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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FBF1
Full Name:
Fas-binding factor 1
Alias:
fas (TNFRSF6) binding 1; Fas (TNFRSF6) binding factor 1; fas-binding 1; FBF-1; FLJ00103
Type:
Mass (Da):
125450
Number AA:
UniProt ID:
Q8TES7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
E
K
P
V
K
L
A
S
H
T
R
D
T
T
G
Site 2
T27
L
A
S
H
T
R
D
T
T
G
V
S
Q
M
F
Site 3
T28
A
S
H
T
R
D
T
T
G
V
S
Q
M
F
P
Site 4
S31
T
R
D
T
T
G
V
S
Q
M
F
P
S
S
K
Site 5
S37
V
S
Q
M
F
P
S
S
K
A
R
T
K
S
L
Site 6
T41
F
P
S
S
K
A
R
T
K
S
L
L
G
D
D
Site 7
S43
S
S
K
A
R
T
K
S
L
L
G
D
D
V
F
Site 8
S94
D
I
L
G
L
K
K
S
N
S
A
P
S
K
K
Site 9
S96
L
G
L
K
K
S
N
S
A
P
S
K
K
A
A
Site 10
S127
G
A
I
P
T
K
K
S
L
P
S
P
S
S
S
Site 11
S130
P
T
K
K
S
L
P
S
P
S
S
S
G
H
Q
Site 12
S132
K
K
S
L
P
S
P
S
S
S
G
H
Q
N
R
Site 13
S133
K
S
L
P
S
P
S
S
S
G
H
Q
N
R
R
Site 14
S134
S
L
P
S
P
S
S
S
G
H
Q
N
R
R
F
Site 15
S142
G
H
Q
N
R
R
F
S
S
E
D
L
E
D
P
Site 16
S143
H
Q
N
R
R
F
S
S
E
D
L
E
D
P
L
Site 17
S155
D
P
L
R
G
L
L
S
Y
D
E
G
G
I
T
Site 18
Y156
P
L
R
G
L
L
S
Y
D
E
G
G
I
T
K
Site 19
T162
S
Y
D
E
G
G
I
T
K
Q
P
P
V
T
Q
Site 20
T168
I
T
K
Q
P
P
V
T
Q
S
K
T
A
S
D
Site 21
S170
K
Q
P
P
V
T
Q
S
K
T
A
S
D
K
S
Site 22
T172
P
P
V
T
Q
S
K
T
A
S
D
K
S
P
S
Site 23
S174
V
T
Q
S
K
T
A
S
D
K
S
P
S
T
V
Site 24
S177
S
K
T
A
S
D
K
S
P
S
T
V
R
D
Q
Site 25
T180
A
S
D
K
S
P
S
T
V
R
D
Q
G
P
S
Site 26
S187
T
V
R
D
Q
G
P
S
I
P
L
T
P
G
D
Site 27
T191
Q
G
P
S
I
P
L
T
P
G
D
T
P
I
R
Site 28
T195
I
P
L
T
P
G
D
T
P
I
R
K
K
E
E
Site 29
T214
D
G
D
D
I
M
A
T
L
G
F
G
D
S
P
Site 30
S220
A
T
L
G
F
G
D
S
P
K
A
E
K
R
Q
Site 31
S239
E
G
P
R
P
A
R
S
T
L
D
E
L
L
G
Site 32
T240
G
P
R
P
A
R
S
T
L
D
E
L
L
G
R
Site 33
T259
K
L
L
A
R
P
G
T
G
E
H
R
E
F
K
Site 34
Y271
E
F
K
L
D
K
K
Y
Q
R
P
Q
D
S
E
Site 35
S277
K
Y
Q
R
P
Q
D
S
E
D
M
W
G
D
E
Site 36
T294
T
F
G
A
Y
Q
P
T
V
V
S
S
E
G
R
Site 37
S298
Y
Q
P
T
V
V
S
S
E
G
R
Q
S
R
R
Site 38
S303
V
S
S
E
G
R
Q
S
R
R
Q
S
V
S
R
Site 39
S307
G
R
Q
S
R
R
Q
S
V
S
R
F
F
A
D
Site 40
S309
Q
S
R
R
Q
S
V
S
R
F
F
A
D
S
G
Site 41
S315
V
S
R
F
F
A
D
S
G
A
D
P
K
G
E
Site 42
S325
D
P
K
G
E
P
G
S
K
Q
S
P
P
M
A
Site 43
S328
G
E
P
G
S
K
Q
S
P
P
M
A
S
S
P
Site 44
S333
K
Q
S
P
P
M
A
S
S
P
I
Q
P
R
K
Site 45
S334
Q
S
P
P
M
A
S
S
P
I
Q
P
R
K
G
Site 46
S359
D
L
D
L
F
P
A
S
P
T
R
E
A
H
R
Site 47
S368
T
R
E
A
H
R
E
S
S
V
P
V
T
P
S
Site 48
S369
R
E
A
H
R
E
S
S
V
P
V
T
P
S
V
Site 49
T373
R
E
S
S
V
P
V
T
P
S
V
P
P
P
A
Site 50
S375
S
S
V
P
V
T
P
S
V
P
P
P
A
S
Q
Site 51
S381
P
S
V
P
P
P
A
S
Q
H
S
T
P
A
G
Site 52
S384
P
P
P
A
S
Q
H
S
T
P
A
G
L
P
P
Site 53
T385
P
P
A
S
Q
H
S
T
P
A
G
L
P
P
S
Site 54
S392
T
P
A
G
L
P
P
S
R
A
K
P
P
T
E
Site 55
T398
P
S
R
A
K
P
P
T
E
G
A
G
S
P
A
Site 56
S403
P
P
T
E
G
A
G
S
P
A
K
A
S
Q
A
Site 57
S408
A
G
S
P
A
K
A
S
Q
A
S
K
L
R
A
Site 58
S416
Q
A
S
K
L
R
A
S
K
E
E
K
E
D
W
Site 59
S425
E
E
K
E
D
W
L
S
H
A
L
S
R
K
K
Site 60
S429
D
W
L
S
H
A
L
S
R
K
K
S
Q
G
L
Site 61
S433
H
A
L
S
R
K
K
S
Q
G
L
A
R
E
Q
Site 62
T453
E
G
L
H
L
A
G
T
A
G
H
P
P
S
G
Site 63
S459
G
T
A
G
H
P
P
S
G
S
Q
P
L
T
S
Site 64
S461
A
G
H
P
P
S
G
S
Q
P
L
T
S
T
Q
Site 65
T465
P
S
G
S
Q
P
L
T
S
T
Q
G
L
E
H
Site 66
T482
A
G
G
S
S
G
T
T
A
R
E
R
P
C
V
Site 67
S494
P
C
V
R
P
G
V
S
G
S
P
V
T
Q
N
Site 68
S496
V
R
P
G
V
S
G
S
P
V
T
Q
N
H
A
Site 69
S505
V
T
Q
N
H
A
A
S
A
L
P
T
G
S
P
Site 70
T509
H
A
A
S
A
L
P
T
G
S
P
K
R
G
T
Site 71
S511
A
S
A
L
P
T
G
S
P
K
R
G
T
A
P
Site 72
T516
T
G
S
P
K
R
G
T
A
P
G
D
L
S
A
Site 73
S522
G
T
A
P
G
D
L
S
A
T
E
P
A
T
C
Site 74
T528
L
S
A
T
E
P
A
T
C
F
P
S
T
Q
K
Site 75
S532
E
P
A
T
C
F
P
S
T
Q
K
P
T
E
P
Site 76
T533
P
A
T
C
F
P
S
T
Q
K
P
T
E
P
S
Site 77
S540
T
Q
K
P
T
E
P
S
V
P
V
Q
P
L
L
Site 78
S554
L
P
E
S
L
A
R
S
L
L
P
S
T
E
Y
Site 79
S558
L
A
R
S
L
L
P
S
T
E
Y
Q
K
Q
L
Site 80
T559
A
R
S
L
L
P
S
T
E
Y
Q
K
Q
L
L
Site 81
Y561
S
L
L
P
S
T
E
Y
Q
K
Q
L
L
A
A
Site 82
S575
A
Q
V
Q
L
Q
C
S
P
A
E
L
Q
A
E
Site 83
S627
A
D
L
E
L
I
E
S
A
H
R
S
R
I
K
Site 84
S631
L
I
E
S
A
H
R
S
R
I
K
V
L
E
T
Site 85
S655
R
R
E
N
E
E
L
S
A
R
Y
L
S
Q
C
Site 86
S660
E
L
S
A
R
Y
L
S
Q
C
Q
E
A
E
Q
Site 87
S701
L
R
E
L
Q
R
A
S
I
L
D
M
R
R
D
Site 88
T728
D
R
E
V
D
A
A
T
S
A
T
S
H
T
R
Site 89
S729
R
E
V
D
A
A
T
S
A
T
S
H
T
R
S
Site 90
S732
D
A
A
T
S
A
T
S
H
T
R
S
L
N
S
Site 91
S736
S
A
T
S
H
T
R
S
L
N
S
I
I
H
Q
Site 92
S749
H
Q
M
E
K
F
S
S
S
L
H
E
L
S
S
Site 93
S750
Q
M
E
K
F
S
S
S
L
H
E
L
S
S
R
Site 94
S755
S
S
S
L
H
E
L
S
S
R
V
E
A
S
H
Site 95
S756
S
S
L
H
E
L
S
S
R
V
E
A
S
H
L
Site 96
S761
L
S
S
R
V
E
A
S
H
L
T
T
S
Q
E
Site 97
S766
E
A
S
H
L
T
T
S
Q
E
R
E
L
G
I
Site 98
S799
R
D
M
E
E
E
R
S
R
Q
Q
E
V
I
G
Site 99
S816
E
A
R
L
N
E
Q
S
R
L
L
E
Q
E
R
Site 100
T827
E
Q
E
R
W
R
V
T
A
E
Q
S
K
A
E
Site 101
S835
A
E
Q
S
K
A
E
S
M
Q
R
A
L
E
E
Site 102
T847
L
E
E
Q
R
K
V
T
A
Q
Q
M
A
M
E
Site 103
S863
A
E
L
E
R
A
K
S
A
L
L
E
E
Q
K
Site 104
S871
A
L
L
E
E
Q
K
S
V
M
L
K
C
G
E
Site 105
T913
E
R
A
L
Q
V
D
T
Q
R
E
G
T
L
I
Site 106
T918
V
D
T
Q
R
E
G
T
L
I
S
L
A
K
Q
Site 107
S921
Q
R
E
G
T
L
I
S
L
A
K
Q
A
E
L
Site 108
S933
A
E
L
K
I
R
A
S
E
L
R
A
E
E
K
Site 109
S979
L
R
A
E
E
V
E
S
M
S
K
V
A
S
E
Site 110
S981
A
E
E
V
E
S
M
S
K
V
A
S
E
K
Y
Site 111
S985
E
S
M
S
K
V
A
S
E
K
Y
E
E
G
E
Site 112
Y988
S
K
V
A
S
E
K
Y
E
E
G
E
R
A
L
Site 113
S1032
H
M
H
Q
E
H
L
S
L
A
Q
Q
R
L
Q
Site 114
S1049
R
A
R
Q
D
L
P
S
S
L
V
G
L
F
P
Site 115
S1050
A
R
Q
D
L
P
S
S
L
V
G
L
F
P
R
Site 116
S1064
R
A
Q
G
P
A
A
S
S
Q
S
A
L
M
P
Site 117
S1065
A
Q
G
P
A
A
S
S
Q
S
A
L
M
P
P
Site 118
T1075
A
L
M
P
P
A
P
T
T
R
W
C
S
Q
P
Site 119
T1076
L
M
P
P
A
P
T
T
R
W
C
S
Q
P
P
Site 120
S1080
A
P
T
T
R
W
C
S
Q
P
P
T
G
L
D
Site 121
T1084
R
W
C
S
Q
P
P
T
G
L
D
P
S
P
L
Site 122
S1089
P
P
T
G
L
D
P
S
P
L
H
L
H
A
R
Site 123
T1120
N
E
Q
F
F
L
E
T
L
K
K
G
S
Y
N
Site 124
Y1126
E
T
L
K
K
G
S
Y
N
L
T
S
H
S
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation