N
R
T
F
Q
D
E
P
L
I
Site 12
T196
L
S
W
H
P
A
L
T
T
T
S
K
M
R
I
Site 13
S199
H
P
A
L
T
T
T
S
K
M
R
I
P
H
S
Site 14
S206
S
K
M
R
I
P
H
S
H
A
F
I
D
L
T
Site 15
T231
T
L
N
A
T
T
S
T
F
Q
F
E
I
W
E
Site 16
S245
E
N
L
D
G
N
F
S
V
S
T
I
L
E
K
Site 17
S288
E
D
K
N
C
Q
K
S
T
I
Y
L
V
R
S
Site 18
Y291
N
C
Q
K
S
T
I
Y
L
V
R
S
G
M
K
Site 19
S308
V
P
V
L
Q
D
F
S
N
K
G
T
L
W
G
Site 20
T312
Q
D
F
S
N
K
G
T
L
W
G
F
V
P
F
Site 21
T326
F
V
D
E
Q
Q
P
T
E
I
P
I
P
I
T
Site 22
Y339
I
T
L
H
I
G
D
Y
N
M
D
G
Y
P
D
Site 23
Y384
A
R
R
M
F
K
V
Y
W
E
L
T
D
L
N
Site 24
T420
V
V
L
S
K
G
Y
T
K
N
D
F
A
I
H
Site 25
T458
N
D
C
P
R
K
I
T
P
F
G
V
N
Q
P
Site 26
Y471
Q
P
G
P
Y
I
M
Y
T
T
V
D
A
N
G
Site 27
Y479
T
T
V
D
A
N
G
Y
L
K
N
G
S
A
G
Site 28
S484
N
G
Y
L
K
N
G
S
A
G
Q
L
S
Q
S
Site 29
S489
N
G
S
A
G
Q
L
S
Q
S
A
H
L
A
L
Site 30
Y516
A
N
F
L
D
H
L
Y
V
G
I
P
R
P
S
Site 31
S523
Y
V
G
I
P
R
P
S
G
E
K
S
I
R
K
Site 32
S527
P
R
P
S
G
E
K
S
I
R
K
Q
E
W
T
Site 33
T534
S
I
R
K
Q
E
W
T
A
I
I
P
N
S
Q
Site 34
Y547
S
Q
L
I
V
I
P
Y
P
H
N
V
P
R
S
Site 35
S554
Y
P
H
N
V
P
R
S
W
S
A
K
L
Y
L
Site 36
S556
H
N
V
P
R
S
W
S
A
K
L
Y
L
T
P
Site 37
Y560
R
S
W
S
A
K
L
Y
L
T
P
S
N
I
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation