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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UBA3
Full Name:
NEDD8-activating enzyme E1 catalytic subunit
Alias:
Ubiquitin-like modifier-activating enzyme 3
Type:
Mass (Da):
51834
Number AA:
463
UniProt ID:
Q8TBC4
International Prot ID:
IPI00328154
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003824
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0000278
GO:0006464
GO:0006508
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T31
V
D
G
G
C
G
D
T
G
D
W
E
G
R
W
Site 2
T52
L
E
R
S
G
P
F
T
H
P
D
F
E
P
S
Site 3
S59
T
H
P
D
F
E
P
S
T
E
S
L
Q
F
L
Site 4
T60
H
P
D
F
E
P
S
T
E
S
L
Q
F
L
L
Site 5
S62
D
F
E
P
S
T
E
S
L
Q
F
L
L
D
T
Site 6
S91
L
L
K
N
L
A
L
S
G
F
R
Q
I
H
V
Site 7
T103
I
H
V
I
D
M
D
T
I
D
V
S
N
L
N
Site 8
S107
D
M
D
T
I
D
V
S
N
L
N
R
Q
F
L
Site 9
Y156
Q
D
F
N
D
T
F
Y
R
Q
F
H
I
I
V
Site 10
T203
V
P
L
I
D
G
G
T
E
G
F
K
G
N
A
Site 11
Y252
L
P
E
H
C
I
E
Y
V
R
M
L
Q
W
P
Site 12
S290
Q
K
S
L
E
R
A
S
Q
Y
N
I
R
G
V
Site 13
Y292
S
L
E
R
A
S
Q
Y
N
I
R
G
V
T
Y
Site 14
T298
Q
Y
N
I
R
G
V
T
Y
R
L
T
Q
G
V
Site 15
T302
R
G
V
T
Y
R
L
T
Q
G
V
V
K
R
I
Site 16
Y352
F
N
D
V
D
G
L
Y
T
Y
T
F
E
A
E
Site 17
T353
N
D
V
D
G
L
Y
T
Y
T
F
E
A
E
R
Site 18
T355
V
D
G
L
Y
T
Y
T
F
E
A
E
R
K
E
Site 19
S377
L
P
Q
N
I
Q
F
S
P
S
A
K
L
Q
E
Site 20
Y388
K
L
Q
E
V
L
D
Y
L
T
N
S
A
S
L
Site 21
T390
Q
E
V
L
D
Y
L
T
N
S
A
S
L
Q
M
Site 22
S392
V
L
D
Y
L
T
N
S
A
S
L
Q
M
K
S
Site 23
S394
D
Y
L
T
N
S
A
S
L
Q
M
K
S
P
A
Site 24
S399
S
A
S
L
Q
M
K
S
P
A
I
T
A
T
L
Site 25
T403
Q
M
K
S
P
A
I
T
A
T
L
E
G
K
N
Site 26
T405
K
S
P
A
I
T
A
T
L
E
G
K
N
R
T
Site 27
Y414
E
G
K
N
R
T
L
Y
L
Q
S
V
T
S
I
Site 28
S420
L
Y
L
Q
S
V
T
S
I
E
E
R
T
R
P
Site 29
S430
E
R
T
R
P
N
L
S
K
T
L
K
E
L
G
Site 30
T432
T
R
P
N
L
S
K
T
L
K
E
L
G
L
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation