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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GANC
Full Name:
Neutral alpha-glucosidase C
Alias:
Type:
Mass (Da):
104334
Number AA:
914
UniProt ID:
Q8TET4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
A
A
V
K
E
E
I
S
V
E
D
E
A
V
D
Site 2
Y30
D
C
N
K
I
A
F
Y
R
R
Q
K
Q
W
L
Site 3
S38
R
R
Q
K
Q
W
L
S
K
K
S
T
Y
R
A
Site 4
S41
K
Q
W
L
S
K
K
S
T
Y
R
A
L
L
D
Site 5
T42
Q
W
L
S
K
K
S
T
Y
R
A
L
L
D
S
Site 6
S49
T
Y
R
A
L
L
D
S
V
T
T
D
E
D
S
Site 7
T51
R
A
L
L
D
S
V
T
T
D
E
D
S
T
R
Site 8
T52
A
L
L
D
S
V
T
T
D
E
D
S
T
R
F
Site 9
S56
S
V
T
T
D
E
D
S
T
R
F
Q
I
I
N
Site 10
T90
R
L
K
I
N
E
E
T
P
L
K
P
R
F
E
Site 11
T103
F
E
V
P
D
V
L
T
S
K
P
S
T
V
R
Site 12
S104
E
V
P
D
V
L
T
S
K
P
S
T
V
R
L
Site 13
S113
P
S
T
V
R
L
I
S
C
S
G
D
T
G
S
Site 14
S120
S
C
S
G
D
T
G
S
L
I
L
A
D
G
K
Site 15
T135
G
D
L
K
C
H
I
T
A
N
P
F
K
V
D
Site 16
S181
K
E
N
E
E
E
T
S
V
D
T
S
Q
E
N
Site 17
S185
E
E
T
S
V
D
T
S
Q
E
N
Q
E
D
L
Site 18
Y226
L
H
G
F
E
H
L
Y
G
I
P
Q
H
A
E
Site 19
Y246
N
T
G
D
G
D
A
Y
R
L
Y
N
L
D
V
Site 20
Y249
D
G
D
A
Y
R
L
Y
N
L
D
V
Y
G
Y
Site 21
Y254
R
L
Y
N
L
D
V
Y
G
Y
Q
I
Y
D
K
Site 22
Y259
D
V
Y
G
Y
Q
I
Y
D
K
M
G
I
Y
G
Site 23
T320
K
Q
K
V
R
S
R
T
H
V
H
W
M
S
E
Site 24
S342
L
L
T
G
P
T
P
S
D
V
F
K
Q
Y
S
Site 25
Y348
P
S
D
V
F
K
Q
Y
S
H
L
T
G
T
Q
Site 26
Y392
F
D
E
H
D
I
P
Y
D
A
M
W
L
D
I
Site 27
Y407
E
H
T
E
G
K
R
Y
F
T
W
D
K
N
R
Site 28
T409
T
E
G
K
R
Y
F
T
W
D
K
N
R
F
P
Site 29
S427
R
M
Q
E
L
L
R
S
K
K
R
K
L
V
V
Site 30
Y446
H
I
K
I
D
P
D
Y
S
V
Y
V
K
A
K
Site 31
S447
I
K
I
D
P
D
Y
S
V
Y
V
K
A
K
D
Site 32
Y449
I
D
P
D
Y
S
V
Y
V
K
A
K
D
Q
G
Site 33
Y478
C
W
P
G
L
S
S
Y
L
D
F
T
N
P
K
Site 34
T482
L
S
S
Y
L
D
F
T
N
P
K
V
R
E
W
Site 35
Y490
N
P
K
V
R
E
W
Y
S
S
L
F
A
F
P
Site 36
S491
P
K
V
R
E
W
Y
S
S
L
F
A
F
P
V
Site 37
S492
K
V
R
E
W
Y
S
S
L
F
A
F
P
V
Y
Site 38
T524
V
F
R
G
P
E
Q
T
M
Q
K
N
A
I
H
Site 39
T570
K
E
R
P
F
V
L
T
R
S
F
F
A
G
S
Site 40
S572
R
P
F
V
L
T
R
S
F
F
A
G
S
Q
K
Site 41
S577
T
R
S
F
F
A
G
S
Q
K
Y
G
A
V
W
Site 42
Y580
F
F
A
G
S
Q
K
Y
G
A
V
W
T
G
D
Site 43
T589
A
V
W
T
G
D
N
T
A
E
W
S
N
L
K
Site 44
T626
G
F
I
G
N
P
E
T
E
L
L
V
R
W
Y
Site 45
Y633
T
E
L
L
V
R
W
Y
Q
A
G
A
Y
Q
P
Site 46
Y638
R
W
Y
Q
A
G
A
Y
Q
P
F
F
R
G
H
Site 47
T650
R
G
H
A
T
M
N
T
K
R
R
E
P
W
L
Site 48
Y674
R
E
A
I
R
E
R
Y
G
L
L
P
Y
W
Y
Site 49
Y679
E
R
Y
G
L
L
P
Y
W
Y
S
L
F
Y
H
Site 50
Y681
Y
G
L
L
P
Y
W
Y
S
L
F
Y
H
A
H
Site 51
Y685
P
Y
W
Y
S
L
F
Y
H
A
H
V
A
S
Q
Site 52
S691
F
Y
H
A
H
V
A
S
Q
P
V
M
R
P
L
Site 53
T708
E
F
P
D
E
L
K
T
F
D
M
E
D
E
Y
Site 54
Y746
P
G
S
N
E
V
W
Y
D
Y
K
T
F
A
H
Site 55
T750
E
V
W
Y
D
Y
K
T
F
A
H
W
E
G
G
Site 56
S788
I
K
T
T
V
G
K
S
T
G
W
M
T
E
S
Site 57
T793
G
K
S
T
G
W
M
T
E
S
S
Y
G
L
R
Site 58
S795
S
T
G
W
M
T
E
S
S
Y
G
L
R
V
A
Site 59
T805
G
L
R
V
A
L
S
T
K
G
S
S
V
G
E
Site 60
Y814
G
S
S
V
G
E
L
Y
L
D
D
G
H
S
F
Site 61
Y823
D
D
G
H
S
F
Q
Y
L
H
Q
K
Q
F
L
Site 62
S844
C
S
S
V
L
I
N
S
F
A
D
Q
R
G
H
Site 63
Y852
F
A
D
Q
R
G
H
Y
P
S
K
C
V
V
E
Site 64
S854
D
Q
R
G
H
Y
P
S
K
C
V
V
E
K
I
Site 65
S871
L
G
F
R
K
E
P
S
S
V
T
T
H
S
S
Site 66
S872
G
F
R
K
E
P
S
S
V
T
T
H
S
S
D
Site 67
T874
R
K
E
P
S
S
V
T
T
H
S
S
D
G
K
Site 68
T875
K
E
P
S
S
V
T
T
H
S
S
D
G
K
D
Site 69
S878
S
S
V
T
T
H
S
S
D
G
K
D
Q
P
V
Site 70
T888
K
D
Q
P
V
A
F
T
Y
C
A
K
T
S
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation