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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PIG38
Full Name:
Ecto-NOX disulfide-thiol exchanger 1
Alias:
BA64J21.1; Candidate growth-related and time keeping constitutive hydroquinone [NADH] oxidase; CCNOX; Cell proliferation-inducing gene 38 protein; CNOX; Constitutive Ecto-NOX; ENOX1; FLJ10094; Proliferation-inducing protein 38; RP11-301I17.1
Type:
EC 1.-.-.-; Oxidoreductase; RNA binding protein
Mass (Da):
73348
Number AA:
643
UniProt ID:
Q8TC92
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005615
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005507
GO:0003676
GO:0000166
PhosphoSite+
KinaseNET
Biological Process:
GO:0022900
GO:0048511
GO:0006810
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
A
G
G
V
E
N
I
T
Q
L
P
Q
E
L
P
Site 2
S41
D
T
T
Q
L
N
M
S
V
T
D
P
T
A
W
Site 3
S133
N
P
N
L
P
P
P
S
T
R
E
R
P
P
G
Site 4
T134
P
N
L
P
P
P
S
T
R
E
R
P
P
G
C
Site 5
T143
E
R
P
P
G
C
K
T
V
F
V
G
G
L
P
Site 6
T169
F
E
Q
C
G
D
I
T
A
I
R
K
S
K
K
Site 7
Y194
F
M
V
D
K
A
I
Y
L
S
G
Y
R
M
R
Site 8
S196
V
D
K
A
I
Y
L
S
G
Y
R
M
R
L
G
Site 9
Y198
K
A
I
Y
L
S
G
Y
R
M
R
L
G
S
S
Site 10
S204
G
Y
R
M
R
L
G
S
S
T
D
K
K
D
S
Site 11
S205
Y
R
M
R
L
G
S
S
T
D
K
K
D
S
G
Site 12
T206
R
M
R
L
G
S
S
T
D
K
K
D
S
G
R
Site 13
S211
S
S
T
D
K
K
D
S
G
R
L
H
V
D
F
Site 14
Y226
A
Q
A
R
D
D
F
Y
E
W
E
C
K
Q
R
Site 15
S254
E
D
R
L
R
P
P
S
P
P
A
I
M
H
Y
Site 16
S299
R
G
E
V
N
R
R
S
A
N
Q
F
Y
S
M
Site 17
Y304
R
R
S
A
N
Q
F
Y
S
M
V
Q
S
A
N
Site 18
S305
R
S
A
N
Q
F
Y
S
M
V
Q
S
A
N
S
Site 19
S309
Q
F
Y
S
M
V
Q
S
A
N
S
H
V
R
R
Site 20
S312
S
M
V
Q
S
A
N
S
H
V
R
R
L
M
N
Site 21
S380
I
D
I
W
R
K
H
S
E
E
L
R
N
A
Q
Site 22
S388
E
E
L
R
N
A
Q
S
E
Q
L
M
G
I
R
Site 23
S403
R
E
E
E
M
E
M
S
D
D
E
N
C
D
S
Site 24
S410
S
D
D
E
N
C
D
S
P
T
K
K
M
R
V
Site 25
T412
D
E
N
C
D
S
P
T
K
K
M
R
V
D
E
Site 26
S435
A
L
K
E
E
N
D
S
L
R
W
Q
L
D
A
Site 27
Y443
L
R
W
Q
L
D
A
Y
R
N
E
V
E
L
L
Site 28
T465
F
R
T
E
E
N
L
T
K
D
Q
Q
L
Q
F
Site 29
T486
G
M
Q
Q
Q
L
L
T
I
Q
E
E
L
N
N
Site 30
S496
E
E
L
N
N
K
K
S
E
L
E
Q
A
K
E
Site 31
S506
E
Q
A
K
E
E
Q
S
H
T
Q
A
L
L
K
Site 32
T508
A
K
E
E
Q
S
H
T
Q
A
L
L
K
V
L
Site 33
T528
G
T
K
E
L
V
E
T
N
G
H
S
H
E
D
Site 34
S532
L
V
E
T
N
G
H
S
H
E
D
S
N
E
I
Site 35
S536
N
G
H
S
H
E
D
S
N
E
I
N
V
L
T
Site 36
S559
E
N
N
I
E
K
R
S
Q
G
L
K
S
E
K
Site 37
S564
K
R
S
Q
G
L
K
S
E
K
E
A
L
L
I
Site 38
Y589
P
F
G
A
N
I
E
Y
L
W
S
Y
M
Q
Q
Site 39
Y593
N
I
E
Y
L
W
S
Y
M
Q
Q
L
D
S
K
Site 40
S599
S
Y
M
Q
Q
L
D
S
K
I
S
A
N
E
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation