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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DSCAML1
Full Name:
Down syndrome cell adhesion molecule-like protein 1
Alias:
Down syndrome cell adhesion molecule 2; Down syndrome cell adhesion molecule like 1; DSCAM2; DSCL1; KIAA1132
Type:
Adhesion
Mass (Da):
224460
Number AA:
UniProt ID:
Q8TD84
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0009986
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0042803
PhosphoSite+
KinaseNET
Biological Process:
GO:0007409
GO:0007420
GO:0001709
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y531
I
N
C
R
V
I
G
Y
P
Y
Y
S
I
K
W
Site 2
Y533
C
R
V
I
G
Y
P
Y
Y
S
I
K
W
Y
K
Site 3
Y534
R
V
I
G
Y
P
Y
Y
S
I
K
W
Y
K
D
Site 4
S1629
K
R
L
R
D
A
K
S
L
A
E
M
L
I
S
Site 5
S1636
S
L
A
E
M
L
I
S
K
N
N
R
S
F
D
Site 6
S1641
L
I
S
K
N
N
R
S
F
D
T
P
V
K
G
Site 7
T1644
K
N
N
R
S
F
D
T
P
V
K
G
P
P
Q
Site 8
T1685
D
K
A
T
I
P
V
T
D
A
E
F
S
Q
A
Site 9
S1690
P
V
T
D
A
E
F
S
Q
A
V
N
P
Q
S
Site 10
T1708
G
V
S
L
H
H
P
T
L
I
Q
S
T
G
P
Site 11
S1720
T
G
P
L
I
D
M
S
D
I
R
P
G
T
N
Site 12
T1726
M
S
D
I
R
P
G
T
N
P
V
S
R
K
N
Site 13
S1730
R
P
G
T
N
P
V
S
R
K
N
V
K
S
A
Site 14
S1736
V
S
R
K
N
V
K
S
A
H
S
T
R
N
R
Site 15
S1739
K
N
V
K
S
A
H
S
T
R
N
R
Y
S
S
Site 16
T1740
N
V
K
S
A
H
S
T
R
N
R
Y
S
S
Q
Site 17
Y1744
A
H
S
T
R
N
R
Y
S
S
Q
W
T
L
T
Site 18
S1745
H
S
T
R
N
R
Y
S
S
Q
W
T
L
T
K
Site 19
S1746
S
T
R
N
R
Y
S
S
Q
W
T
L
T
K
C
Site 20
T1749
N
R
Y
S
S
Q
W
T
L
T
K
C
Q
A
S
Site 21
T1751
Y
S
S
Q
W
T
L
T
K
C
Q
A
S
T
P
Site 22
T1757
L
T
K
C
Q
A
S
T
P
A
R
T
L
T
S
Site 23
T1763
S
T
P
A
R
T
L
T
S
D
W
R
T
V
G
Site 24
T1768
T
L
T
S
D
W
R
T
V
G
S
Q
H
G
V
Site 25
S1771
S
D
W
R
T
V
G
S
Q
H
G
V
T
V
T
Site 26
T1776
V
G
S
Q
H
G
V
T
V
T
E
S
D
S
Y
Site 27
T1778
S
Q
H
G
V
T
V
T
E
S
D
S
Y
S
A
Site 28
S1780
H
G
V
T
V
T
E
S
D
S
Y
S
A
S
L
Site 29
S1782
V
T
V
T
E
S
D
S
Y
S
A
S
L
S
Q
Site 30
Y1783
T
V
T
E
S
D
S
Y
S
A
S
L
S
Q
D
Site 31
S1784
V
T
E
S
D
S
Y
S
A
S
L
S
Q
D
T
Site 32
S1786
E
S
D
S
Y
S
A
S
L
S
Q
D
T
D
K
Site 33
S1788
D
S
Y
S
A
S
L
S
Q
D
T
D
K
G
R
Site 34
T1791
S
A
S
L
S
Q
D
T
D
K
G
R
N
S
M
Site 35
S1797
D
T
D
K
G
R
N
S
M
V
S
T
E
S
A
Site 36
S1800
K
G
R
N
S
M
V
S
T
E
S
A
S
S
T
Site 37
T1801
G
R
N
S
M
V
S
T
E
S
A
S
S
T
Y
Site 38
S1803
N
S
M
V
S
T
E
S
A
S
S
T
Y
E
E
Site 39
S1806
V
S
T
E
S
A
S
S
T
Y
E
E
L
A
R
Site 40
T1807
S
T
E
S
A
S
S
T
Y
E
E
L
A
R
A
Site 41
Y1815
Y
E
E
L
A
R
A
Y
E
H
A
K
L
E
E
Site 42
T1832
Q
H
A
K
F
E
I
T
E
C
F
I
S
D
S
Site 43
S1837
E
I
T
E
C
F
I
S
D
S
S
S
D
Q
M
Site 44
S1839
T
E
C
F
I
S
D
S
S
S
D
Q
M
T
T
Site 45
S1841
C
F
I
S
D
S
S
S
D
Q
M
T
T
G
T
Site 46
T1845
D
S
S
S
D
Q
M
T
T
G
T
N
E
N
A
Site 47
S1854
G
T
N
E
N
A
D
S
M
T
S
M
S
T
P
Site 48
T1856
N
E
N
A
D
S
M
T
S
M
S
T
P
S
E
Site 49
S1857
E
N
A
D
S
M
T
S
M
S
T
P
S
E
P
Site 50
S1859
A
D
S
M
T
S
M
S
T
P
S
E
P
G
I
Site 51
T1860
D
S
M
T
S
M
S
T
P
S
E
P
G
I
C
Site 52
S1862
M
T
S
M
S
T
P
S
E
P
G
I
C
R
F
Site 53
T1870
E
P
G
I
C
R
F
T
A
S
P
P
K
P
Q
Site 54
S1872
G
I
C
R
F
T
A
S
P
P
K
P
Q
D
A
Site 55
S1896
I
P
H
R
A
N
K
S
D
Y
C
N
L
P
L
Site 56
Y1898
H
R
A
N
K
S
D
Y
C
N
L
P
L
Y
A
Site 57
Y1904
D
Y
C
N
L
P
L
Y
A
K
S
E
A
F
F
Site 58
S1907
N
L
P
L
Y
A
K
S
E
A
F
F
R
K
A
Site 59
S1929
V
V
P
P
R
E
A
S
I
R
N
L
A
R
T
Site 60
T1936
S
I
R
N
L
A
R
T
Y
H
T
Q
A
R
H
Site 61
Y1937
I
R
N
L
A
R
T
Y
H
T
Q
A
R
H
L
Site 62
T1945
H
T
Q
A
R
H
L
T
L
D
P
A
S
K
S
Site 63
S1950
H
L
T
L
D
P
A
S
K
S
L
G
L
P
H
Site 64
S1952
T
L
D
P
A
S
K
S
L
G
L
P
H
P
G
Site 65
S1965
P
G
A
P
A
A
A
S
T
A
T
L
P
Q
R
Site 66
T1983
M
P
A
P
P
A
G
T
A
P
P
A
P
G
P
Site 67
T1991
A
P
P
A
P
G
P
T
P
A
E
P
P
T
A
Site 68
T1997
P
T
P
A
E
P
P
T
A
P
S
A
A
P
P
Site 69
S2000
A
E
P
P
T
A
P
S
A
A
P
P
A
P
S
Site 70
S2007
S
A
A
P
P
A
P
S
T
E
P
P
R
A
G
Site 71
T2008
A
A
P
P
A
P
S
T
E
P
P
R
A
G
G
Site 72
T2018
P
R
A
G
G
P
H
T
K
M
G
G
S
R
D
Site 73
S2023
P
H
T
K
M
G
G
S
R
D
S
L
L
E
M
Site 74
S2026
K
M
G
G
S
R
D
S
L
L
E
M
S
T
S
Site 75
S2031
R
D
S
L
L
E
M
S
T
S
G
V
G
R
S
Site 76
S2033
S
L
L
E
M
S
T
S
G
V
G
R
S
Q
K
Site 77
S2038
S
T
S
G
V
G
R
S
Q
K
Q
G
A
G
A
Site 78
S2047
K
Q
G
A
G
A
Y
S
K
S
Y
T
L
V
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation