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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SAP25
Full Name:
Histone deacetylase complex subunit SAP25
Alias:
25 kDa Sin3-associated polypeptide;Sin3 corepressor complex subunit SAP25
Type:
Mass (Da):
20873
Number AA:
199
UniProt ID:
Q8TEE9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y11
L
A
P
W
D
P
K
Y
E
A
K
A
G
P
R
Site 2
S26
P
V
W
G
A
N
C
S
S
G
A
S
F
S
G
Site 3
S27
V
W
G
A
N
C
S
S
G
A
S
F
S
G
R
Site 4
S30
A
N
C
S
S
G
A
S
F
S
G
R
T
L
C
Site 5
S32
C
S
S
G
A
S
F
S
G
R
T
L
C
H
P
Site 6
T35
G
A
S
F
S
G
R
T
L
C
H
P
S
F
W
Site 7
Y45
H
P
S
F
W
P
L
Y
E
A
A
S
G
R
G
Site 8
S49
W
P
L
Y
E
A
A
S
G
R
G
L
R
P
V
Site 9
Y98
R
G
Q
R
V
P
L
Y
L
S
K
A
P
Q
Q
Site 10
S100
Q
R
V
P
L
Y
L
S
K
A
P
Q
Q
M
M
Site 11
S109
A
P
Q
Q
M
M
G
S
L
K
L
L
P
P
P
Site 12
S120
L
P
P
P
P
I
M
S
A
R
V
L
P
R
P
Site 13
S128
A
R
V
L
P
R
P
S
P
S
R
G
P
S
T
Site 14
S130
V
L
P
R
P
S
P
S
R
G
P
S
T
A
W
Site 15
S134
P
S
P
S
R
G
P
S
T
A
W
L
S
G
P
Site 16
T135
S
P
S
R
G
P
S
T
A
W
L
S
G
P
E
Site 17
S153
L
T
G
L
L
Q
M
S
Q
G
E
P
R
P
S
Site 18
S160
S
Q
G
E
P
R
P
S
S
S
A
V
G
P
P
Site 19
S161
Q
G
E
P
R
P
S
S
S
A
V
G
P
P
D
Site 20
S162
G
E
P
R
P
S
S
S
A
V
G
P
P
D
H
Site 21
T170
A
V
G
P
P
D
H
T
S
D
P
P
S
P
C
Site 22
S171
V
G
P
P
D
H
T
S
D
P
P
S
P
C
G
Site 23
S175
D
H
T
S
D
P
P
S
P
C
G
S
P
S
S
Site 24
S179
D
P
P
S
P
C
G
S
P
S
S
S
Q
G
A
Site 25
S181
P
S
P
C
G
S
P
S
S
S
Q
G
A
D
L
Site 26
S182
S
P
C
G
S
P
S
S
S
Q
G
A
D
L
S
Site 27
S183
P
C
G
S
P
S
S
S
Q
G
A
D
L
S
L
Site 28
S189
S
S
Q
G
A
D
L
S
L
P
Q
T
P
D
T
Site 29
T193
A
D
L
S
L
P
Q
T
P
D
T
H
C
P
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation