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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MIPOL1
Full Name:
Mirror-image polydactyly gene 1 protein
Alias:
Mirror-image polydactyly 1
Type:
Uncharacterized protein
Mass (Da):
51537
Number AA:
442
UniProt ID:
Q8TD10
International Prot ID:
IPI00413518
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0005634
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
E
N
W
S
K
D
I
T
H
S
Y
L
E
Q
E
Site 2
Y12
S
K
D
I
T
H
S
Y
L
E
Q
E
T
T
G
Site 3
T18
S
Y
L
E
Q
E
T
T
G
I
N
K
S
T
Q
Site 4
S23
E
T
T
G
I
N
K
S
T
Q
P
D
E
Q
L
Site 5
T31
T
Q
P
D
E
Q
L
T
M
N
S
E
K
S
M
Site 6
S37
L
T
M
N
S
E
K
S
M
H
R
K
S
T
E
Site 7
S42
E
K
S
M
H
R
K
S
T
E
L
V
N
E
I
Site 8
T43
K
S
M
H
R
K
S
T
E
L
V
N
E
I
T
Site 9
T62
E
W
P
G
Q
R
S
T
N
F
Q
I
I
S
S
Site 10
Y70
N
F
Q
I
I
S
S
Y
P
D
D
E
S
V
Y
Site 11
S75
S
S
Y
P
D
D
E
S
V
Y
C
T
T
E
K
Site 12
Y77
Y
P
D
D
E
S
V
Y
C
T
T
E
K
Y
N
Site 13
Y83
V
Y
C
T
T
E
K
Y
N
V
M
E
H
R
H
Site 14
S105
M
T
P
C
Q
V
T
S
D
S
D
K
E
K
T
Site 15
S107
P
C
Q
V
T
S
D
S
D
K
E
K
T
I
A
Site 16
T112
S
D
S
D
K
E
K
T
I
A
F
L
L
K
E
Site 17
S126
E
L
D
I
L
R
T
S
N
K
K
L
Q
Q
K
Site 18
Y171
A
A
L
V
E
E
V
Y
F
A
Q
K
E
R
D
Site 19
T220
N
P
E
E
N
D
M
T
L
Q
E
L
L
N
R
Site 20
Y249
A
I
I
V
D
R
I
Y
K
T
K
E
C
K
M
Site 21
T259
K
E
C
K
M
R
I
T
A
E
E
M
S
A
L
Site 22
S275
E
E
R
D
A
A
L
S
K
C
K
R
L
E
Q
Site 23
S294
V
K
E
Q
N
Q
T
S
A
N
N
M
R
H
L
Site 24
T302
A
N
N
M
R
H
L
T
A
E
N
N
Q
E
R
Site 25
T324
S
M
Q
Q
A
R
E
T
A
V
Q
Q
Y
K
K
Site 26
T338
K
L
E
E
E
I
Q
T
L
R
V
Y
Y
S
L
Site 27
Y342
E
I
Q
T
L
R
V
Y
Y
S
L
H
K
S
L
Site 28
Y343
I
Q
T
L
R
V
Y
Y
S
L
H
K
S
L
S
Site 29
S344
Q
T
L
R
V
Y
Y
S
L
H
K
S
L
S
Q
Site 30
S348
V
Y
Y
S
L
H
K
S
L
S
Q
E
E
N
L
Site 31
S350
Y
S
L
H
K
S
L
S
Q
E
E
N
L
K
D
Site 32
T362
L
K
D
Q
F
N
Y
T
L
S
T
Y
E
E
A
Site 33
S378
K
N
R
E
N
I
V
S
I
T
Q
Q
Q
N
E
Site 34
T396
T
Q
L
Q
Q
A
L
T
E
R
A
N
M
E
L
Site 35
S412
L
Q
H
A
R
E
A
S
Q
V
A
N
E
K
V
Site 36
T435
V
L
R
K
K
V
G
T
G
T
M
R
T
V
I
Site 37
T437
R
K
K
V
G
T
G
T
M
R
T
V
I
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation