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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WDR51B
Full Name:
POC1 centriolar protein homolog B
Alias:
TUWD12; WD repeat domain 51B; WD51B
Type:
Mass (Da):
53668
Number AA:
478
UniProt ID:
Q8TC44
International Prot ID:
IPI00152269
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y13
E
D
P
V
L
E
R
Y
F
K
G
H
K
A
A
Site 2
S23
G
H
K
A
A
I
T
S
L
D
L
S
P
N
G
Site 3
S27
A
I
T
S
L
D
L
S
P
N
G
K
Q
L
A
Site 4
Y54
F
K
P
H
A
R
A
Y
R
Y
V
G
H
K
D
Site 5
Y56
P
H
A
R
A
Y
R
Y
V
G
H
K
D
V
V
Site 6
T64
V
G
H
K
D
V
V
T
S
V
Q
F
S
P
H
Site 7
S65
G
H
K
D
V
V
T
S
V
Q
F
S
P
H
G
Site 8
S77
P
H
G
N
L
L
A
S
A
S
R
D
R
T
V
Site 9
S79
G
N
L
L
A
S
A
S
R
D
R
T
V
R
L
Site 10
T83
A
S
A
S
R
D
R
T
V
R
L
W
I
P
D
Site 11
S107
A
H
T
A
P
V
R
S
V
D
F
S
A
D
G
Site 12
S121
G
Q
F
L
A
T
A
S
E
D
K
S
I
K
V
Site 13
S125
A
T
A
S
E
D
K
S
I
K
V
W
S
M
Y
Site 14
Y132
S
I
K
V
W
S
M
Y
R
Q
R
F
L
Y
S
Site 15
Y138
M
Y
R
Q
R
F
L
Y
S
L
Y
R
H
T
H
Site 16
S161
P
D
G
R
L
I
V
S
C
S
E
D
K
T
I
Site 17
S163
G
R
L
I
V
S
C
S
E
D
K
T
I
K
I
Site 18
T167
V
S
C
S
E
D
K
T
I
K
I
W
D
T
T
Site 19
S203
P
S
G
T
C
I
A
S
A
G
S
D
Q
T
V
Site 20
T209
A
S
A
G
S
D
Q
T
V
K
V
W
D
V
R
Site 21
Y224
V
N
K
L
L
Q
H
Y
Q
V
H
S
G
G
V
Site 22
S235
S
G
G
V
N
C
I
S
F
H
P
S
G
N
Y
Site 23
Y242
S
F
H
P
S
G
N
Y
L
I
T
A
S
S
D
Site 24
T245
P
S
G
N
Y
L
I
T
A
S
S
D
G
T
L
Site 25
T265
L
E
G
R
L
I
Y
T
L
Q
G
H
T
G
P
Site 26
T275
G
H
T
G
P
V
F
T
V
S
F
S
K
G
G
Site 27
S287
K
G
G
E
L
F
A
S
G
G
A
D
T
Q
V
Site 28
T310
E
L
H
C
K
G
L
T
K
R
N
L
K
R
L
Site 29
S321
L
K
R
L
H
F
D
S
P
P
H
L
L
D
I
Site 30
Y329
P
P
H
L
L
D
I
Y
P
R
T
P
H
P
H
Site 31
T332
L
L
D
I
Y
P
R
T
P
H
P
H
E
E
K
Site 32
T342
P
H
E
E
K
V
E
T
V
E
I
N
P
K
L
Site 33
S369
M
D
I
L
S
F
D
S
T
T
T
T
E
T
S
Site 34
T370
D
I
L
S
F
D
S
T
T
T
T
E
T
S
G
Site 35
T371
I
L
S
F
D
S
T
T
T
T
E
T
S
G
R
Site 36
T373
S
F
D
S
T
T
T
T
E
T
S
G
R
T
L
Site 37
S376
S
T
T
T
T
E
T
S
G
R
T
L
P
D
K
Site 38
Y390
K
G
E
E
A
C
G
Y
F
L
N
P
S
L
M
Site 39
T404
M
S
P
E
C
L
P
T
T
T
K
K
K
T
E
Site 40
T405
S
P
E
C
L
P
T
T
T
K
K
K
T
E
D
Site 41
T410
P
T
T
T
K
K
K
T
E
D
M
S
D
L
P
Site 42
S414
K
K
K
T
E
D
M
S
D
L
P
C
E
S
Q
Site 43
S420
M
S
D
L
P
C
E
S
Q
R
S
I
P
L
A
Site 44
T445
Q
L
N
V
L
T
Q
T
V
S
I
L
E
Q
R
Site 45
T454
S
I
L
E
Q
R
L
T
L
T
E
D
K
L
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation