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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CPT1C
Full Name:
Carnitine O-palmitoyltransferase 1, brain isoform
Alias:
CPT IC;Carnitine O-palmitoyltransferase I, brain isoform;Carnitine palmitoyltransferase 1C
Type:
Mass (Da):
90989
Number AA:
803
UniProt ID:
Q8TCG5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
Q
A
V
G
F
R
P
S
L
T
S
D
G
A
E
Site 2
S16
G
F
R
P
S
L
T
S
D
G
A
E
V
E
L
Site 3
S34
V
L
Q
E
I
Y
L
S
G
L
R
S
W
K
R
Site 4
S38
I
Y
L
S
G
L
R
S
W
K
R
H
L
S
R
Site 5
T52
R
F
W
N
D
F
L
T
G
V
F
P
A
S
P
Site 6
S145
E
P
H
G
A
M
S
S
P
T
K
T
W
L
A
Site 7
S166
G
R
H
P
M
L
F
S
Y
Q
R
S
L
P
R
Site 8
Y167
R
H
P
M
L
F
S
Y
Q
R
S
L
P
R
Q
Site 9
S170
M
L
F
S
Y
Q
R
S
L
P
R
Q
P
V
P
Site 10
S178
L
P
R
Q
P
V
P
S
V
Q
D
T
V
R
K
Site 11
T182
P
V
P
S
V
Q
D
T
V
R
K
Y
L
E
S
Site 12
Y186
V
Q
D
T
V
R
K
Y
L
E
S
V
R
P
I
Site 13
S189
T
V
R
K
Y
L
E
S
V
R
P
I
L
S
D
Site 14
S195
E
S
V
R
P
I
L
S
D
E
D
F
D
W
T
Site 15
T202
S
D
E
D
F
D
W
T
A
V
L
A
Q
E
F
Site 16
S215
E
F
L
R
L
Q
A
S
L
L
Q
W
Y
L
R
Site 17
Y220
Q
A
S
L
L
Q
W
Y
L
R
L
K
S
W
W
Site 18
Y241
D
W
W
E
E
F
V
Y
L
R
S
R
N
P
L
Site 19
Y282
A
V
H
A
L
L
L
Y
R
H
R
L
N
R
Q
Site 20
T294
N
R
Q
E
I
P
P
T
L
L
M
G
M
R
P
Site 21
Y307
R
P
L
C
S
A
Q
Y
E
K
I
F
N
T
T
Site 22
T313
Q
Y
E
K
I
F
N
T
T
R
I
P
G
V
Q
Site 23
Y323
I
P
G
V
Q
K
D
Y
I
R
H
L
H
D
S
Site 24
T346
G
R
F
F
R
M
G
T
H
S
R
N
S
L
L
Site 25
S348
F
F
R
M
G
T
H
S
R
N
S
L
L
S
P
Site 26
S351
M
G
T
H
S
R
N
S
L
L
S
P
R
A
L
Site 27
S354
H
S
R
N
S
L
L
S
P
R
A
L
E
Q
Q
Site 28
S370
Q
R
I
L
D
D
P
S
P
A
C
P
H
E
E
Site 29
T383
E
E
H
L
A
A
L
T
A
A
P
R
G
T
W
Site 30
T389
L
T
A
A
P
R
G
T
W
A
Q
V
R
T
S
Site 31
S396
T
W
A
Q
V
R
T
S
L
K
T
Q
A
A
E
Site 32
T399
Q
V
R
T
S
L
K
T
Q
A
A
E
A
L
E
Site 33
T455
R
W
F
D
K
S
F
T
L
I
V
F
S
N
G
Site 34
S467
S
N
G
K
L
G
L
S
V
E
H
S
W
A
D
Site 35
Y495
T
E
C
F
Q
L
G
Y
S
T
D
G
H
C
K
Site 36
T508
C
K
G
H
P
D
P
T
L
P
Q
P
Q
R
L
Site 37
S528
D
Q
I
H
S
S
I
S
L
A
L
R
G
A
K
Site 38
S538
L
R
G
A
K
I
L
S
E
N
V
D
C
H
V
Site 39
S563
I
R
R
C
H
L
S
S
D
S
F
I
Q
I
A
Site 40
T585
D
R
G
Q
F
C
L
T
Y
E
S
A
M
T
R
Site 41
Y586
R
G
Q
F
C
L
T
Y
E
S
A
M
T
R
L
Site 42
T591
L
T
Y
E
S
A
M
T
R
L
F
L
E
G
R
Site 43
T601
F
L
E
G
R
T
E
T
V
R
S
C
T
R
E
Site 44
S604
G
R
T
E
T
V
R
S
C
T
R
E
A
C
N
Site 45
T606
T
E
T
V
R
S
C
T
R
E
A
C
N
F
V
Site 46
T622
A
M
E
D
K
E
K
T
D
P
Q
C
L
A
L
Site 47
S646
A
L
L
K
A
A
M
S
G
Q
G
V
D
R
H
Site 48
S668
S
R
F
L
H
L
Q
S
P
F
L
T
Q
V
H
Site 49
T672
H
L
Q
S
P
F
L
T
Q
V
H
S
E
Q
W
Site 50
S676
P
F
L
T
Q
V
H
S
E
Q
W
Q
L
S
T
Site 51
S682
H
S
E
Q
W
Q
L
S
T
S
Q
I
P
V
Q
Site 52
S684
E
Q
W
Q
L
S
T
S
Q
I
P
V
Q
Q
M
Site 53
Y699
H
L
F
D
V
H
N
Y
P
D
Y
V
S
S
G
Site 54
Y702
D
V
H
N
Y
P
D
Y
V
S
S
G
G
G
F
Site 55
S704
H
N
Y
P
D
Y
V
S
S
G
G
G
F
G
P
Site 56
S705
N
Y
P
D
Y
V
S
S
G
G
G
F
G
P
A
Site 57
Y717
G
P
A
D
D
H
G
Y
G
V
S
Y
I
F
M
Site 58
Y721
D
H
G
Y
G
V
S
Y
I
F
M
G
D
G
M
Site 59
S734
G
M
I
T
F
H
I
S
S
K
K
S
S
T
K
Site 60
S735
M
I
T
F
H
I
S
S
K
K
S
S
T
K
T
Site 61
S738
F
H
I
S
S
K
K
S
S
T
K
T
D
S
H
Site 62
S739
H
I
S
S
K
K
S
S
T
K
T
D
S
H
R
Site 63
T740
I
S
S
K
K
S
S
T
K
T
D
S
H
R
L
Site 64
T742
S
K
K
S
S
T
K
T
D
S
H
R
L
G
Q
Site 65
S744
K
S
S
T
K
T
D
S
H
R
L
G
Q
H
I
Site 66
S775
F
K
R
R
F
R
G
S
G
K
E
N
S
R
H
Site 67
S780
R
G
S
G
K
E
N
S
R
H
R
C
G
F
L
Site 68
S788
R
H
R
C
G
F
L
S
R
Q
T
G
A
S
K
Site 69
T791
C
G
F
L
S
R
Q
T
G
A
S
K
A
S
M
Site 70
S794
L
S
R
Q
T
G
A
S
K
A
S
M
T
S
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation