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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BXDC2
Full Name:
Ribosome biogenesis protein BRX1 homolog
Alias:
BRIX; Brix domain containing 2; Brix domain containing protein 2; BRX1, biogenesis of ribosomes,; FLJ11100; Ribosome biogenesis protein Brix
Type:
Unknown function
Mass (Da):
41401
Number AA:
353
UniProt ID:
Q8TDN6
International Prot ID:
IPI00181728
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0042254
GO:0009987
GO:0016043
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T35
P
P
A
K
R
H
A
T
A
E
E
V
E
E
E
Site 2
S66
K
E
R
I
L
I
F
S
S
R
G
I
N
F
R
Site 3
S88
L
R
M
L
M
P
H
S
K
A
D
T
K
M
D
Site 4
T92
M
P
H
S
K
A
D
T
K
M
D
R
K
D
K
Site 5
Y117
K
N
C
N
K
C
I
Y
F
E
A
K
K
K
Q
Site 6
Y127
A
K
K
K
Q
D
L
Y
M
W
L
S
N
S
P
Site 7
S131
Q
D
L
Y
M
W
L
S
N
S
P
H
G
P
S
Site 8
S133
L
Y
M
W
L
S
N
S
P
H
G
P
S
A
K
Site 9
T155
T
L
A
E
L
K
M
T
G
N
C
L
K
G
S
Site 10
S162
T
G
N
C
L
K
G
S
R
P
L
L
S
F
D
Site 11
S167
K
G
S
R
P
L
L
S
F
D
P
A
F
D
E
Site 12
Y178
A
F
D
E
L
P
H
Y
A
L
L
K
E
L
L
Site 13
S190
E
L
L
I
Q
I
F
S
T
P
R
Y
H
P
K
Site 14
T191
L
L
I
Q
I
F
S
T
P
R
Y
H
P
K
S
Site 15
Y194
Q
I
F
S
T
P
R
Y
H
P
K
S
Q
P
F
Site 16
S198
T
P
R
Y
H
P
K
S
Q
P
F
V
D
H
V
Site 17
T252
Q
G
S
F
G
G
P
T
L
Y
E
N
P
H
Y
Site 18
Y254
S
F
G
G
P
T
L
Y
E
N
P
H
Y
Q
S
Site 19
Y259
T
L
Y
E
N
P
H
Y
Q
S
P
N
M
H
R
Site 20
S261
Y
E
N
P
H
Y
Q
S
P
N
M
H
R
R
V
Site 21
S271
M
H
R
R
V
I
R
S
I
T
A
A
K
Y
R
Site 22
T273
R
R
V
I
R
S
I
T
A
A
K
Y
R
E
K
Site 23
Y277
R
S
I
T
A
A
K
Y
R
E
K
Q
Q
V
K
Site 24
T296
L
R
K
K
E
P
K
T
L
L
P
H
D
P
T
Site 25
T309
P
T
A
D
V
F
V
T
P
A
E
E
K
P
I
Site 26
Y337
K
A
R
K
K
R
I
Y
K
R
Q
R
K
M
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation