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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DCAF11
Full Name:
DDB1- and CUL4-associated factor 11
Alias:
WD repeat-containing protein 23
Type:
Mass (Da):
61670
Number AA:
546
UniProt ID:
Q8TEB1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
G
S
R
N
S
S
S
A
G
Site 2
S6
_
_
M
G
S
R
N
S
S
S
A
G
S
G
S
Site 3
S7
_
M
G
S
R
N
S
S
S
A
G
S
G
S
G
Site 4
S8
M
G
S
R
N
S
S
S
A
G
S
G
S
G
D
Site 5
S11
R
N
S
S
S
A
G
S
G
S
G
D
P
S
E
Site 6
S13
S
S
S
A
G
S
G
S
G
D
P
S
E
G
L
Site 7
S17
G
S
G
S
G
D
P
S
E
G
L
P
R
R
G
Site 8
S30
R
G
A
G
L
R
R
S
E
E
E
E
E
E
D
Site 9
S75
F
I
Q
A
L
L
D
S
E
E
E
N
D
R
A
Site 10
Y91
D
G
R
L
G
D
R
Y
N
P
P
V
D
A
T
Site 11
T98
Y
N
P
P
V
D
A
T
P
D
T
R
E
L
E
Site 12
T101
P
V
D
A
T
P
D
T
R
E
L
E
F
N
E
Site 13
S130
R
R
A
A
Q
K
H
S
F
P
R
M
L
H
Q
Site 14
S147
R
G
L
C
H
R
G
S
F
S
L
G
E
Q
S
Site 15
S149
L
C
H
R
G
S
F
S
L
G
E
Q
S
R
V
Site 16
S154
S
F
S
L
G
E
Q
S
R
V
I
S
H
F
L
Site 17
S158
G
E
Q
S
R
V
I
S
H
F
L
P
N
D
L
Site 18
S170
N
D
L
G
F
T
D
S
Y
S
Q
K
A
F
C
Site 19
Y171
D
L
G
F
T
D
S
Y
S
Q
K
A
F
C
G
Site 20
Y180
Q
K
A
F
C
G
I
Y
S
K
D
G
Q
I
F
Site 21
Y199
Q
D
Q
T
I
R
L
Y
D
C
R
Y
G
R
F
Site 22
Y203
I
R
L
Y
D
C
R
Y
G
R
F
R
K
F
K
Site 23
S211
G
R
F
R
K
F
K
S
I
K
A
R
D
V
G
Site 24
Y235
P
D
G
N
H
F
L
Y
S
S
W
S
D
Y
I
Site 25
Y241
L
Y
S
S
W
S
D
Y
I
H
I
C
N
I
Y
Site 26
T255
Y
G
E
G
D
T
H
T
A
L
D
L
R
P
D
Site 27
Y290
G
A
N
D
G
C
L
Y
V
F
D
R
E
Q
N
Site 28
T300
D
R
E
Q
N
R
R
T
L
Q
I
E
S
H
E
Site 29
T359
A
G
H
Q
D
G
I
T
F
I
D
S
K
G
D
Site 30
S363
D
G
I
T
F
I
D
S
K
G
D
A
R
Y
L
Site 31
Y369
D
S
K
G
D
A
R
Y
L
I
S
N
S
K
D
Site 32
S374
A
R
Y
L
I
S
N
S
K
D
Q
T
I
K
L
Site 33
T378
I
S
N
S
K
D
Q
T
I
K
L
W
D
I
R
Site 34
S388
L
W
D
I
R
R
F
S
S
R
E
G
M
E
A
Site 35
S389
W
D
I
R
R
F
S
S
R
E
G
M
E
A
S
Site 36
S427
L
K
L
P
G
D
S
S
L
M
T
Y
R
G
H
Site 37
T430
P
G
D
S
S
L
M
T
Y
R
G
H
G
V
L
Site 38
Y431
G
D
S
S
L
M
T
Y
R
G
H
G
V
L
H
Site 39
T439
R
G
H
G
V
L
H
T
L
I
R
C
R
F
S
Site 40
S446
T
L
I
R
C
R
F
S
P
I
H
S
T
G
Q
Site 41
Y457
S
T
G
Q
Q
F
I
Y
S
G
C
S
T
G
K
Site 42
S458
T
G
Q
Q
F
I
Y
S
G
C
S
T
G
K
V
Site 43
S490
K
A
C
V
R
D
V
S
W
H
P
F
E
E
K
Site 44
S500
P
F
E
E
K
I
V
S
S
S
W
D
G
N
L
Site 45
S502
E
E
K
I
V
S
S
S
W
D
G
N
L
R
L
Site 46
Y512
G
N
L
R
L
W
Q
Y
R
Q
A
E
Y
F
Q
Site 47
Y517
W
Q
Y
R
Q
A
E
Y
F
Q
D
D
M
P
E
Site 48
S525
F
Q
D
D
M
P
E
S
E
E
C
A
S
A
P
Site 49
S530
P
E
S
E
E
C
A
S
A
P
A
P
V
P
Q
Site 50
S538
A
P
A
P
V
P
Q
S
S
T
P
F
S
S
P
Site 51
S539
P
A
P
V
P
Q
S
S
T
P
F
S
S
P
Q
Site 52
T540
A
P
V
P
Q
S
S
T
P
F
S
S
P
Q
_
Site 53
S543
P
Q
S
S
T
P
F
S
S
P
Q
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation