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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RHPN1
Full Name:
Rhophilin-1
Alias:
GTP-Rho-binding protein 1; ODF5
Type:
Mass (Da):
76292
Number AA:
695
UniProt ID:
Q8TCX5
International Prot ID:
IPI00607856
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
G
A
G
A
G
E
E
S
P
R
L
Q
G
C
D
Site 2
S24
P
R
L
Q
G
C
D
S
L
T
Q
I
Q
C
G
Site 3
T26
L
Q
G
C
D
S
L
T
Q
I
Q
C
G
Q
L
Site 4
Y58
R
T
G
A
E
N
L
Y
R
A
T
S
N
N
R
Site 5
T61
A
E
N
L
Y
R
A
T
S
N
N
R
V
R
E
Site 6
S62
E
N
L
Y
R
A
T
S
N
N
R
V
R
E
T
Site 7
T69
S
N
N
R
V
R
E
T
V
A
L
E
L
S
Y
Site 8
S75
E
T
V
A
L
E
L
S
Y
V
N
S
N
L
Q
Site 9
S79
L
E
L
S
Y
V
N
S
N
L
Q
L
L
K
E
Site 10
S102
V
D
P
G
R
H
G
S
E
A
V
T
V
P
M
Site 11
S123
E
T
K
E
L
D
W
S
T
P
L
K
E
L
I
Site 12
T124
T
K
E
L
D
W
S
T
P
L
K
E
L
I
S
Site 13
S131
T
P
L
K
E
L
I
S
V
H
F
G
E
D
G
Site 14
S140
H
F
G
E
D
G
A
S
Y
E
A
E
I
R
E
Site 15
Y141
F
G
E
D
G
A
S
Y
E
A
E
I
R
E
L
Site 16
T157
A
L
R
Q
A
M
R
T
P
S
R
N
E
S
G
Site 17
S159
R
Q
A
M
R
T
P
S
R
N
E
S
G
L
E
Site 18
S163
R
T
P
S
R
N
E
S
G
L
E
L
L
T
A
Site 19
T200
F
H
W
Y
D
S
L
T
G
V
P
A
Q
Q
R
Site 20
S234
I
G
A
R
Q
D
R
S
C
T
E
G
A
R
R
Site 21
T236
A
R
Q
D
R
S
C
T
E
G
A
R
R
A
M
Site 22
S254
Q
R
A
A
G
A
F
S
L
L
R
E
N
F
S
Site 23
S261
S
L
L
R
E
N
F
S
H
A
P
S
P
D
M
Site 24
S265
E
N
F
S
H
A
P
S
P
D
M
S
A
A
S
Site 25
S297
E
G
L
S
P
P
A
S
M
A
P
Q
D
C
L
Site 26
T326
E
Y
R
L
V
H
R
T
M
A
Q
P
P
V
H
Site 27
Y335
A
Q
P
P
V
H
D
Y
V
P
V
S
W
T
A
Site 28
Y350
L
V
H
V
K
A
E
Y
F
R
S
L
A
H
Y
Site 29
S353
V
K
A
E
Y
F
R
S
L
A
H
Y
H
V
A
Site 30
S367
A
M
A
L
C
D
G
S
R
E
C
P
P
H
L
Site 31
S386
P
R
P
P
R
A
G
S
Q
P
L
C
P
P
A
Site 32
S412
V
F
L
Q
P
P
T
S
S
K
P
R
G
P
V
Site 33
S413
F
L
Q
P
P
T
S
S
K
P
R
G
P
V
L
Site 34
T468
L
R
A
V
I
S
Q
T
L
Q
R
S
L
A
K
Site 35
S472
I
S
Q
T
L
Q
R
S
L
A
K
Y
A
E
L
Site 36
Y476
L
Q
R
S
L
A
K
Y
A
E
L
D
R
E
D
Site 37
T498
A
P
D
I
Q
P
K
T
H
Q
K
P
E
A
R
Site 38
S510
E
A
R
M
P
R
L
S
Q
G
K
G
P
D
I
Site 39
S525
F
H
R
L
G
P
L
S
V
F
S
A
K
N
R
Site 40
T551
G
E
G
G
F
G
L
T
L
R
G
D
S
P
V
Site 41
Y579
A
G
L
K
E
G
D
Y
I
V
S
V
N
G
Q
Site 42
S582
K
E
G
D
Y
I
V
S
V
N
G
Q
P
C
R
Site 43
S623
L
P
S
S
R
L
P
S
L
G
D
R
R
P
V
Site 44
S640
G
P
R
G
L
L
R
S
Q
R
E
H
G
C
K
Site 45
T648
Q
R
E
H
G
C
K
T
P
A
S
T
W
A
S
Site 46
S651
H
G
C
K
T
P
A
S
T
W
A
S
P
R
P
Site 47
S655
T
P
A
S
T
W
A
S
P
R
P
L
L
N
W
Site 48
S687
P
V
K
P
A
P
P
S
S
L
K
H
P
G
W
Site 49
S688
V
K
P
A
P
P
S
S
L
K
H
P
G
W
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation