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Updated November 2019
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Protein Info
Short Name:
DNAH3
Full Name:
Dynein heavy chain 3, axonemal
Alias:
Axonemal heavy chain dynein type 3; DKFZp434N074; DLP3; Dnahc3b; Dynein heavy chain 3, axonemal: Axonemal beta dynein heavy chain 3: Ciliary dynein heavy chain 3: Dnahc3-b: Dynein heavy chain 3, axonemal: Axonemal beta dynein heavy chain 3: Ciliary dynein heavy chain 3: Dnahc3-b: Dynein heavy chain 3, axonemal: Axonemal beta dynein heavy chain 3: Ciliary dynein heavy chain 3: Dnahc3-b; Dynein, axonemal, heavy chain 3; Hsadhc3
Type:
Motor protein
Mass (Da):
470771
Number AA:
4116
UniProt ID:
Q8TD57
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005858
GO:0035085
GO:0005874
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0016887
GO:0003777
PhosphoSite+
KinaseNET
Biological Process:
GO:0001539
GO:0007018
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
A
T
G
R
L
E
L
T
L
A
A
P
P
H
P
Site 2
S24
P
G
P
A
F
Q
R
S
K
A
R
E
T
Q
G
Site 3
T29
Q
R
S
K
A
R
E
T
Q
G
E
E
E
G
S
Site 4
S36
T
Q
G
E
E
E
G
S
E
M
Q
I
A
K
S
Site 5
S43
S
E
M
Q
I
A
K
S
D
S
I
H
H
M
S
Site 6
S52
S
I
H
H
M
S
H
S
Q
G
Q
P
E
L
P
Site 7
S64
E
L
P
P
L
P
A
S
A
N
E
E
P
S
G
Site 8
Y73
N
E
E
P
S
G
L
Y
Q
T
V
M
S
H
S
Site 9
T75
E
P
S
G
L
Y
Q
T
V
M
S
H
S
F
Y
Site 10
Y82
T
V
M
S
H
S
F
Y
P
P
L
M
Q
R
T
Site 11
S90
P
P
L
M
Q
R
T
S
W
T
L
A
A
P
F
Site 12
S107
Q
H
H
H
R
G
P
S
D
S
I
A
N
N
Y
Site 13
S109
H
H
R
G
P
S
D
S
I
A
N
N
Y
S
L
Site 14
S115
D
S
I
A
N
N
Y
S
L
M
A
Q
D
L
K
Site 15
T134
L
K
V
Y
Q
P
A
T
I
S
V
P
R
D
R
Site 16
S136
V
Y
Q
P
A
T
I
S
V
P
R
D
R
T
G
Site 17
T142
I
S
V
P
R
D
R
T
G
Q
G
L
P
S
S
Site 18
S148
R
T
G
Q
G
L
P
S
S
G
N
R
S
S
S
Site 19
S149
T
G
Q
G
L
P
S
S
G
N
R
S
S
S
E
Site 20
S153
L
P
S
S
G
N
R
S
S
S
E
P
M
R
K
Site 21
S154
P
S
S
G
N
R
S
S
S
E
P
M
R
K
K
Site 22
S155
S
S
G
N
R
S
S
S
E
P
M
R
K
K
T
Site 23
T162
S
E
P
M
R
K
K
T
K
F
S
S
R
N
K
Site 24
S165
M
R
K
K
T
K
F
S
S
R
N
K
E
D
S
Site 25
S166
R
K
K
T
K
F
S
S
R
N
K
E
D
S
T
Site 26
S172
S
S
R
N
K
E
D
S
T
R
I
K
L
A
F
Site 27
T173
S
R
N
K
E
D
S
T
R
I
K
L
A
F
K
Site 28
T181
R
I
K
L
A
F
K
T
S
I
F
S
P
M
K
Site 29
S185
A
F
K
T
S
I
F
S
P
M
K
K
E
V
K
Site 30
T193
P
M
K
K
E
V
K
T
S
L
T
F
P
G
S
Site 31
S194
M
K
K
E
V
K
T
S
L
T
F
P
G
S
R
Site 32
T196
K
E
V
K
T
S
L
T
F
P
G
S
R
P
M
Site 33
S200
T
S
L
T
F
P
G
S
R
P
M
S
P
E
Q
Site 34
S204
F
P
G
S
R
P
M
S
P
E
Q
Q
L
D
V
Site 35
S227
E
S
K
E
K
K
P
S
E
S
D
L
E
R
Y
Site 36
S229
K
E
K
K
P
S
E
S
D
L
E
R
Y
Y
Y
Site 37
Y234
S
E
S
D
L
E
R
Y
Y
Y
Y
L
T
N
G
Site 38
Y235
E
S
D
L
E
R
Y
Y
Y
Y
L
T
N
G
I
Site 39
Y236
S
D
L
E
R
Y
Y
Y
Y
L
T
N
G
I
R
Site 40
Y237
D
L
E
R
Y
Y
Y
Y
L
T
N
G
I
R
K
Site 41
Y287
V
Q
E
K
E
N
D
Y
Y
C
S
L
M
K
S
Site 42
Y288
Q
E
K
E
N
D
Y
Y
C
S
L
M
K
S
I
Site 43
S313
R
K
R
L
F
I
E
S
I
P
R
L
F
P
Q
Site 44
S331
R
A
P
V
P
W
H
S
V
Y
R
S
A
K
K
Site 45
Y333
P
V
P
W
H
S
V
Y
R
S
A
K
K
W
N
Site 46
Y428
H
F
A
P
K
S
N
Y
D
S
S
R
N
I
E
Site 47
S430
A
P
K
S
N
Y
D
S
S
R
N
I
E
E
Y
Site 48
S431
P
K
S
N
Y
D
S
S
R
N
I
E
E
Y
F
Site 49
Y437
S
S
R
N
I
E
E
Y
F
A
S
V
A
S
F
Site 50
S462
K
S
L
E
D
L
V
S
L
F
M
I
H
K
D
Site 51
Y477
G
N
D
F
K
E
P
Y
Q
E
M
K
F
F
I
Site 52
Y531
N
G
I
P
K
L
K
Y
I
P
L
K
F
S
F
Site 53
T577
G
Y
N
L
L
L
G
T
V
N
A
E
E
K
L
Site 54
S586
N
A
E
E
K
L
V
S
D
F
L
I
Q
T
F
Site 55
Y606
N
Q
V
G
P
C
K
Y
L
N
V
Y
K
K
Y
Site 56
Y613
Y
L
N
V
Y
K
K
Y
V
D
L
L
D
N
T
Site 57
S654
K
R
R
N
E
I
A
S
M
N
I
T
V
P
L
Site 58
T697
Q
V
D
V
N
R
D
T
N
T
S
I
C
N
Q
Site 59
S713
S
H
I
A
D
K
V
S
E
V
P
A
N
T
K
Site 60
S724
A
N
T
K
E
L
V
S
L
I
E
F
L
K
K
Site 61
T736
L
K
K
S
S
A
V
T
V
F
K
L
R
R
Q
Site 62
S748
R
R
Q
L
R
D
A
S
E
R
L
E
F
L
M
Site 63
Y757
R
L
E
F
L
M
D
Y
A
D
L
P
Y
Q
I
Site 64
Y762
M
D
Y
A
D
L
P
Y
Q
I
E
D
I
F
D
Site 65
S771
I
E
D
I
F
D
N
S
R
N
L
L
L
H
K
Site 66
S791
M
D
L
I
K
R
C
S
E
F
E
L
R
L
E
Site 67
Y800
F
E
L
R
L
E
G
Y
H
R
E
L
E
S
F
Site 68
S806
G
Y
H
R
E
L
E
S
F
R
K
R
E
V
M
Site 69
T815
R
K
R
E
V
M
T
T
E
E
M
K
H
N
V
Site 70
S854
E
L
L
E
K
E
K
S
T
Y
P
L
L
Q
A
Site 71
Y856
L
E
K
E
K
S
T
Y
P
L
L
Q
A
M
L
Site 72
T875
P
Y
E
Q
L
W
S
T
A
Y
E
F
S
I
K
Site 73
Y877
E
Q
L
W
S
T
A
Y
E
F
S
I
K
S
E
Site 74
Y911
G
N
M
W
R
T
T
Y
K
L
I
K
T
L
S
Site 75
T916
T
T
Y
K
L
I
K
T
L
S
D
V
P
A
P
Site 76
S918
Y
K
L
I
K
T
L
S
D
V
P
A
P
R
R
Site 77
Y940
K
I
D
K
F
K
Q
Y
I
P
I
L
S
I
S
Site 78
Y966
Q
I
S
E
I
V
G
Y
E
I
K
P
T
E
T
Site 79
T971
V
G
Y
E
I
K
P
T
E
T
T
C
L
S
N
Site 80
T973
Y
E
I
K
P
T
E
T
T
C
L
S
N
M
L
Site 81
S999
E
P
I
G
A
A
A
S
K
E
Y
S
L
E
K
Site 82
S1003
A
A
A
S
K
E
Y
S
L
E
K
N
L
D
R
Site 83
Y1025
V
T
F
S
F
V
K
Y
R
D
T
D
T
N
I
Site 84
T1028
S
F
V
K
Y
R
D
T
D
T
N
I
L
C
A
Site 85
T1030
V
K
Y
R
D
T
D
T
N
I
L
C
A
I
D
Site 86
T1050
L
D
D
H
V
I
K
T
Q
T
M
C
G
S
P
Site 87
S1056
K
T
Q
T
M
C
G
S
P
F
I
K
P
I
E
Site 88
S1118
R
K
F
G
I
V
D
S
Y
W
K
S
L
M
S
Site 89
Y1119
K
F
G
I
V
D
S
Y
W
K
S
L
M
S
Q
Site 90
S1122
I
V
D
S
Y
W
K
S
L
M
S
Q
A
V
K
Site 91
S1125
S
Y
W
K
S
L
M
S
Q
A
V
K
D
N
R
Site 92
Y1163
I
Q
K
G
L
N
D
Y
L
E
K
K
R
L
F
Site 93
S1187
D
E
L
L
E
I
L
S
E
T
K
D
P
L
R
Site 94
T1227
M
I
S
S
E
K
E
T
V
P
F
I
Q
K
I
Site 95
T1306
S
Q
A
L
A
E
N
T
L
L
D
F
L
K
K
Site 96
S1314
L
L
D
F
L
K
K
S
N
D
Q
I
A
Q
I
Site 97
S1355
R
D
V
V
A
K
L
S
E
D
R
V
S
D
L
Site 98
S1360
K
L
S
E
D
R
V
S
D
L
N
D
F
Q
W
Site 99
Y1373
Q
W
I
S
Q
L
R
Y
Y
W
V
A
K
D
V
Site 100
Y1374
W
I
S
Q
L
R
Y
Y
W
V
A
K
D
V
Q
Site 101
Y1393
T
T
E
A
L
Y
G
Y
E
Y
L
G
N
S
P
Site 102
Y1395
E
A
L
Y
G
Y
E
Y
L
G
N
S
P
R
L
Site 103
S1399
G
Y
E
Y
L
G
N
S
P
R
L
V
I
T
P
Site 104
T1405
N
S
P
R
L
V
I
T
P
L
T
D
R
C
Y
Site 105
Y1412
T
P
L
T
D
R
C
Y
R
T
L
M
G
A
L
Site 106
Y1461
N
C
S
D
G
L
D
Y
K
A
M
G
K
F
F
Site 107
Y1535
F
I
T
M
N
P
G
Y
A
G
R
A
E
L
P
Site 108
Y1559
V
A
M
M
V
P
D
Y
A
L
I
G
E
I
S
Site 109
S1575
Y
S
M
G
F
L
D
S
R
S
L
A
Q
K
I
Site 110
Y1586
A
Q
K
I
V
A
T
Y
R
L
C
S
E
Q
L
Site 111
S1590
V
A
T
Y
R
L
C
S
E
Q
L
S
S
Q
H
Site 112
S1594
R
L
C
S
E
Q
L
S
S
Q
H
H
Y
D
Y
Site 113
S1595
L
C
S
E
Q
L
S
S
Q
H
H
Y
D
Y
G
Site 114
Y1599
Q
L
S
S
Q
H
H
Y
D
Y
G
M
R
A
V
Site 115
Y1601
S
S
Q
H
H
Y
D
Y
G
M
R
A
V
K
S
Site 116
Y1620
A
G
N
L
K
L
K
Y
P
E
E
N
E
S
V
Site 117
S1626
K
Y
P
E
E
N
E
S
V
L
L
L
R
A
L
Site 118
S1718
D
P
M
G
G
K
T
S
A
Y
K
V
L
A
A
Site 119
Y1743
M
E
E
F
A
V
E
Y
K
I
I
N
P
K
A
Site 120
S1782
A
F
R
E
Q
A
S
S
L
S
D
D
R
K
W
Site 121
S1784
R
E
Q
A
S
S
L
S
D
D
R
K
W
I
I
Site 122
S1841
P
A
D
L
E
Q
A
S
P
A
T
V
S
R
C
Site 123
Y1852
V
S
R
C
G
M
I
Y
M
E
P
H
Q
L
G
Site 124
S1866
G
W
K
P
L
K
D
S
Y
M
D
T
L
P
S
Site 125
Y1867
W
K
P
L
K
D
S
Y
M
D
T
L
P
S
S
Site 126
T1870
L
K
D
S
Y
M
D
T
L
P
S
S
L
T
K
Site 127
S1874
Y
M
D
T
L
P
S
S
L
T
K
E
H
K
E
Site 128
S1922
F
S
M
M
R
L
Y
S
S
L
L
D
E
I
R
Site 129
S1923
S
M
M
R
L
Y
S
S
L
L
D
E
I
R
A
Site 130
S1971
A
G
T
I
N
A
D
S
R
K
K
F
D
V
F
Site 131
S1995
D
N
H
P
R
P
K
S
V
K
L
T
K
N
N
Site 132
T1999
R
P
K
S
V
K
L
T
K
N
N
I
F
P
E
Site 133
Y2011
F
P
E
R
G
S
I
Y
D
F
Y
F
I
K
Q
Site 134
Y2014
R
G
S
I
Y
D
F
Y
F
I
K
Q
A
S
G
Site 135
Y2029
H
W
E
T
W
T
Q
Y
I
T
K
E
E
E
K
Site 136
S2057
T
M
E
T
A
R
Q
S
F
F
L
K
T
Y
L
Site 137
T2062
R
Q
S
F
F
L
K
T
Y
L
D
H
E
I
P
Site 138
Y2063
Q
S
F
F
L
K
T
Y
L
D
H
E
I
P
M
Site 139
S2081
G
P
T
G
T
G
K
S
A
I
T
N
N
F
L
Site 140
Y2096
L
H
L
P
K
N
T
Y
L
P
N
C
I
N
F
Site 141
S2104
L
P
N
C
I
N
F
S
A
R
T
S
A
N
Q
Site 142
S2108
I
N
F
S
A
R
T
S
A
N
Q
T
Q
D
I
Site 143
T2112
A
R
T
S
A
N
Q
T
Q
D
I
I
M
S
K
Site 144
T2200
G
G
G
R
N
D
I
T
G
R
F
T
R
H
L
Site 145
T2204
N
D
I
T
G
R
F
T
R
H
L
N
I
I
S
Site 146
T2265
A
V
E
N
F
L
P
T
P
S
K
S
H
Y
V
Site 147
S2267
E
N
F
L
P
T
P
S
K
S
H
Y
V
F
N
Site 148
S2269
F
L
P
T
P
S
K
S
H
Y
V
F
N
L
R
Site 149
Y2271
P
T
P
S
K
S
H
Y
V
F
N
L
R
D
F
Site 150
T2291
G
V
L
L
C
P
H
T
H
L
Q
D
V
E
K
Site 151
Y2312
H
E
V
Y
R
V
F
Y
D
R
L
I
D
K
E
Site 152
Y2366
R
S
L
F
F
G
D
Y
F
K
P
E
S
D
Q
Site 153
S2371
G
D
Y
F
K
P
E
S
D
Q
K
I
Y
D
E
Site 154
Y2376
P
E
S
D
Q
K
I
Y
D
E
I
T
D
L
K
Site 155
T2380
Q
K
I
Y
D
E
I
T
D
L
K
Q
L
T
V
Site 156
S2442
I
G
G
S
G
R
Q
S
A
A
K
L
S
T
F
Site 157
T2448
Q
S
A
A
K
L
S
T
F
M
N
A
Y
E
L
Site 158
T2532
D
I
V
E
K
M
Q
T
A
A
R
T
Q
G
E
Site 159
T2544
Q
G
E
K
V
E
V
T
P
L
S
M
Y
N
F
Site 160
Y2627
E
V
V
S
M
C
K
Y
F
Q
E
S
V
K
K
Site 161
S2631
M
C
K
Y
F
Q
E
S
V
K
K
L
S
L
D
Site 162
S2636
Q
E
S
V
K
K
L
S
L
D
Y
Y
N
K
L
Site 163
Y2639
V
K
K
L
S
L
D
Y
Y
N
K
L
R
R
H
Site 164
Y2640
K
K
L
S
L
D
Y
Y
N
K
L
R
R
H
N
Site 165
Y2648
N
K
L
R
R
H
N
Y
V
T
P
T
S
Y
L
Site 166
T2650
L
R
R
H
N
Y
V
T
P
T
S
Y
L
E
L
Site 167
T2663
E
L
I
L
T
F
K
T
L
L
N
S
K
R
Q
Site 168
S2667
T
F
K
T
L
L
N
S
K
R
Q
E
V
A
M
Site 169
Y2679
V
A
M
M
R
N
R
Y
L
T
G
L
Q
K
L
Site 170
T2681
M
M
R
N
R
Y
L
T
G
L
Q
K
L
D
F
Site 171
S2691
Q
K
L
D
F
A
A
S
Q
V
A
V
M
Q
R
Site 172
S2783
T
L
N
P
A
D
I
S
L
V
K
S
M
Q
N
Site 173
S2787
A
D
I
S
L
V
K
S
M
Q
N
P
P
G
P
Site 174
S2817
P
E
R
K
P
D
P
S
G
S
G
K
M
I
E
Site 175
Y2826
S
G
K
M
I
E
D
Y
W
G
V
S
K
K
I
Site 176
S2842
G
D
L
K
F
L
E
S
L
K
T
Y
D
K
D
Site 177
T2845
K
F
L
E
S
L
K
T
Y
D
K
D
N
I
P
Site 178
Y2846
F
L
E
S
L
K
T
Y
D
K
D
N
I
P
P
Site 179
T2855
K
D
N
I
P
P
L
T
M
K
R
I
R
E
R
Site 180
T2948
D
D
F
E
E
M
N
T
K
K
K
D
L
E
E
Site 181
T2982
G
G
E
K
D
R
W
T
E
A
A
R
Q
L
G
Site 182
T2993
R
Q
L
G
I
R
Y
T
N
L
T
G
D
V
L
Site 183
Y3016
L
G
A
F
T
V
D
Y
R
V
Q
C
Q
N
Q
Site 184
S3037
D
K
V
I
P
G
F
S
D
F
S
L
S
H
T
Site 185
S3040
I
P
G
F
S
D
F
S
L
S
H
T
L
G
D
Site 186
S3042
G
F
S
D
F
S
L
S
H
T
L
G
D
P
I
Site 187
T3044
S
D
F
S
L
S
H
T
L
G
D
P
I
K
I
Site 188
S3073
I
D
N
G
I
I
V
S
N
S
R
R
W
A
L
Site 189
S3107
K
L
A
V
I
K
F
S
D
S
N
Y
M
R
M
Site 190
Y3111
I
K
F
S
D
S
N
Y
M
R
M
L
E
N
A
Site 191
T3146
E
P
I
L
L
K
A
T
F
K
Q
Q
G
V
E
Site 192
Y3154
F
K
Q
Q
G
V
E
Y
M
R
L
G
E
N
I
Site 193
Y3164
L
G
E
N
I
I
E
Y
S
R
D
F
K
L
Y
Site 194
Y3171
Y
S
R
D
F
K
L
Y
I
T
T
R
L
R
N
Site 195
T3173
R
D
F
K
L
Y
I
T
T
R
L
R
N
P
H
Site 196
T3174
D
F
K
L
Y
I
T
T
R
L
R
N
P
H
Y
Site 197
Y3181
T
R
L
R
N
P
H
Y
L
P
E
V
A
V
K
Site 198
S3228
K
N
Q
L
I
V
E
S
A
K
N
K
K
H
L
Site 199
T3258
G
N
I
L
E
D
E
T
A
I
K
V
L
S
S
Site 200
S3264
E
T
A
I
K
V
L
S
S
S
K
V
L
S
E
Site 201
S3265
T
A
I
K
V
L
S
S
S
K
V
L
S
E
E
Site 202
S3270
L
S
S
S
K
V
L
S
E
E
I
S
E
K
Q
Site 203
S3274
K
V
L
S
E
E
I
S
E
K
Q
K
V
A
S
Site 204
T3285
K
V
A
S
M
T
E
T
Q
I
D
E
T
R
M
Site 205
Y3294
I
D
E
T
R
M
G
Y
K
P
V
A
V
H
S
Site 206
S3332
F
I
N
L
Y
M
H
S
L
T
H
S
T
K
S
Site 207
T3334
N
L
Y
M
H
S
L
T
H
S
T
K
S
E
E
Site 208
S3336
Y
M
H
S
L
T
H
S
T
K
S
E
E
L
N
Site 209
S3339
S
L
T
H
S
T
K
S
E
E
L
N
L
R
I
Site 210
Y3358
D
H
F
T
L
S
I
Y
N
N
V
C
R
S
L
Site 211
Y3407
G
I
A
L
D
N
P
Y
P
N
P
A
P
Q
W
Site 212
Y3450
L
G
E
W
K
L
I
Y
D
S
A
W
P
H
E
Site 213
S3463
H
E
E
Q
L
P
G
S
W
K
F
S
Q
G
L
Site 214
S3467
L
P
G
S
W
K
F
S
Q
G
L
E
K
M
V
Site 215
Y3500
A
E
H
M
G
K
L
Y
I
E
A
P
T
F
D
Site 216
T3505
K
L
Y
I
E
A
P
T
F
D
L
Q
G
S
Y
Site 217
S3511
P
T
F
D
L
Q
G
S
Y
N
D
S
S
C
C
Site 218
Y3512
T
F
D
L
Q
G
S
Y
N
D
S
S
C
C
A
Site 219
S3515
L
Q
G
S
Y
N
D
S
S
C
C
A
P
L
I
Site 220
T3549
L
G
M
G
G
T
R
T
Q
T
I
S
L
G
Q
Site 221
T3551
M
G
G
T
R
T
Q
T
I
S
L
G
Q
G
Q
Site 222
S3553
G
T
R
T
Q
T
I
S
L
G
Q
G
Q
G
P
Site 223
T3574
N
N
A
I
K
D
G
T
W
V
V
L
Q
N
C
Site 224
S3603
E
E
V
I
V
P
E
S
T
N
A
R
F
R
L
Site 225
T3613
A
R
F
R
L
W
L
T
S
Y
P
S
E
K
F
Site 226
S3614
R
F
R
L
W
L
T
S
Y
P
S
E
K
F
P
Site 227
Y3615
F
R
L
W
L
T
S
Y
P
S
E
K
F
P
V
Site 228
S3623
P
S
E
K
F
P
V
S
I
L
Q
N
G
I
K
Site 229
T3632
L
Q
N
G
I
K
M
T
N
E
P
P
K
G
L
Site 230
S3646
L
R
A
N
L
L
R
S
Y
L
N
D
P
I
S
Site 231
Y3647
R
A
N
L
L
R
S
Y
L
N
D
P
I
S
D
Site 232
S3653
S
Y
L
N
D
P
I
S
D
P
V
F
F
Q
S
Site 233
Y3696
P
L
G
W
N
I
P
Y
E
F
N
E
S
D
L
Site 234
S3701
I
P
Y
E
F
N
E
S
D
L
R
I
S
M
W
Site 235
Y3717
I
Q
M
F
L
N
D
Y
K
E
V
P
F
D
A
Site 236
T3726
E
V
P
F
D
A
L
T
Y
L
T
G
E
C
N
Site 237
T3739
C
N
Y
G
G
R
V
T
D
D
K
D
R
R
L
Site 238
Y3763
C
K
E
I
E
E
D
Y
Y
S
L
A
P
G
D
Site 239
Y3764
K
E
I
E
E
D
Y
Y
S
L
A
P
G
D
T
Site 240
S3765
E
I
E
E
D
Y
Y
S
L
A
P
G
D
T
Y
Site 241
T3771
Y
S
L
A
P
G
D
T
Y
Y
I
P
P
H
G
Site 242
Y3772
S
L
A
P
G
D
T
Y
Y
I
P
P
H
G
S
Site 243
Y3773
L
A
P
G
D
T
Y
Y
I
P
P
H
G
S
Y
Site 244
Y3780
Y
I
P
P
H
G
S
Y
Q
S
Y
I
D
Y
L
Site 245
S3782
P
P
H
G
S
Y
Q
S
Y
I
D
Y
L
R
N
Site 246
Y3783
P
H
G
S
Y
Q
S
Y
I
D
Y
L
R
N
L
Site 247
Y3786
S
Y
Q
S
Y
I
D
Y
L
R
N
L
P
I
T
Site 248
T3808
L
H
E
N
A
D
I
T
K
D
N
Q
E
T
N
Site 249
S3829
L
L
T
L
P
R
Q
S
G
G
S
G
K
S
P
Site 250
S3832
L
P
R
Q
S
G
G
S
G
K
S
P
Q
E
V
Site 251
S3835
Q
S
G
G
S
G
K
S
P
Q
E
V
V
E
E
Site 252
S3849
E
L
A
Q
D
I
L
S
K
L
P
R
D
F
D
Site 253
Y3864
L
E
E
V
M
K
L
Y
P
V
V
Y
E
E
S
Site 254
Y3868
M
K
L
Y
P
V
V
Y
E
E
S
M
N
T
V
Site 255
T3874
V
Y
E
E
S
M
N
T
V
L
R
Q
E
L
I
Site 256
T3887
L
I
R
F
N
R
L
T
K
V
V
R
R
S
L
Site 257
S3909
K
G
Q
V
L
M
S
S
E
L
E
E
V
F
N
Site 258
S3931
P
A
M
W
A
A
K
S
Y
P
S
L
K
P
L
Site 259
Y3932
A
M
W
A
A
K
S
Y
P
S
L
K
P
L
G
Site 260
S3934
W
A
A
K
S
Y
P
S
L
K
P
L
G
G
Y
Site 261
Y3941
S
L
K
P
L
G
G
Y
V
A
D
L
L
A
R
Site 262
S3980
Q
S
F
L
T
G
V
S
Q
N
Y
A
R
K
Y
Site 263
Y3983
L
T
G
V
S
Q
N
Y
A
R
K
Y
T
I
P
Site 264
Y3987
S
Q
N
Y
A
R
K
Y
T
I
P
I
D
H
I
Site 265
T3988
Q
N
Y
A
R
K
Y
T
I
P
I
D
H
I
G
Site 266
T4001
I
G
F
E
F
E
V
T
P
Q
E
T
V
M
E
Site 267
Y4016
N
N
P
E
D
G
A
Y
I
K
G
L
F
L
E
Site 268
T4031
G
A
R
W
D
R
K
T
M
Q
I
G
E
S
L
Site 269
S4037
K
T
M
Q
I
G
E
S
L
P
K
I
L
Y
D
Site 270
Y4070
D
I
Y
V
C
P
V
Y
K
T
S
A
R
R
G
Site 271
T4072
Y
V
C
P
V
Y
K
T
S
A
R
R
G
T
L
Site 272
S4073
V
C
P
V
Y
K
T
S
A
R
R
G
T
L
S
Site 273
T4078
K
T
S
A
R
R
G
T
L
S
T
T
G
H
S
Site 274
S4080
S
A
R
R
G
T
L
S
T
T
G
H
S
T
N
Site 275
T4081
A
R
R
G
T
L
S
T
T
G
H
S
T
N
Y
Site 276
Y4088
T
T
G
H
S
T
N
Y
V
L
S
I
E
L
P
Site 277
S4091
H
S
T
N
Y
V
L
S
I
E
L
P
T
D
M
Site 278
T4096
V
L
S
I
E
L
P
T
D
M
P
Q
K
H
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation