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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SSH3
Full Name:
Protein phosphatase Slingshot homolog 3
Alias:
EC 3.1.3.16; EC 3.1.3.48; FLJ10928; FLJ20515; HSSH-3L; Slingshot 3; SSH-3; SSH3L; SSH-3L
Type:
EC 3.1.3.16; Cytoskeletal protein; EC 3.1.3.48; Phosphatase
Mass (Da):
72996
Number AA:
659
UniProt ID:
Q8TE77
International Prot ID:
IPI00218486
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0004725
GO:0008138
PhosphoSite+
KinaseNET
Biological Process:
GO:0006470
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
L
V
T
V
S
R
S
P
P
G
S
G
Site 2
S9
A
L
V
T
V
S
R
S
P
P
G
S
G
A
S
Site 3
S13
V
S
R
S
P
P
G
S
G
A
S
T
P
V
G
Site 4
S16
S
P
P
G
S
G
A
S
T
P
V
G
P
W
D
Site 5
T17
P
P
G
S
G
A
S
T
P
V
G
P
W
D
Q
Site 6
S30
D
Q
A
V
Q
R
R
S
R
L
Q
R
R
Q
S
Site 7
S37
S
R
L
Q
R
R
Q
S
F
A
V
L
R
G
A
Site 8
S61
N
D
D
A
A
E
A
S
S
E
P
T
E
K
A
Site 9
S70
E
P
T
E
K
A
P
S
E
E
E
L
H
G
D
Site 10
T79
E
E
L
H
G
D
Q
T
D
F
G
Q
G
S
Q
Site 11
S85
Q
T
D
F
G
Q
G
S
Q
S
P
Q
K
Q
E
Site 12
S87
D
F
G
Q
G
S
Q
S
P
Q
K
Q
E
E
Q
Site 13
Y127
P
R
P
P
R
L
R
Y
L
L
V
V
S
T
R
Site 14
S140
T
R
E
G
E
G
L
S
Q
D
E
T
V
L
L
Site 15
S154
L
G
V
D
F
P
D
S
S
S
P
S
C
T
L
Site 16
S155
G
V
D
F
P
D
S
S
S
P
S
C
T
L
G
Site 17
S156
V
D
F
P
D
S
S
S
P
S
C
T
L
G
L
Site 18
T171
V
L
P
L
W
S
D
T
Q
V
Y
L
D
G
D
Site 19
Y174
L
W
S
D
T
Q
V
Y
L
D
G
D
G
G
F
Site 20
S182
L
D
G
D
G
G
F
S
V
T
S
G
G
Q
S
Site 21
S185
D
G
G
F
S
V
T
S
G
G
Q
S
R
I
F
Site 22
S189
S
V
T
S
G
G
Q
S
R
I
F
K
P
I
S
Site 23
Y232
A
L
T
W
A
S
H
Y
Q
E
R
L
N
S
E
Site 24
S238
H
Y
Q
E
R
L
N
S
E
Q
S
C
L
N
E
Site 25
S241
E
R
L
N
S
E
Q
S
C
L
N
E
W
T
A
Site 26
S254
T
A
M
A
D
L
E
S
L
R
P
P
S
A
E
Site 27
S259
L
E
S
L
R
P
P
S
A
E
P
G
G
S
S
Site 28
S265
P
S
A
E
P
G
G
S
S
E
Q
E
Q
M
E
Site 29
S266
S
A
E
P
G
G
S
S
E
Q
E
Q
M
E
Q
Site 30
S290
L
D
V
S
D
L
E
S
V
T
S
K
E
I
R
Site 31
T292
V
S
D
L
E
S
V
T
S
K
E
I
R
Q
A
Site 32
S293
S
D
L
E
S
V
T
S
K
E
I
R
Q
A
L
Site 33
Y311
L
G
L
P
L
Q
Q
Y
R
D
F
I
D
N
Q
Site 34
S330
V
A
Q
R
D
R
A
S
R
I
F
P
H
L
Y
Site 35
Y337
S
R
I
F
P
H
L
Y
L
G
S
E
W
N
A
Site 36
T356
E
L
Q
R
N
R
V
T
H
I
L
N
M
A
R
Site 37
Y369
A
R
E
I
D
N
F
Y
P
E
R
F
T
Y
H
Site 38
Y375
F
Y
P
E
R
F
T
Y
H
N
V
R
L
W
D
Site 39
S385
V
R
L
W
D
E
E
S
A
Q
L
L
P
H
W
Site 40
T395
L
L
P
H
W
K
E
T
H
R
F
I
E
A
A
Site 41
S435
A
M
K
Q
Y
E
C
S
L
E
Q
A
L
R
H
Site 42
T468
Q
I
Y
Q
G
I
L
T
A
S
R
Q
S
H
V
Site 43
S473
I
L
T
A
S
R
Q
S
H
V
W
E
Q
K
V
Site 44
S484
E
Q
K
V
G
G
V
S
P
E
E
H
P
A
P
Site 45
S494
E
H
P
A
P
E
V
S
T
P
F
P
P
L
P
Site 46
T495
H
P
A
P
E
V
S
T
P
F
P
P
L
P
P
Site 47
S540
N
L
R
G
V
M
R
S
I
S
L
L
E
P
S
Site 48
S542
R
G
V
M
R
S
I
S
L
L
E
P
S
L
E
Site 49
S547
S
I
S
L
L
E
P
S
L
E
L
E
S
T
S
Site 50
S552
E
P
S
L
E
L
E
S
T
S
E
T
S
D
M
Site 51
T553
P
S
L
E
L
E
S
T
S
E
T
S
D
M
P
Site 52
S554
S
L
E
L
E
S
T
S
E
T
S
D
M
P
E
Site 53
S557
L
E
S
T
S
E
T
S
D
M
P
E
V
F
S
Site 54
S564
S
D
M
P
E
V
F
S
S
H
E
S
S
H
E
Site 55
S565
D
M
P
E
V
F
S
S
H
E
S
S
H
E
E
Site 56
S568
E
V
F
S
S
H
E
S
S
H
E
E
P
L
Q
Site 57
S569
V
F
S
S
H
E
S
S
H
E
E
P
L
Q
P
Site 58
S599
G
P
Q
P
A
L
K
S
R
Q
S
V
V
T
L
Site 59
S602
P
A
L
K
S
R
Q
S
V
V
T
L
Q
G
S
Site 60
T605
K
S
R
Q
S
V
V
T
L
Q
G
S
A
V
V
Site 61
S609
S
V
V
T
L
Q
G
S
A
V
V
A
N
R
T
Site 62
S636
G
Q
G
E
P
C
I
S
S
T
P
R
F
R
K
Site 63
S637
Q
G
E
P
C
I
S
S
T
P
R
F
R
K
V
Site 64
T638
G
E
P
C
I
S
S
T
P
R
F
R
K
V
V
Site 65
S649
R
K
V
V
R
Q
A
S
V
H
D
S
G
E
E
Site 66
S653
R
Q
A
S
V
H
D
S
G
E
E
G
E
A
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation