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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KM-HN-1
Full Name:
Coiled-coil domain-containing protein 110
Alias:
Cancer/testis antigen 52; CC110; Coiled-coil domain containing 110; CT52; MGC33607
Type:
Uncharacterized protein
Mass (Da):
96726
Number AA:
833
UniProt ID:
Q8TBZ0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
R
E
E
D
E
V
D
S
V
L
L
S
A
S
K
Site 2
S27
A
S
K
I
L
N
S
S
E
G
V
K
E
S
G
Site 3
S33
S
S
E
G
V
K
E
S
G
C
S
D
T
E
Y
Site 4
S36
G
V
K
E
S
G
C
S
D
T
E
Y
G
C
I
Site 5
T38
K
E
S
G
C
S
D
T
E
Y
G
C
I
A
E
Site 6
Y40
S
G
C
S
D
T
E
Y
G
C
I
A
E
S
E
Site 7
S54
E
N
Q
I
Q
P
Q
S
A
L
K
V
L
Q
Q
Site 8
S65
V
L
Q
Q
Q
L
E
S
F
Q
A
L
R
M
Q
Site 9
S78
M
Q
T
L
Q
N
V
S
M
V
Q
S
E
I
S
Site 10
S82
Q
N
V
S
M
V
Q
S
E
I
S
E
I
L
N
Site 11
S91
I
S
E
I
L
N
K
S
I
I
E
V
E
N
P
Site 12
T118
R
I
E
K
D
L
P
T
E
N
Q
E
E
N
L
Site 13
S126
E
N
Q
E
E
N
L
S
M
E
K
S
H
H
F
Site 14
S130
E
N
L
S
M
E
K
S
H
H
F
E
D
S
K
Site 15
S136
K
S
H
H
F
E
D
S
K
T
L
H
S
V
E
Site 16
T138
H
H
F
E
D
S
K
T
L
H
S
V
E
E
K
Site 17
S141
E
D
S
K
T
L
H
S
V
E
E
K
L
S
G
Site 18
S147
H
S
V
E
E
K
L
S
G
D
S
V
N
S
L
Site 19
S150
E
E
K
L
S
G
D
S
V
N
S
L
P
Q
S
Site 20
S153
L
S
G
D
S
V
N
S
L
P
Q
S
V
N
V
Site 21
S157
S
V
N
S
L
P
Q
S
V
N
V
P
S
Q
I
Site 22
S162
P
Q
S
V
N
V
P
S
Q
I
H
S
E
D
T
Site 23
S166
N
V
P
S
Q
I
H
S
E
D
T
L
T
L
R
Site 24
T169
S
Q
I
H
S
E
D
T
L
T
L
R
T
S
T
Site 25
T171
I
H
S
E
D
T
L
T
L
R
T
S
T
D
N
Site 26
S175
D
T
L
T
L
R
T
S
T
D
N
L
S
S
N
Site 27
T176
T
L
T
L
R
T
S
T
D
N
L
S
S
N
I
Site 28
S180
R
T
S
T
D
N
L
S
S
N
I
I
I
H
P
Site 29
S181
T
S
T
D
N
L
S
S
N
I
I
I
H
P
S
Site 30
Y197
N
S
D
I
L
K
N
Y
N
N
F
Y
R
F
L
Site 31
T206
N
F
Y
R
F
L
P
T
A
P
P
N
V
M
S
Site 32
T217
N
V
M
S
Q
A
D
T
V
I
L
D
K
S
K
Site 33
S255
M
K
E
E
L
Q
K
S
H
D
G
E
V
A
L
Site 34
T263
H
D
G
E
V
A
L
T
N
E
L
Q
T
L
Q
Site 35
Y281
D
V
H
R
N
G
K
Y
D
M
S
P
I
H
Q
Site 36
S284
R
N
G
K
Y
D
M
S
P
I
H
Q
D
K
M
Site 37
S309
N
L
N
E
D
I
K
S
K
R
I
S
E
L
E
Site 38
S313
D
I
K
S
K
R
I
S
E
L
E
A
L
V
K
Site 39
T328
K
L
L
P
F
R
E
T
V
S
K
F
H
V
H
Site 40
S344
C
R
K
C
K
K
L
S
K
S
E
M
H
R
G
Site 41
S346
K
C
K
K
L
S
K
S
E
M
H
R
G
K
K
Site 42
T364
N
N
K
E
I
P
I
T
G
K
N
I
T
D
L
Site 43
T369
P
I
T
G
K
N
I
T
D
L
K
F
H
S
R
Site 44
Y380
F
H
S
R
V
P
R
Y
T
L
S
F
L
D
Q
Site 45
T381
H
S
R
V
P
R
Y
T
L
S
F
L
D
Q
T
Site 46
S383
R
V
P
R
Y
T
L
S
F
L
D
Q
T
K
H
Site 47
S406
P
F
L
V
K
Q
G
S
I
I
S
E
N
E
K
Site 48
S409
V
K
Q
G
S
I
I
S
E
N
E
K
T
S
K
Site 49
T414
I
I
S
E
N
E
K
T
S
K
V
N
S
V
T
Site 50
S419
E
K
T
S
K
V
N
S
V
T
E
Q
C
V
A
Site 51
Y434
K
I
Q
Y
L
Q
N
Y
L
K
E
S
V
Q
I
Site 52
S457
S
E
N
L
N
L
K
S
K
M
K
P
L
I
F
Site 53
T465
K
M
K
P
L
I
F
T
T
Q
S
L
I
Q
K
Site 54
T466
M
K
P
L
I
F
T
T
Q
S
L
I
Q
K
V
Site 55
S468
P
L
I
F
T
T
Q
S
L
I
Q
K
V
E
T
Site 56
S488
K
N
L
V
E
E
K
S
T
I
Q
S
K
L
S
Site 57
T489
N
L
V
E
E
K
S
T
I
Q
S
K
L
S
K
Site 58
S492
E
E
K
S
T
I
Q
S
K
L
S
K
T
E
E
Site 59
S495
S
T
I
Q
S
K
L
S
K
T
E
E
Y
S
K
Site 60
S513
K
E
F
K
K
I
I
S
K
Y
N
V
L
Q
G
Site 61
Y515
F
K
K
I
I
S
K
Y
N
V
L
Q
G
Q
N
Site 62
T524
V
L
Q
G
Q
N
K
T
L
E
E
K
N
I
Q
Site 63
S533
E
E
K
N
I
Q
L
S
L
E
K
Q
Q
M
M
Site 64
S548
E
A
L
D
Q
L
K
S
K
E
H
K
T
Q
S
Site 65
T553
L
K
S
K
E
H
K
T
Q
S
D
M
A
I
V
Site 66
S555
S
K
E
H
K
T
Q
S
D
M
A
I
V
N
N
Site 67
S600
H
Q
L
L
K
E
K
S
S
L
G
N
E
L
K
Site 68
S601
Q
L
L
K
E
K
S
S
L
G
N
E
L
K
E
Site 69
S609
L
G
N
E
L
K
E
S
Q
L
E
I
I
Q
L
Site 70
T625
E
K
E
R
L
A
K
T
E
Q
E
T
L
L
Q
Site 71
T629
L
A
K
T
E
Q
E
T
L
L
Q
I
I
E
T
Site 72
T636
T
L
L
Q
I
I
E
T
V
K
D
E
K
L
N
Site 73
T647
E
K
L
N
L
E
T
T
L
Q
E
S
T
A
A
Site 74
T667
R
E
I
E
N
I
Q
T
Y
Q
S
T
A
E
E
Site 75
Y668
E
I
E
N
I
Q
T
Y
Q
S
T
A
E
E
N
Site 76
S670
E
N
I
Q
T
Y
Q
S
T
A
E
E
N
F
L
Site 77
S685
Q
E
I
K
N
A
K
S
E
A
S
I
Y
K
N
Site 78
Y690
A
K
S
E
A
S
I
Y
K
N
S
L
S
E
I
Site 79
S693
E
A
S
I
Y
K
N
S
L
S
E
I
G
K
E
Site 80
S695
S
I
Y
K
N
S
L
S
E
I
G
K
E
C
E
Site 81
T713
K
M
V
M
E
T
K
T
D
N
Q
I
L
K
E
Site 82
S735
E
N
I
K
F
E
N
S
I
S
R
L
T
E
D
Site 83
S737
I
K
F
E
N
S
I
S
R
L
T
E
D
K
I
Site 84
T740
E
N
S
I
S
R
L
T
E
D
K
I
L
L
E
Site 85
Y749
D
K
I
L
L
E
N
Y
V
R
S
I
E
N
E
Site 86
T759
S
I
E
N
E
R
D
T
L
E
F
E
M
R
H
Site 87
Y771
M
R
H
L
Q
R
E
Y
L
S
L
S
D
K
I
Site 88
S773
H
L
Q
R
E
Y
L
S
L
S
D
K
I
C
N
Site 89
S775
Q
R
E
Y
L
S
L
S
D
K
I
C
N
Q
H
Site 90
T788
Q
H
N
D
P
S
K
T
T
Y
I
S
R
R
E
Site 91
Y790
N
D
P
S
K
T
T
Y
I
S
R
R
E
K
F
Site 92
S792
P
S
K
T
T
Y
I
S
R
R
E
K
F
H
F
Site 93
Y802
E
K
F
H
F
D
N
Y
T
H
E
D
T
S
S
Site 94
T803
K
F
H
F
D
N
Y
T
H
E
D
T
S
S
P
Site 95
T807
D
N
Y
T
H
E
D
T
S
S
P
Q
S
R
P
Site 96
S808
N
Y
T
H
E
D
T
T
S
P
Q
S
R
P
L
Site 97
S809
Y
T
H
E
D
T
S
S
P
Q
S
R
P
L
A
Site 98
S812
E
D
T
S
S
P
Q
S
R
P
L
A
S
D
L
Site 99
S817
P
Q
S
R
P
L
A
S
D
L
K
G
Y
F
K
Site 100
Y822
L
A
S
D
L
K
G
Y
F
K
V
K
D
R
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation