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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PANK1
Full Name:
Pantothenate kinase 1
Alias:
Pantothenic acid kinase 1
Type:
Mass (Da):
64321
Number AA:
598
UniProt ID:
Q8TE04
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004594
PhosphoSite+
KinaseNET
Biological Process:
GO:0015937
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S44
Q
G
K
A
G
G
G
S
P
G
W
G
C
A
G
Site 2
S82
G
A
E
E
V
G
E
S
A
G
G
G
E
E
R
Site 3
T115
G
G
S
G
E
I
K
T
P
E
N
D
L
Q
R
Site 4
S126
D
L
Q
R
G
R
L
S
R
G
P
R
T
A
P
Site 5
T131
R
L
S
R
G
P
R
T
A
P
P
A
P
G
M
Site 6
S148
R
S
G
Q
Q
E
R
S
V
P
H
S
P
G
A
Site 7
S152
Q
E
R
S
V
P
H
S
P
G
A
P
V
G
T
Site 8
S184
V
Q
P
P
H
V
C
S
R
G
P
V
G
G
S
Site 9
S215
P
L
L
P
Q
H
D
S
P
A
K
K
C
R
L
Site 10
S228
R
L
R
R
R
M
D
S
G
R
K
N
R
P
P
Site 11
S272
E
E
V
E
N
L
K
S
I
R
K
Y
L
T
S
Site 12
Y276
N
L
K
S
I
R
K
Y
L
T
S
N
T
A
Y
Site 13
T278
K
S
I
R
K
Y
L
T
S
N
T
A
Y
G
K
Site 14
S279
S
I
R
K
Y
L
T
S
N
T
A
Y
G
K
T
Site 15
Y283
Y
L
T
S
N
T
A
Y
G
K
T
G
I
R
D
Site 16
T286
S
N
T
A
Y
G
K
T
G
I
R
D
V
H
L
Site 17
S325
H
R
F
I
Q
M
G
S
E
K
N
F
S
S
L
Site 18
S330
M
G
S
E
K
N
F
S
S
L
H
T
T
L
C
Site 19
S331
G
S
E
K
N
F
S
S
L
H
T
T
L
C
A
Site 20
T334
K
N
F
S
S
L
H
T
T
L
C
A
T
G
G
Site 21
S376
Q
G
L
L
Y
V
D
S
V
G
F
N
G
K
P
Site 22
Y387
N
G
K
P
E
C
Y
Y
F
E
N
P
T
N
P
Site 23
Y402
E
L
C
Q
K
K
P
Y
C
L
D
N
P
Y
P
Site 24
Y430
A
V
Y
S
K
D
N
Y
K
R
V
T
G
T
S
Site 25
T434
K
D
N
Y
K
R
V
T
G
T
S
L
G
G
G
Site 26
S437
Y
K
R
V
T
G
T
S
L
G
G
G
T
F
L
Site 27
T469
M
A
A
K
G
D
S
T
N
V
D
K
L
V
K
Site 28
Y479
D
K
L
V
K
D
I
Y
G
G
D
Y
E
R
F
Site 29
Y483
K
D
I
Y
G
G
D
Y
E
R
F
G
L
Q
G
Site 30
S491
E
R
F
G
L
Q
G
S
A
V
A
S
S
F
G
Site 31
S496
Q
G
S
A
V
A
S
S
F
G
N
M
M
S
K
Site 32
S502
S
S
F
G
N
M
M
S
K
E
K
R
D
S
I
Site 33
S508
M
S
K
E
K
R
D
S
I
S
K
E
D
L
A
Site 34
S510
K
E
K
R
D
S
I
S
K
E
D
L
A
R
A
Site 35
T518
K
E
D
L
A
R
A
T
L
V
T
I
T
N
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation