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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SHKBP1
Full Name:
SH3KBP1-binding protein 1
Alias:
Type:
Uncharacterized
Mass (Da):
76344
Number AA:
707
UniProt ID:
Q8TBC3
International Prot ID:
IPI00163403
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0008076
Uniprot
OncoNet
Molecular Function:
GO:0005249
PhosphoSite+
KinaseNET
Biological Process:
GO:0006813
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
T
A
A
E
G
V
P
S
R
G
P
P
G
E
V
Site 2
S31
N
V
G
G
K
R
F
S
T
S
R
Q
T
L
T
Site 3
T32
V
G
G
K
R
F
S
T
S
R
Q
T
L
T
W
Site 4
S33
G
G
K
R
F
S
T
S
R
Q
T
L
T
W
I
Site 5
T36
R
F
S
T
S
R
Q
T
L
T
W
I
P
D
S
Site 6
T38
S
T
S
R
Q
T
L
T
W
I
P
D
S
F
F
Site 7
S54
S
L
L
S
G
R
I
S
T
L
K
D
E
T
G
Site 8
T55
L
L
S
G
R
I
S
T
L
K
D
E
T
G
A
Site 9
T81
P
I
L
N
F
L
R
T
K
E
L
D
P
R
G
Site 10
S92
D
P
R
G
V
H
G
S
S
L
L
H
E
A
Q
Site 11
S93
P
R
G
V
H
G
S
S
L
L
H
E
A
Q
F
Site 12
T104
E
A
Q
F
Y
G
L
T
P
L
V
R
R
L
Q
Site 13
S119
L
R
E
E
L
D
R
S
S
C
G
N
V
L
F
Site 14
S120
R
E
E
L
D
R
S
S
C
G
N
V
L
F
N
Site 15
S144
V
K
R
R
N
R
H
S
L
V
G
P
Q
Q
L
Site 16
S161
R
P
A
P
V
R
R
S
N
T
M
P
P
N
L
Site 17
T163
A
P
V
R
R
S
N
T
M
P
P
N
L
G
N
Site 18
T182
G
R
M
L
D
E
K
T
P
P
S
P
S
G
Q
Site 19
S185
L
D
E
K
T
P
P
S
P
S
G
Q
P
E
E
Site 20
S187
E
K
T
P
P
S
P
S
G
Q
P
E
E
P
G
Site 21
S230
S
G
W
Q
L
V
F
S
S
P
R
L
D
W
P
Site 22
S231
G
W
Q
L
V
F
S
S
P
R
L
D
W
P
I
Site 23
S304
G
N
Q
L
I
A
T
S
H
T
G
R
I
G
V
Site 24
Y347
G
C
N
N
G
S
I
Y
Y
V
D
V
Q
K
F
Site 25
Y348
C
N
N
G
S
I
Y
Y
V
D
V
Q
K
F
P
Site 26
Y369
D
L
L
V
S
E
L
Y
R
D
P
A
E
D
G
Site 27
S381
E
D
G
V
T
A
L
S
V
Y
L
T
P
K
T
Site 28
T385
T
A
L
S
V
Y
L
T
P
K
T
S
D
S
G
Site 29
T388
S
V
Y
L
T
P
K
T
S
D
S
G
N
W
I
Site 30
S389
V
Y
L
T
P
K
T
S
D
S
G
N
W
I
E
Site 31
Y399
G
N
W
I
E
I
A
Y
G
T
S
S
G
G
V
Site 32
S418
Q
H
P
E
T
V
G
S
G
P
Q
L
F
Q
T
Site 33
T425
S
G
P
Q
L
F
Q
T
F
T
V
H
R
S
P
Site 34
T427
P
Q
L
F
Q
T
F
T
V
H
R
S
P
V
T
Site 35
S445
L
S
E
K
H
L
I
S
V
C
A
D
N
N
H
Site 36
S466
T
R
F
R
G
M
I
S
T
Q
P
G
S
T
P
Site 37
T467
R
F
R
G
M
I
S
T
Q
P
G
S
T
P
L
Site 38
S471
M
I
S
T
Q
P
G
S
T
P
L
A
S
F
K
Site 39
T472
I
S
T
Q
P
G
S
T
P
L
A
S
F
K
I
Site 40
S476
P
G
S
T
P
L
A
S
F
K
I
L
A
L
E
Site 41
Y500
A
G
N
D
I
G
P
Y
G
E
R
D
D
Q
Q
Site 42
S525
S
Q
L
F
V
R
L
S
S
T
G
Q
R
V
C
Site 43
S526
Q
L
F
V
R
L
S
S
T
G
Q
R
V
C
S
Site 44
S533
S
T
G
Q
R
V
C
S
V
R
S
V
D
G
S
Site 45
S536
Q
R
V
C
S
V
R
S
V
D
G
S
P
T
T
Site 46
S540
S
V
R
S
V
D
G
S
P
T
T
A
F
T
V
Site 47
T546
G
S
P
T
T
A
F
T
V
L
E
C
E
G
S
Site 48
S553
T
V
L
E
C
E
G
S
R
R
L
G
S
R
P
Site 49
S558
E
G
S
R
R
L
G
S
R
P
R
R
Y
L
L
Site 50
Y563
L
G
S
R
P
R
R
Y
L
L
T
G
Q
A
N
Site 51
T566
R
P
R
R
Y
L
L
T
G
Q
A
N
G
S
L
Site 52
S616
P
P
A
P
S
A
P
S
W
G
C
L
P
S
P
Site 53
S622
P
S
W
G
C
L
P
S
P
S
P
R
I
S
L
Site 54
S624
W
G
C
L
P
S
P
S
P
R
I
S
L
T
S
Site 55
S628
P
S
P
S
P
R
I
S
L
T
S
L
H
S
A
Site 56
T630
P
S
P
R
I
S
L
T
S
L
H
S
A
S
S
Site 57
S631
S
P
R
I
S
L
T
S
L
H
S
A
S
S
N
Site 58
S634
I
S
L
T
S
L
H
S
A
S
S
N
T
S
L
Site 59
S636
L
T
S
L
H
S
A
S
S
N
T
S
L
S
G
Site 60
S637
T
S
L
H
S
A
S
S
N
T
S
L
S
G
H
Site 61
S640
H
S
A
S
S
N
T
S
L
S
G
H
R
G
S
Site 62
S642
A
S
S
N
T
S
L
S
G
H
R
G
S
P
S
Site 63
S647
S
L
S
G
H
R
G
S
P
S
P
P
Q
A
E
Site 64
S649
S
G
H
R
G
S
P
S
P
P
Q
A
E
A
R
Site 65
S662
A
R
R
R
G
G
G
S
F
V
E
R
C
Q
E
Site 66
S673
R
C
Q
E
L
V
R
S
G
P
D
L
R
R
P
Site 67
T682
P
D
L
R
R
P
P
T
P
A
P
W
P
S
S
Site 68
S688
P
T
P
A
P
W
P
S
S
G
L
G
T
P
L
Site 69
S689
T
P
A
P
W
P
S
S
G
L
G
T
P
L
T
Site 70
T693
W
P
S
S
G
L
G
T
P
L
T
P
P
K
M
Site 71
T696
S
G
L
G
T
P
L
T
P
P
K
M
K
L
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation