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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM110B
Full Name:
Protein FAM110B
Alias:
C8orf72; Family with sequence similarity 110B
Type:
Uncharacterized cytoplasmic and centrosomal protein. FAM110 family.
Mass (Da):
40728
Number AA:
370
UniProt ID:
Q8TC76
International Prot ID:
IPI00478176
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005739
GO:0005813
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
P
T
E
T
L
Q
T
G
S
M
V
K
P
V
Site 2
S16
G
S
M
V
K
P
V
S
P
A
G
T
F
T
S
Site 3
Y36
I
L
N
K
G
P
D
Y
F
R
R
Q
A
E
P
Site 4
S49
E
P
N
P
K
R
L
S
A
V
E
R
L
E
A
Site 5
Y61
L
E
A
D
K
A
K
Y
V
K
S
Q
E
V
I
Site 6
S64
D
K
A
K
Y
V
K
S
Q
E
V
I
N
A
K
Site 7
S95
A
A
K
R
A
L
G
S
P
T
L
K
V
F
G
Site 8
T97
K
R
A
L
G
S
P
T
L
K
V
F
G
N
H
Site 9
T107
V
F
G
N
H
A
K
T
E
S
G
V
Q
R
E
Site 10
S127
I
L
K
N
I
I
N
S
S
E
G
S
S
S
G
Site 11
S128
L
K
N
I
I
N
S
S
E
G
S
S
S
G
S
Site 12
S131
I
I
N
S
S
E
G
S
S
S
G
S
G
H
K
Site 13
S132
I
N
S
S
E
G
S
S
S
G
S
G
H
K
H
Site 14
S133
N
S
S
E
G
S
S
S
G
S
G
H
K
H
S
Site 15
S135
S
E
G
S
S
S
G
S
G
H
K
H
S
S
R
Site 16
S140
S
G
S
G
H
K
H
S
S
R
N
W
P
P
H
Site 17
S141
G
S
G
H
K
H
S
S
R
N
W
P
P
H
R
Site 18
S149
R
N
W
P
P
H
R
S
E
A
T
D
L
H
R
Site 19
S158
A
T
D
L
H
R
H
S
F
A
E
S
L
K
V
Site 20
S162
H
R
H
S
F
A
E
S
L
K
V
Y
P
T
Q
Site 21
Y166
F
A
E
S
L
K
V
Y
P
T
Q
G
R
R
S
Site 22
T168
E
S
L
K
V
Y
P
T
Q
G
R
R
S
P
Q
Site 23
S173
Y
P
T
Q
G
R
R
S
P
Q
E
G
G
S
H
Site 24
S189
G
R
R
L
L
E
Q
S
A
E
S
F
L
H
V
Site 25
S192
L
L
E
Q
S
A
E
S
F
L
H
V
S
H
S
Site 26
S197
A
E
S
F
L
H
V
S
H
S
S
S
D
I
R
Site 27
S199
S
F
L
H
V
S
H
S
S
S
D
I
R
K
V
Site 28
S201
L
H
V
S
H
S
S
S
D
I
R
K
V
T
S
Site 29
T207
S
S
D
I
R
K
V
T
S
V
K
P
L
K
A
Site 30
S208
S
D
I
R
K
V
T
S
V
K
P
L
K
A
I
Site 31
S220
K
A
I
P
C
S
S
S
A
P
P
L
P
P
K
Site 32
S235
P
K
I
A
A
I
A
S
M
K
S
P
E
A
D
Site 33
S238
A
A
I
A
S
M
K
S
P
E
A
D
P
V
E
Site 34
S251
V
E
P
A
C
G
V
S
R
R
P
S
L
Q
R
Site 35
S255
C
G
V
S
R
R
P
S
L
Q
R
S
K
S
D
Site 36
S259
R
R
P
S
L
Q
R
S
K
S
D
L
S
D
R
Site 37
S261
P
S
L
Q
R
S
K
S
D
L
S
D
R
Y
F
Site 38
S264
Q
R
S
K
S
D
L
S
D
R
Y
F
R
V
D
Site 39
Y267
K
S
D
L
S
D
R
Y
F
R
V
D
A
D
V
Site 40
S301
E
N
F
A
R
A
N
S
D
I
I
S
L
N
F
Site 41
S305
R
A
N
S
D
I
I
S
L
N
F
R
S
A
S
Site 42
S312
S
L
N
F
R
S
A
S
M
I
S
S
D
C
E
Site 43
S316
R
S
A
S
M
I
S
S
D
C
E
Q
S
Q
D
Site 44
S321
I
S
S
D
C
E
Q
S
Q
D
S
N
S
D
L
Site 45
S324
D
C
E
Q
S
Q
D
S
N
S
D
L
R
N
D
Site 46
S326
E
Q
S
Q
D
S
N
S
D
L
R
N
D
D
S
Site 47
S333
S
D
L
R
N
D
D
S
A
N
D
R
V
P
Y
Site 48
Y340
S
A
N
D
R
V
P
Y
G
I
S
A
I
E
R
Site 49
S357
R
I
I
K
W
L
Y
S
I
K
Q
A
R
E
S
Site 50
S364
S
I
K
Q
A
R
E
S
Q
K
V
S
H
V
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation