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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF675
Full Name:
Zinc finger protein 675
Alias:
TRAF6-binding zinc finger protein;TRAF6-inhibitory zinc finger protein
Type:
Mass (Da):
66299
Number AA:
568
UniProt ID:
Q8TD23
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
R
D
V
A
I
E
F
S
L
E
E
W
Q
C
L
Site 2
Y29
D
T
A
Q
R
N
L
Y
K
N
V
I
L
E
N
Site 3
T64
E
Q
E
K
E
P
L
T
V
K
R
H
E
M
V
Site 4
S94
P
E
Q
N
I
K
D
S
F
E
K
V
T
L
R
Site 5
T99
K
D
S
F
E
K
V
T
L
R
R
Y
E
K
C
Site 6
Y103
E
K
V
T
L
R
R
Y
E
K
C
G
N
D
N
Site 7
Y149
K
M
F
Q
C
D
K
Y
V
K
V
F
N
K
F
Site 8
S157
V
K
V
F
N
K
F
S
H
S
D
R
H
K
I
Site 9
S185
G
R
S
F
C
M
L
S
H
L
T
R
H
E
R
Site 10
Y194
L
T
R
H
E
R
N
Y
T
K
V
N
F
C
K
Site 11
T195
T
R
H
E
R
N
Y
T
K
V
N
F
C
K
C
Site 12
S213
E
K
A
V
N
Q
S
S
K
L
T
K
H
K
R
Site 13
T216
V
N
Q
S
S
K
L
T
K
H
K
R
I
Y
T
Site 14
Y222
L
T
K
H
K
R
I
Y
T
C
E
K
L
Y
K
Site 15
T223
T
K
H
K
R
I
Y
T
C
E
K
L
Y
K
C
Site 16
Y228
I
Y
T
C
E
K
L
Y
K
C
Q
E
C
D
R
Site 17
Y250
L
T
E
Y
K
K
D
Y
A
R
E
K
P
Y
K
Site 18
Y256
D
Y
A
R
E
K
P
Y
K
C
E
E
C
G
K
Site 19
S268
C
G
K
A
F
N
Q
S
S
H
L
T
T
H
K
Site 20
S269
G
K
A
F
N
Q
S
S
H
L
T
T
H
K
I
Site 21
T272
F
N
Q
S
S
H
L
T
T
H
K
I
I
H
T
Site 22
T273
N
Q
S
S
H
L
T
T
H
K
I
I
H
T
G
Site 23
S297
G
K
A
F
N
Q
F
S
N
L
T
T
H
K
K
Site 24
T301
N
Q
F
S
N
L
T
T
H
K
K
I
H
T
G
Site 25
Y312
I
H
T
G
E
Q
P
Y
I
C
E
E
C
G
K
Site 26
S324
C
G
K
A
F
T
Q
S
S
T
L
T
T
H
K
Site 27
S325
G
K
A
F
T
Q
S
S
T
L
T
T
H
K
R
Site 28
T328
F
T
Q
S
S
T
L
T
T
H
K
R
I
H
T
Site 29
T329
T
Q
S
S
T
L
T
T
H
K
R
I
H
T
G
Site 30
T335
T
T
H
K
R
I
H
T
G
E
K
P
Y
K
C
Site 31
S352
C
G
K
A
F
N
R
S
S
K
L
T
E
H
K
Site 32
S353
G
K
A
F
N
R
S
S
K
L
T
E
H
K
N
Site 33
T356
F
N
R
S
S
K
L
T
E
H
K
N
I
H
T
Site 34
Y368
I
H
T
G
E
Q
P
Y
K
C
E
E
C
G
K
Site 35
S381
G
K
A
F
N
R
S
S
N
L
T
E
H
R
K
Site 36
T384
F
N
R
S
S
N
L
T
E
H
R
K
I
H
T
Site 37
Y396
I
H
T
E
E
K
P
Y
K
C
K
E
C
G
K
Site 38
S408
C
G
K
A
F
K
H
S
S
A
L
T
T
H
K
Site 39
S409
G
K
A
F
K
H
S
S
A
L
T
T
H
K
R
Site 40
T412
F
K
H
S
S
A
L
T
T
H
K
R
I
H
T
Site 41
T413
K
H
S
S
A
L
T
T
H
K
R
I
H
T
G
Site 42
S437
G
K
A
F
N
R
S
S
K
L
T
E
H
K
K
Site 43
T440
F
N
R
S
S
K
L
T
E
H
K
K
L
H
T
Site 44
S464
C
G
K
A
F
I
Q
S
S
K
L
T
E
H
K
Site 45
S465
G
K
A
F
I
Q
S
S
K
L
T
E
H
K
K
Site 46
T468
F
I
Q
S
S
K
L
T
E
H
K
K
I
H
S
Site 47
Y480
I
H
S
G
E
I
P
Y
K
C
E
E
C
G
K
Site 48
S492
C
G
K
A
F
K
H
S
S
S
L
T
T
H
K
Site 49
S493
G
K
A
F
K
H
S
S
S
L
T
T
H
K
R
Site 50
S494
K
A
F
K
H
S
S
S
L
T
T
H
K
R
I
Site 51
T496
F
K
H
S
S
S
L
T
T
H
K
R
I
H
T
Site 52
T497
K
H
S
S
S
L
T
T
H
K
R
I
H
T
G
Site 53
S518
E
E
C
G
K
A
F
S
R
S
S
K
L
T
E
Site 54
S520
C
G
K
A
F
S
R
S
S
K
L
T
E
H
K
Site 55
S521
G
K
A
F
S
R
S
S
K
L
T
E
H
K
I
Site 56
T524
F
S
R
S
S
K
L
T
E
H
K
I
I
H
T
Site 57
T552
F
N
Q
S
A
N
L
T
K
H
K
K
I
H
T
Site 58
T559
T
K
H
K
K
I
H
T
G
E
K
L
Q
N
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation