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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MORC4
Full Name:
MORC family CW-type zinc finger protein 4
Alias:
ZCWCC2; Zinc finger CW-type coiled-coil domain protein 2
Type:
Mass (Da):
106348
Number AA:
937
UniProt ID:
Q8TE76
International Prot ID:
IPI00163550
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S33
Q
A
F
G
I
R
L
S
T
M
S
P
R
Y
L
Site 2
T34
A
F
G
I
R
L
S
T
M
S
P
R
Y
L
Q
Site 3
S36
G
I
R
L
S
T
M
S
P
R
Y
L
Q
S
N
Site 4
Y39
L
S
T
M
S
P
R
Y
L
Q
S
N
S
S
S
Site 5
S42
M
S
P
R
Y
L
Q
S
N
S
S
S
H
T
R
Site 6
S44
P
R
Y
L
Q
S
N
S
S
S
H
T
R
P
F
Site 7
S45
R
Y
L
Q
S
N
S
S
S
H
T
R
P
F
S
Site 8
S46
Y
L
Q
S
N
S
S
S
H
T
R
P
F
S
A
Site 9
T48
Q
S
N
S
S
S
H
T
R
P
F
S
A
I
A
Site 10
S52
S
S
H
T
R
P
F
S
A
I
A
E
L
L
D
Site 11
S82
V
E
E
V
K
N
K
S
C
L
T
F
T
D
D
Site 12
T85
V
K
N
K
S
C
L
T
F
T
D
D
G
C
G
Site 13
T87
N
K
S
C
L
T
F
T
D
D
G
C
G
M
T
Site 14
T94
T
D
D
G
C
G
M
T
P
H
K
L
H
R
M
Site 15
S103
H
K
L
H
R
M
L
S
F
G
F
T
D
K
V
Site 16
T107
R
M
L
S
F
G
F
T
D
K
V
I
K
K
S
Site 17
S114
T
D
K
V
I
K
K
S
Q
C
P
I
G
V
F
Site 18
S127
V
F
G
N
G
F
K
S
G
S
M
R
L
G
K
Site 19
S129
G
N
G
F
K
S
G
S
M
R
L
G
K
D
A
Site 20
T147
T
K
N
G
G
T
L
T
V
G
L
L
S
Q
T
Site 21
S231
R
R
N
K
N
G
K
S
E
L
D
F
D
T
D
Site 22
T237
K
S
E
L
D
F
D
T
D
Q
Y
D
I
L
V
Site 23
Y240
L
D
F
D
T
D
Q
Y
D
I
L
V
S
D
F
Site 24
S245
D
Q
Y
D
I
L
V
S
D
F
D
T
E
E
K
Site 25
T249
I
L
V
S
D
F
D
T
E
E
K
M
T
G
G
Site 26
T254
F
D
T
E
E
K
M
T
G
G
V
T
S
E
L
Site 27
S259
K
M
T
G
G
V
T
S
E
L
P
E
T
E
Y
Site 28
T264
V
T
S
E
L
P
E
T
E
Y
S
L
R
A
F
Site 29
Y266
S
E
L
P
E
T
E
Y
S
L
R
A
F
C
G
Site 30
S267
E
L
P
E
T
E
Y
S
L
R
A
F
C
G
I
Site 31
S298
T
T
Q
M
I
A
K
S
L
A
N
V
E
Y
D
Site 32
Y304
K
S
L
A
N
V
E
Y
D
T
Y
K
P
T
F
Site 33
T306
L
A
N
V
E
Y
D
T
Y
K
P
T
F
T
N
Site 34
Y307
A
N
V
E
Y
D
T
Y
K
P
T
F
T
N
K
Site 35
T310
E
Y
D
T
Y
K
P
T
F
T
N
K
Q
V
R
Site 36
T319
T
N
K
Q
V
R
I
T
F
G
F
S
C
K
N
Site 37
Y381
Y
N
K
Q
D
F
E
Y
T
K
E
Y
R
L
T
Site 38
T388
Y
T
K
E
Y
R
L
T
I
N
A
L
A
Q
K
Site 39
S405
A
Y
W
K
E
K
T
S
Q
D
N
F
E
T
S
Site 40
S412
S
Q
D
N
F
E
T
S
T
V
A
R
P
I
P
Site 41
T413
Q
D
N
F
E
T
S
T
V
A
R
P
I
P
K
Site 42
S445
L
P
G
K
I
D
P
S
M
L
P
A
R
W
F
Site 43
Y461
Y
Y
N
S
H
P
K
Y
R
R
C
S
V
P
E
Site 44
S465
H
P
K
Y
R
R
C
S
V
P
E
E
Q
E
L
Site 45
T473
V
P
E
E
Q
E
L
T
D
E
D
L
C
L
S
Site 46
S480
T
D
E
D
L
C
L
S
K
A
K
K
Q
E
Q
Site 47
T513
S
N
P
P
K
I
L
T
V
Q
E
M
A
G
L
Site 48
S532
I
G
Y
E
G
I
H
S
P
S
V
L
P
S
G
Site 49
S534
Y
E
G
I
H
S
P
S
V
L
P
S
G
G
E
Site 50
S538
H
S
P
S
V
L
P
S
G
G
E
E
S
R
S
Site 51
S543
L
P
S
G
G
E
E
S
R
S
P
S
L
Q
L
Site 52
S545
S
G
G
E
E
S
R
S
P
S
L
Q
L
K
P
Site 53
S547
G
E
E
S
R
S
P
S
L
Q
L
K
P
L
D
Site 54
S555
L
Q
L
K
P
L
D
S
S
V
L
Q
F
S
S
Site 55
S556
Q
L
K
P
L
D
S
S
V
L
Q
F
S
S
K
Site 56
S562
S
S
V
L
Q
F
S
S
K
Y
K
W
I
L
G
Site 57
Y564
V
L
Q
F
S
S
K
Y
K
W
I
L
G
E
E
Site 58
T584
R
R
L
Q
N
E
M
T
T
P
S
L
D
Y
S
Site 59
T585
R
L
Q
N
E
M
T
T
P
S
L
D
Y
S
M
Site 60
S587
Q
N
E
M
T
T
P
S
L
D
Y
S
M
P
A
Site 61
Y590
M
T
T
P
S
L
D
Y
S
M
P
A
P
Y
R
Site 62
S591
T
T
P
S
L
D
Y
S
M
P
A
P
Y
R
R
Site 63
Y596
D
Y
S
M
P
A
P
Y
R
R
V
E
A
P
V
Site 64
Y605
R
V
E
A
P
V
A
Y
P
E
G
E
N
S
H
Site 65
S611
A
Y
P
E
G
E
N
S
H
D
K
S
S
S
E
Site 66
S615
G
E
N
S
H
D
K
S
S
S
E
R
S
T
P
Site 67
S616
E
N
S
H
D
K
S
S
S
E
R
S
T
P
P
Site 68
S617
N
S
H
D
K
S
S
S
E
R
S
T
P
P
Y
Site 69
S620
D
K
S
S
S
E
R
S
T
P
P
Y
L
F
P
Site 70
T621
K
S
S
S
E
R
S
T
P
P
Y
L
F
P
E
Site 71
Y624
S
E
R
S
T
P
P
Y
L
F
P
E
Y
P
E
Site 72
Y629
P
P
Y
L
F
P
E
Y
P
E
A
S
K
N
T
Site 73
S643
T
G
Q
N
R
E
V
S
I
L
Y
P
G
A
K
Site 74
Y646
N
R
E
V
S
I
L
Y
P
G
A
K
D
Q
R
Site 75
S656
A
K
D
Q
R
Q
G
S
L
L
P
E
E
L
E
Site 76
S674
P
R
L
V
A
E
E
S
N
R
G
S
T
T
I
Site 77
S678
A
E
E
S
N
R
G
S
T
T
I
N
K
E
E
Site 78
T679
E
E
S
N
R
G
S
T
T
I
N
K
E
E
V
Site 79
S704
V
A
K
G
V
R
D
S
G
A
P
I
Q
L
I
Site 80
S727
E
R
R
K
A
V
E
S
W
N
P
V
P
Y
S
Site 81
Y752
I
G
E
K
A
R
G
Y
E
E
S
E
G
H
N
Site 82
S755
K
A
R
G
Y
E
E
S
E
G
H
N
T
P
K
Site 83
T760
E
E
S
E
G
H
N
T
P
K
L
K
N
Q
R
Site 84
T775
E
L
E
E
L
K
R
T
T
E
K
L
E
R
V
Site 85
T776
L
E
E
L
K
R
T
T
E
K
L
E
R
V
L
Site 86
Y817
V
Q
H
E
L
V
I
Y
S
T
Q
E
A
E
G
Site 87
T819
H
E
L
V
I
Y
S
T
Q
E
A
E
G
L
Y
Site 88
Y826
T
Q
E
A
E
G
L
Y
W
S
K
K
H
M
G
Site 89
T849
L
K
A
E
L
E
R
T
K
E
E
K
Q
E
L
Site 90
Y877
L
Q
K
A
Q
V
S
Y
R
T
P
E
G
D
D
Site 91
T879
K
A
Q
V
S
Y
R
T
P
E
G
D
D
L
E
Site 92
Y917
L
E
L
R
E
I
G
Y
D
S
E
Q
V
D
G
Site 93
Y927
E
Q
V
D
G
I
L
Y
T
V
L
E
A
N
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation