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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SNED1
Full Name:
Sushi, nidogen and EGF-like domain-containing protein 1
Alias:
Insulin-responsive sequence DNA-binding protein 1; SST3
Type:
Uncharacterized
Mass (Da):
152204
Number AA:
1413
UniProt ID:
Q8TER0
International Prot ID:
IPI00152789
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0007160
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T43
A
E
R
G
D
A
V
T
P
K
Q
D
D
G
G
Site 2
S51
P
K
Q
D
D
G
G
S
G
L
R
P
L
S
V
Site 3
Y71
G
A
E
H
S
G
L
Y
V
N
N
N
G
I
I
Site 4
S79
V
N
N
N
G
I
I
S
F
L
K
E
V
S
Q
Site 5
Y117
N
R
R
A
G
D
V
Y
Y
R
E
A
T
D
P
Site 6
Y118
R
R
A
G
D
V
Y
Y
R
E
A
T
D
P
A
Site 7
T122
D
V
Y
Y
R
E
A
T
D
P
A
M
L
R
R
Site 8
T131
P
A
M
L
R
R
A
T
E
D
V
R
H
Y
F
Site 9
Y137
A
T
E
D
V
R
H
Y
F
P
E
L
L
D
F
Site 10
S163
R
V
T
F
F
G
G
S
S
S
S
P
V
N
T
Site 11
S165
T
F
F
G
G
S
S
S
S
P
V
N
T
F
Q
Site 12
S166
F
F
G
G
S
S
S
S
P
V
N
T
F
Q
T
Site 13
T173
S
P
V
N
T
F
Q
T
V
L
I
T
D
G
K
Site 14
T194
N
Y
E
S
I
V
W
T
T
G
T
H
A
S
S
Site 15
T197
S
I
V
W
T
T
G
T
H
A
S
S
G
G
N
Site 16
Y225
N
A
G
D
G
Q
R
Y
F
S
I
P
G
S
R
Site 17
S227
G
D
G
Q
R
Y
F
S
I
P
G
S
R
T
A
Site 18
S231
R
Y
F
S
I
P
G
S
R
T
A
D
M
A
E
Site 19
T242
D
M
A
E
V
E
T
T
T
N
V
G
V
P
G
Site 20
T290
K
C
I
D
D
C
V
T
G
N
P
S
Y
T
C
Site 21
S298
G
N
P
S
Y
T
C
S
C
L
S
G
F
T
G
Site 22
S317
L
D
V
N
E
C
A
S
Q
P
C
Q
N
G
G
Site 23
S351
P
T
C
E
T
A
Q
S
P
C
D
T
K
E
C
Site 24
T355
T
A
Q
S
P
C
D
T
K
E
C
Q
H
G
G
Site 25
S392
E
M
D
V
D
D
C
S
P
D
P
C
L
N
G
Site 26
T424
F
K
G
L
R
C
E
T
G
D
H
P
V
P
D
Site 27
S435
P
V
P
D
A
C
L
S
A
P
C
H
N
G
G
Site 28
Y451
C
V
D
A
D
Q
G
Y
V
C
E
C
P
E
G
Site 29
Y519
T
Q
C
P
D
G
G
Y
C
M
E
H
G
G
S
Site 30
S540
T
D
H
N
A
S
H
S
L
P
S
P
C
D
S
Site 31
S543
N
A
S
H
S
L
P
S
P
C
D
S
D
P
C
Site 32
S547
S
L
P
S
P
C
D
S
D
P
C
F
N
G
G
Site 33
Y563
C
D
A
H
D
D
S
Y
T
C
E
C
P
R
G
Site 34
T564
D
A
H
D
D
S
Y
T
C
E
C
P
R
G
F
Site 35
S585
K
A
R
P
H
L
C
S
S
G
P
C
R
N
G
Site 36
S586
A
R
P
H
L
C
S
S
G
P
C
R
N
G
G
Site 37
Y602
C
K
E
A
G
G
E
Y
H
C
S
C
P
Y
R
Site 38
S622
C
E
I
G
K
P
D
S
C
A
S
G
P
C
H
Site 39
S625
G
K
P
D
S
C
A
S
G
P
C
H
N
G
G
Site 40
S659
R
H
C
E
I
A
P
S
P
C
F
R
S
P
C
Site 41
S664
A
P
S
P
C
F
R
S
P
C
V
N
G
G
T
Site 42
T708
P
E
E
V
K
H
A
T
L
R
F
N
G
T
R
Site 43
Y728
L
Y
A
C
D
R
G
Y
S
L
S
A
P
S
R
Site 44
S729
Y
A
C
D
R
G
Y
S
L
S
A
P
S
R
I
Site 45
S731
C
D
R
G
Y
S
L
S
A
P
S
R
I
R
V
Site 46
S734
G
Y
S
L
S
A
P
S
R
I
R
V
C
Q
P
Site 47
S759
L
E
I
D
E
C
R
S
Q
P
C
L
H
G
G
Site 48
S805
H
P
C
R
N
G
G
S
C
R
N
L
P
G
A
Site 49
S835
T
E
V
D
A
C
D
S
S
P
C
Q
H
G
G
Site 50
S836
E
V
D
A
C
D
S
S
P
C
Q
H
G
G
R
Site 51
S846
Q
H
G
G
R
C
E
S
G
G
G
A
Y
L
C
Site 52
Y862
C
P
E
S
F
F
G
Y
H
C
E
T
V
S
D
Site 53
S868
G
Y
H
C
E
T
V
S
D
P
C
F
S
S
P
Site 54
S873
T
V
S
D
P
C
F
S
S
P
C
G
G
R
G
Site 55
S874
V
S
D
P
C
F
S
S
P
C
G
G
R
G
Y
Site 56
Y881
S
P
C
G
G
R
G
Y
C
L
A
S
N
G
S
Site 57
S885
G
R
G
Y
C
L
A
S
N
G
S
H
S
C
T
Site 58
S890
L
A
S
N
G
S
H
S
C
T
C
K
V
G
Y
Site 59
T892
S
N
G
S
H
S
C
T
C
K
V
G
Y
T
G
Site 60
S920
K
M
E
R
V
E
E
S
G
V
S
I
S
W
N
Site 61
S923
R
V
E
E
S
G
V
S
I
S
W
N
P
P
N
Site 62
S925
E
E
S
G
V
S
I
S
W
N
P
P
N
G
P
Site 63
Y941
A
R
Q
M
L
D
G
Y
A
V
T
Y
V
S
S
Site 64
T944
M
L
D
G
Y
A
V
T
Y
V
S
S
D
G
S
Site 65
Y945
L
D
G
Y
A
V
T
Y
V
S
S
D
G
S
Y
Site 66
S947
G
Y
A
V
T
Y
V
S
S
D
G
S
Y
R
R
Site 67
S951
T
Y
V
S
S
D
G
S
Y
R
R
T
D
F
V
Site 68
Y952
Y
V
S
S
D
G
S
Y
R
R
T
D
F
V
D
Site 69
T955
S
D
G
S
Y
R
R
T
D
F
V
D
R
T
R
Site 70
T961
R
T
D
F
V
D
R
T
R
S
S
H
Q
L
Q
Site 71
S963
D
F
V
D
R
T
R
S
S
H
Q
L
Q
A
L
Site 72
S964
F
V
D
R
T
R
S
S
H
Q
L
Q
A
L
A
Site 73
S979
A
G
R
A
Y
N
I
S
V
F
S
V
K
R
N
Site 74
S982
A
Y
N
I
S
V
F
S
V
K
R
N
S
N
N
Site 75
S987
V
F
S
V
K
R
N
S
N
N
K
N
D
I
S
Site 76
S1022
N
V
T
A
S
T
I
S
V
Q
W
A
L
H
R
Site 77
T1034
L
H
R
I
R
H
A
T
V
S
G
V
R
V
S
Site 78
S1036
R
I
R
H
A
T
V
S
G
V
R
V
S
I
R
Site 79
T1053
E
A
L
R
D
Q
A
T
D
V
D
R
S
V
D
Site 80
S1058
Q
A
T
D
V
D
R
S
V
D
R
F
T
F
R
Site 81
T1063
D
R
S
V
D
R
F
T
F
R
A
L
L
P
G
Site 82
Y1073
A
L
L
P
G
K
R
Y
T
I
Q
L
T
T
L
Site 83
T1078
K
R
Y
T
I
Q
L
T
T
L
S
G
L
R
G
Site 84
T1090
L
R
G
E
E
H
P
T
E
S
L
A
T
A
P
Site 85
S1092
G
E
E
H
P
T
E
S
L
A
T
A
P
T
H
Site 86
T1141
E
A
Y
V
I
N
V
T
T
S
Q
S
T
K
S
Site 87
S1143
Y
V
I
N
V
T
T
S
Q
S
T
K
S
R
Y
Site 88
Y1150
S
Q
S
T
K
S
R
Y
V
P
N
G
K
L
A
Site 89
Y1159
P
N
G
K
L
A
S
Y
T
V
R
D
L
L
P
Site 90
T1160
N
G
K
L
A
S
Y
T
V
R
D
L
L
P
G
Site 91
S1173
P
G
R
R
Y
Q
L
S
V
I
A
V
Q
S
T
Site 92
S1187
T
E
L
G
P
Q
H
S
E
P
A
H
L
Y
I
Site 93
Y1193
H
S
E
P
A
H
L
Y
I
I
T
S
P
R
D
Site 94
S1197
A
H
L
Y
I
I
T
S
P
R
D
G
A
D
R
Site 95
S1235
L
R
L
L
N
D
H
S
A
P
E
T
P
T
Q
Site 96
T1239
N
D
H
S
A
P
E
T
P
T
Q
P
P
R
F
Site 97
T1241
H
S
A
P
E
T
P
T
Q
P
P
R
F
S
E
Site 98
S1247
P
T
Q
P
P
R
F
S
E
L
V
D
G
R
G
Site 99
S1257
V
D
G
R
G
R
V
S
A
R
F
G
G
S
P
Site 100
S1263
V
S
A
R
F
G
G
S
P
S
K
A
A
T
V
Site 101
S1265
A
R
F
G
G
S
P
S
K
A
A
T
V
R
S
Site 102
T1269
G
S
P
S
K
A
A
T
V
R
S
Q
P
T
A
Site 103
S1272
S
K
A
A
T
V
R
S
Q
P
T
A
S
A
Q
Site 104
S1291
E
E
A
P
K
R
V
S
L
A
L
Q
L
P
E
Site 105
S1301
L
Q
L
P
E
H
G
S
K
D
I
G
N
V
P
Site 106
S1330
V
P
G
A
D
A
H
S
C
D
C
G
P
G
F
Site 107
T1354
I
K
V
S
R
P
C
T
R
L
F
S
E
T
K
Site 108
S1358
R
P
C
T
R
L
F
S
E
T
K
A
F
P
V
Site 109
T1360
C
T
R
L
F
S
E
T
K
A
F
P
V
W
E
Site 110
Y1375
G
G
V
C
H
H
V
Y
K
R
V
Y
R
V
H
Site 111
S1390
Q
D
I
C
F
K
E
S
C
E
S
T
S
L
K
Site 112
S1393
C
F
K
E
S
C
E
S
T
S
L
K
K
T
P
Site 113
T1394
F
K
E
S
C
E
S
T
S
L
K
K
T
P
N
Site 114
S1395
K
E
S
C
E
S
T
S
L
K
K
T
P
N
R
Site 115
T1399
E
S
T
S
L
K
K
T
P
N
R
K
Q
S
K
Site 116
S1405
K
T
P
N
R
K
Q
S
K
S
Q
T
L
E
K
Site 117
S1407
P
N
R
K
Q
S
K
S
Q
T
L
E
K
S
_
Site 118
T1409
R
K
Q
S
K
S
Q
T
L
E
K
S
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation