KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
RHBDD1
Full Name:
Rhomboid domain-containing protein 1
Alias:
Type:
Mass (Da):
35823
Number AA:
315
UniProt ID:
Q8TEB9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y50
L
N
P
Q
K
P
L
Y
S
S
C
L
S
V
E
Site 2
S51
N
P
Q
K
P
L
Y
S
S
C
L
S
V
E
K
Site 3
S55
P
L
Y
S
S
C
L
S
V
E
K
C
Y
Q
Q
Site 4
S71
D
W
Q
R
L
L
L
S
P
L
H
H
A
D
D
Site 5
S101
N
L
E
R
R
L
G
S
R
W
F
A
Y
V
I
Site 6
S138
D
E
P
D
F
K
R
S
C
A
V
G
F
S
G
Site 7
Y157
L
K
V
L
N
N
H
Y
C
P
G
G
F
V
N
Site 8
S222
E
A
C
A
G
G
F
S
S
S
V
G
Y
P
G
Site 9
S223
A
C
A
G
G
F
S
S
S
V
G
Y
P
G
R
Site 10
S224
C
A
G
G
F
S
S
S
V
G
Y
P
G
R
Q
Site 11
Y227
G
F
S
S
S
V
G
Y
P
G
R
Q
Y
Y
F
Site 12
Y232
V
G
Y
P
G
R
Q
Y
Y
F
N
S
S
G
S
Site 13
Y233
G
Y
P
G
R
Q
Y
Y
F
N
S
S
G
S
S
Site 14
S236
G
R
Q
Y
Y
F
N
S
S
G
S
S
G
Y
Q
Site 15
S237
R
Q
Y
Y
F
N
S
S
G
S
S
G
Y
Q
D
Site 16
S240
Y
F
N
S
S
G
S
S
G
Y
Q
D
Y
Y
P
Site 17
Y242
N
S
S
G
S
S
G
Y
Q
D
Y
Y
P
H
G
Site 18
Y245
G
S
S
G
Y
Q
D
Y
Y
P
H
G
R
P
D
Site 19
Y246
S
S
G
Y
Q
D
Y
Y
P
H
G
R
P
D
H
Site 20
Y254
P
H
G
R
P
D
H
Y
E
E
A
P
R
N
Y
Site 21
Y261
Y
E
E
A
P
R
N
Y
D
T
Y
T
A
G
L
Site 22
T263
E
A
P
R
N
Y
D
T
Y
T
A
G
L
S
E
Site 23
Y264
A
P
R
N
Y
D
T
Y
T
A
G
L
S
E
E
Site 24
T265
P
R
N
Y
D
T
Y
T
A
G
L
S
E
E
E
Site 25
S269
D
T
Y
T
A
G
L
S
E
E
E
Q
L
E
R
Site 26
S281
L
E
R
A
L
Q
A
S
L
W
D
R
G
N
T
Site 27
T288
S
L
W
D
R
G
N
T
R
N
S
P
P
P
Y
Site 28
S291
D
R
G
N
T
R
N
S
P
P
P
Y
G
F
H
Site 29
Y295
T
R
N
S
P
P
P
Y
G
F
H
L
S
P
E
Site 30
S300
P
P
Y
G
F
H
L
S
P
E
E
M
R
R
Q
Site 31
S314
Q
R
L
H
R
F
D
S
Q
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation