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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PMFBP1
Full Name:
Polyamine-modulated factor 1-binding protein 1
Alias:
Type:
Mass (Da):
119033
Number AA:
1022
UniProt ID:
Q8TBY8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
G
E
R
D
R
E
V
S
S
L
N
S
K
L
L
Site 2
S14
E
R
D
R
E
V
S
S
L
N
S
K
L
L
S
Site 3
S17
R
E
V
S
S
L
N
S
K
L
L
S
L
Q
L
Site 4
S21
S
L
N
S
K
L
L
S
L
Q
L
D
I
K
N
Site 5
T39
V
C
K
R
Q
R
K
T
L
Q
D
N
Q
L
C
Site 6
S68
Q
A
L
A
F
E
E
S
E
V
E
F
G
S
S
Site 7
S75
S
E
V
E
F
G
S
S
K
Q
C
H
L
R
Q
Site 8
T106
F
H
T
E
E
L
Q
T
S
Y
Y
S
L
R
Q
Site 9
S107
H
T
E
E
L
Q
T
S
Y
Y
S
L
R
Q
Y
Site 10
Y108
T
E
E
L
Q
T
S
Y
Y
S
L
R
Q
Y
Q
Site 11
Y109
E
E
L
Q
T
S
Y
Y
S
L
R
Q
Y
Q
S
Site 12
S110
E
L
Q
T
S
Y
Y
S
L
R
Q
Y
Q
S
I
Site 13
Y114
S
Y
Y
S
L
R
Q
Y
Q
S
I
L
E
K
Q
Site 14
S116
Y
S
L
R
Q
Y
Q
S
I
L
E
K
Q
T
S
Site 15
S123
S
I
L
E
K
Q
T
S
D
L
V
L
L
H
H
Site 16
Y142
K
E
D
E
V
I
L
Y
E
E
E
M
G
N
H
Site 17
S177
K
I
A
S
L
E
R
S
L
N
L
Y
R
D
K
Site 18
Y181
L
E
R
S
L
N
L
Y
R
D
K
Y
Q
S
S
Site 19
Y185
L
N
L
Y
R
D
K
Y
Q
S
S
L
S
N
I
Site 20
S187
L
Y
R
D
K
Y
Q
S
S
L
S
N
I
E
L
Site 21
S188
Y
R
D
K
Y
Q
S
S
L
S
N
I
E
L
L
Site 22
S190
D
K
Y
Q
S
S
L
S
N
I
E
L
L
E
C
Site 23
S221
P
E
N
K
G
D
H
S
K
V
R
I
Y
T
S
Site 24
Y226
D
H
S
K
V
R
I
Y
T
S
P
C
M
I
Q
Site 25
T227
H
S
K
V
R
I
Y
T
S
P
C
M
I
Q
E
Site 26
S228
S
K
V
R
I
Y
T
S
P
C
M
I
Q
E
H
Site 27
T238
M
I
Q
E
H
Q
E
T
Q
K
R
L
S
E
V
Site 28
S243
Q
E
T
Q
K
R
L
S
E
V
W
Q
K
V
S
Site 29
S250
S
E
V
W
Q
K
V
S
Q
Q
D
D
L
I
Q
Site 30
S286
K
L
Q
A
D
F
A
S
C
T
A
T
H
R
Y
Site 31
T290
D
F
A
S
C
T
A
T
H
R
Y
P
P
S
S
Site 32
Y293
S
C
T
A
T
H
R
Y
P
P
S
S
S
E
E
Site 33
S296
A
T
H
R
Y
P
P
S
S
S
E
E
C
E
D
Site 34
S297
T
H
R
Y
P
P
S
S
S
E
E
C
E
D
I
Site 35
S298
H
R
Y
P
P
S
S
S
E
E
C
E
D
I
K
Site 36
S317
H
L
Q
E
Q
K
D
S
Q
C
L
H
V
E
E
Site 37
T364
L
H
G
L
R
E
E
T
S
A
H
I
E
R
K
Site 38
S365
H
G
L
R
E
E
T
S
A
H
I
E
R
K
D
Site 39
T376
E
R
K
D
K
D
I
T
I
L
Q
C
R
L
Q
Site 40
T392
L
Q
L
E
F
T
E
T
Q
K
L
T
L
K
K
Site 41
T418
Q
E
L
E
K
K
L
T
Q
V
Q
N
S
L
L
Site 42
T444
M
A
T
E
L
E
M
T
V
K
E
A
K
Q
D
Site 43
S453
K
E
A
K
Q
D
K
S
K
E
A
E
C
K
A
Site 44
T508
A
G
C
H
L
E
D
T
Q
R
K
L
Q
K
G
Site 45
S541
Q
M
L
Q
K
E
S
S
M
A
E
K
E
Q
T
Site 46
T548
S
M
A
E
K
E
Q
T
S
N
R
K
R
V
E
Site 47
S549
M
A
E
K
E
Q
T
S
N
R
K
R
V
E
E
Site 48
S558
R
K
R
V
E
E
L
S
L
E
L
S
E
A
L
Site 49
S562
E
E
L
S
L
E
L
S
E
A
L
R
K
L
E
Site 50
S571
A
L
R
K
L
E
N
S
D
K
E
K
R
Q
L
Site 51
T581
E
K
R
Q
L
Q
K
T
V
A
E
Q
D
M
K
Site 52
S631
K
R
E
Q
L
K
K
S
K
E
H
E
K
L
M
Site 53
T655
E
F
K
K
K
D
K
T
L
K
E
N
S
R
K
Site 54
S678
R
A
E
L
Q
C
C
S
T
Q
L
E
S
S
L
Site 55
T679
A
E
L
Q
C
C
S
T
Q
L
E
S
S
L
N
Site 56
S684
C
S
T
Q
L
E
S
S
L
N
K
Y
N
T
S
Site 57
Y688
L
E
S
S
L
N
K
Y
N
T
S
Q
Q
V
I
Site 58
S691
S
L
N
K
Y
N
T
S
Q
Q
V
I
Q
D
L
Site 59
S708
E
I
A
L
Q
K
E
S
L
M
S
L
Q
A
Q
Site 60
S711
L
Q
K
E
S
L
M
S
L
Q
A
Q
L
D
K
Site 61
S740
K
E
A
Y
D
A
L
S
R
K
S
A
A
C
Q
Site 62
S743
Y
D
A
L
S
R
K
S
A
A
C
Q
D
D
L
Site 63
T751
A
A
C
Q
D
D
L
T
Q
A
L
E
K
L
N
Site 64
S762
E
K
L
N
H
V
T
S
E
T
K
S
L
Q
Q
Site 65
S766
H
V
T
S
E
T
K
S
L
Q
Q
S
L
T
Q
Site 66
S770
E
T
K
S
L
Q
Q
S
L
T
Q
T
Q
E
K
Site 67
T772
K
S
L
Q
Q
S
L
T
Q
T
Q
E
K
K
A
Site 68
T774
L
Q
Q
S
L
T
Q
T
Q
E
K
K
A
Q
L
Site 69
Y788
L
E
E
E
I
I
A
Y
E
E
R
M
K
K
L
Site 70
T797
E
R
M
K
K
L
N
T
E
L
R
K
L
R
G
Site 71
Y885
P
K
D
T
C
R
L
Y
R
G
N
D
Q
I
M
Site 72
Y919
Q
L
R
E
Q
V
K
Y
I
A
K
L
S
G
E
Site 73
T962
A
E
N
T
R
L
C
T
K
A
L
G
P
S
R
Site 74
S972
L
G
P
S
R
T
E
S
T
Q
R
E
K
V
C
Site 75
T973
G
P
S
R
T
E
S
T
Q
R
E
K
V
C
G
Site 76
Y1000
Q
R
M
D
L
T
K
Y
I
G
M
P
H
C
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation