PhosphoNET

           
Protein Info 
   
Short Name:  MARCH-I
Full Name:  E3 ubiquitin-protein ligase MARCH1
Alias:  Membrane-associated RING finger protein 1
Type: 
Mass (Da):  32290
Number AA:  289
UniProt ID:  Q8TCQ1
International Prot ID:  IPI00382922
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0012506  GO:0016020  GO:0016021 Uniprot OncoNet
Molecular Function:  GO:0003824  GO:0005488  GO:0008270 PhosphoSite+ KinaseNET
Biological Process:  GO:0006508  GO:0006511  GO:0008152 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T19PHRIPNNTRTPEISG
Site 2T21RIPNNTRTPEISGDL
Site 3S25NTRTPEISGDLADAS
Site 4S32SGDLADASQTSTLNE
Site 5T36ADASQTSTLNEKSPG
Site 6S41TSTLNEKSPGRSASR
Site 7S45NEKSPGRSASRSSNI
Site 8S47KSPGRSASRSSNISK
Site 9S49PGRSASRSSNISKAS
Site 10S50GRSASRSSNISKASS
Site 11S53ASRSSNISKASSPTT
Site 12S56SSNISKASSPTTGTA
Site 13S57SNISKASSPTTGTAP
Site 14T60SKASSPTTGTAPRSQ
Site 15T62ASSPTTGTAPRSQSR
Site 16S66TTGTAPRSQSRLSVC
Site 17S68GTAPRSQSRLSVCPS
Site 18S71PRSQSRLSVCPSTQD
Site 19S75SRLSVCPSTQDICRI
Site 20S91HCEGDEESPLITPCR
Site 21T95DEESPLITPCRCTGT
Site 22T102TPCRCTGTLRFVHQS
Site 23S150EKLQMTTSERRKIFC
Site 24Y232LWRRLKAYNRVIFVQ
Site 25T244FVQNCPDTAKKLEKN
Site 26S253KKLEKNFSCNVNTDI
Site 27S275VPQTGANSLPSAEGG
Site 28S278TGANSLPSAEGGPPE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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