PhosphoNET

           
Protein Info 
   
Short Name:  NETO1
Full Name:  Neuropilin and tolloid-like protein 1
Alias:  BCTL1; Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains 1; BTCL1; Neuropilin (NRP) and tolloid (TLL)-like 1; Neuropilin and tolloid-like 1
Type:  Extracellular region, Plasma membrane, Integral membrane protein
Mass (Da):  60218
Number AA:  533
UniProt ID:  Q8TDF5
International Prot ID:  IPI00171400
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005576  GO:0016021  GO:0005886 Uniprot OncoNet
Molecular Function:  GO:0004872     PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y372IKQPRKKYVQRKSDF
Site 2S377KKYVQRKSDFDQTVF
Site 3T382RKSDFDQTVFQEVFE
Site 4Y393EVFEPPHYELCTLRG
Site 5T397PPHYELCTLRGTGAT
Site 6Y417VADDFENYHKLRRSS
Site 7S423NYHKLRRSSSKCIHD
Site 8S424YHKLRRSSSKCIHDH
Site 9S425HKLRRSSSKCIHDHH
Site 10S435IHDHHCGSQLSSTKG
Site 11S438HHCGSQLSSTKGSRS
Site 12S439HCGSQLSSTKGSRSN
Site 13T440CGSQLSSTKGSRSNL
Site 14S443QLSSTKGSRSNLSTR
Site 15S445SSTKGSRSNLSTRDA
Site 16S448KGSRSNLSTRDASIL
Site 17T449GSRSNLSTRDASILT
Site 18S453NLSTRDASILTEMPT
Site 19T456TRDASILTEMPTQPG
Site 20T460SILTEMPTQPGKPLI
Site 21T500DEIEEVPTTSHRLSR
Site 22T501EIEEVPTTSHRLSRH
Site 23S502IEEVPTTSHRLSRHD
Site 24S506PTTSHRLSRHDKAVQ
Site 25S520QRFCLIGSLSKHESE
Site 26S522FCLIGSLSKHESEYN
Site 27S526GSLSKHESEYNTTRV
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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