PhosphoNET

           
Protein Info 
   
Short Name:  FNDC8
Full Name:  Fibronectin type III domain-containing protein 8
Alias: 
Type: 
Mass (Da):  35921
Number AA:  324
UniProt ID:  Q8TC99
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S36DQLPKPFSNPKSMNR
Site 2S40KPFSNPKSMNRTVTT
Site 3T44NPKSMNRTVTTKGLP
Site 4T46KSMNRTVTTKGLPLA
Site 5S78KPLPVEDSDCSSDET
Site 6S81PVEDSDCSSDETSIS
Site 7S82VEDSDCSSDETSISA
Site 8T85SDCSSDETSISAFSS
Site 9S86DCSSDETSISAFSST
Site 10S88SSDETSISAFSSTLL
Site 11T103NPIKLAVTQPNSSFF
Site 12S122EGELNKLSFSPMAKN
Site 13S124ELNKLSFSPMAKNAE
Site 14S144LGPCPCPSKSQMATR
Site 15S146PCPCPSKSQMATRGL
Site 16T150PSKSQMATRGLLDLD
Site 17T163LDNPELETETSSTHS
Site 18S166PELETETSSTHSESS
Site 19S167ELETETSSTHSESSV
Site 20T168LETETSSTHSESSVV
Site 21S170TETSSTHSESSVVVD
Site 22S172TSSTHSESSVVVDLP
Site 23S173SSTHSESSVVVDLPD
Site 24T193EHTVNNSTAVISWTY
Site 25T220LLQEVAKTQENELPE
Site 26Y273VGKWCKPYKFATLAT
Site 27S283ATLATDFSSFPENYP
Site 28S284TLATDFSSFPENYPI
Site 29Y289FSSFPENYPIQITVR
Site 30T294ENYPIQITVRRKEPR
Site 31S306EPRQKIVSIGPEEMR
Site 32Y320RRLEDLEYLFPC___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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