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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SFRS18
Full Name:
Splicing factor, arginine/serine-rich 18
Alias:
BA98I9.2; C6orf111; DKFZp564B0769; FLJ14752; Serine-arginine-rich-splicing regulatory protein 130; SFR17; SFR18; Splicing factor, arginine/serine-rich 130; SR-related protein; SR-rich protein
Type:
Unknown function
Mass (Da):
92577
Number AA:
805
UniProt ID:
Q8TF01
International Prot ID:
IPI00165995
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016607
GO:0016604
GO:0016607
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S48
W
I
A
Q
R
E
A
S
G
Q
Q
S
M
V
E
Site 2
S52
R
E
A
S
G
Q
Q
S
M
V
E
Q
P
P
G
Site 3
S68
M
P
N
G
Q
D
M
S
T
M
E
S
G
P
N
Site 4
T69
P
N
G
Q
D
M
S
T
M
E
S
G
P
N
N
Site 5
S72
Q
D
M
S
T
M
E
S
G
P
N
N
H
G
N
Site 6
T113
D
Q
P
W
M
P
P
T
P
G
P
M
D
I
V
Site 7
S123
P
M
D
I
V
P
P
S
E
D
S
N
S
Q
D
Site 8
S126
I
V
P
P
S
E
D
S
N
S
Q
D
S
G
E
Site 9
S128
P
P
S
E
D
S
N
S
Q
D
S
G
E
F
A
Site 10
Y166
G
P
V
N
Q
F
D
Y
Q
H
G
A
A
F
G
Site 11
Y183
Q
G
G
F
H
P
P
Y
W
Q
P
G
P
P
G
Site 12
S203
Q
N
R
R
E
R
P
S
S
F
R
D
R
Q
R
Site 13
S204
N
R
R
E
R
P
S
S
F
R
D
R
Q
R
S
Site 14
S211
S
F
R
D
R
Q
R
S
P
I
A
L
P
V
K
Site 15
T231
I
D
A
V
K
R
R
T
L
P
A
W
I
R
E
Site 16
S261
E
R
M
E
Q
Q
R
S
Q
L
S
K
K
E
K
Site 17
T271
S
K
K
E
K
K
A
T
E
D
A
E
G
G
D
Site 18
S286
G
P
R
L
P
Q
R
S
K
F
D
S
D
E
E
Site 19
S290
P
Q
R
S
K
F
D
S
D
E
E
E
E
D
T
Site 20
T297
S
D
E
E
E
E
D
T
E
N
V
E
A
A
S
Site 21
S304
T
E
N
V
E
A
A
S
S
G
K
V
T
R
S
Site 22
S305
E
N
V
E
A
A
S
S
G
K
V
T
R
S
P
Site 23
T309
A
A
S
S
G
K
V
T
R
S
P
S
P
V
P
Site 24
S311
S
S
G
K
V
T
R
S
P
S
P
V
P
Q
E
Site 25
S313
G
K
V
T
R
S
P
S
P
V
P
Q
E
E
H
Site 26
S321
P
V
P
Q
E
E
H
S
D
P
E
M
T
E
E
Site 27
T326
E
H
S
D
P
E
M
T
E
E
E
K
E
Y
Q
Site 28
Y332
M
T
E
E
E
K
E
Y
Q
M
M
L
L
T
K
Site 29
Y356
V
T
D
E
E
I
Y
Y
V
A
K
D
A
H
R
Site 30
T366
K
D
A
H
R
K
A
T
K
A
P
A
K
Q
L
Site 31
Y391
G
L
G
G
L
G
G
Y
G
S
G
D
S
E
D
Site 32
S393
G
G
L
G
G
Y
G
S
G
D
S
E
D
E
R
Site 33
S396
G
G
Y
G
S
G
D
S
E
D
E
R
S
D
R
Site 34
S401
G
D
S
E
D
E
R
S
D
R
G
S
E
S
S
Site 35
S405
D
E
R
S
D
R
G
S
E
S
S
D
T
D
D
Site 36
S408
S
D
R
G
S
E
S
S
D
T
D
D
E
E
L
Site 37
T410
R
G
S
E
S
S
D
T
D
D
E
E
L
R
H
Site 38
T448
M
E
E
E
K
Q
Q
T
E
R
V
T
K
E
M
Site 39
T452
K
Q
Q
T
E
R
V
T
K
E
M
N
E
F
I
Site 40
S465
F
I
H
K
E
Q
N
S
L
S
L
L
E
A
R
Site 41
S467
H
K
E
Q
N
S
L
S
L
L
E
A
R
E
A
Site 42
T485
V
V
N
E
K
K
R
T
P
N
E
T
T
S
V
Site 43
T489
K
K
R
T
P
N
E
T
T
S
V
L
E
P
K
Site 44
S508
E
K
E
K
Q
G
R
S
R
S
G
S
S
S
S
Site 45
S510
E
K
Q
G
R
S
R
S
G
S
S
S
S
G
S
Site 46
S512
Q
G
R
S
R
S
G
S
S
S
S
G
S
S
S
Site 47
S513
G
R
S
R
S
G
S
S
S
S
G
S
S
S
S
Site 48
S514
R
S
R
S
G
S
S
S
S
G
S
S
S
S
N
Site 49
S515
S
R
S
G
S
S
S
S
G
S
S
S
S
N
S
Site 50
S517
S
G
S
S
S
S
G
S
S
S
S
N
S
R
T
Site 51
S518
G
S
S
S
S
G
S
S
S
S
N
S
R
T
S
Site 52
S519
S
S
S
S
G
S
S
S
S
N
S
R
T
S
S
Site 53
S520
S
S
S
G
S
S
S
S
N
S
R
T
S
S
T
Site 54
S522
S
G
S
S
S
S
N
S
R
T
S
S
T
S
S
Site 55
T524
S
S
S
S
N
S
R
T
S
S
T
S
S
T
V
Site 56
S525
S
S
S
N
S
R
T
S
S
T
S
S
T
V
S
Site 57
S526
S
S
N
S
R
T
S
S
T
S
S
T
V
S
S
Site 58
T527
S
N
S
R
T
S
S
T
S
S
T
V
S
S
S
Site 59
S528
N
S
R
T
S
S
T
S
S
T
V
S
S
S
S
Site 60
S529
S
R
T
S
S
T
S
S
T
V
S
S
S
S
Y
Site 61
T530
R
T
S
S
T
S
S
T
V
S
S
S
S
Y
S
Site 62
S532
S
S
T
S
S
T
V
S
S
S
S
Y
S
S
S
Site 63
S533
S
T
S
S
T
V
S
S
S
S
Y
S
S
S
S
Site 64
S534
T
S
S
T
V
S
S
S
S
Y
S
S
S
S
G
Site 65
S535
S
S
T
V
S
S
S
S
Y
S
S
S
S
G
S
Site 66
Y536
S
T
V
S
S
S
S
Y
S
S
S
S
G
S
S
Site 67
S537
T
V
S
S
S
S
Y
S
S
S
S
G
S
S
R
Site 68
S538
V
S
S
S
S
Y
S
S
S
S
G
S
S
R
T
Site 69
S539
S
S
S
S
Y
S
S
S
S
G
S
S
R
T
S
Site 70
S540
S
S
S
Y
S
S
S
S
G
S
S
R
T
S
S
Site 71
S542
S
Y
S
S
S
S
G
S
S
R
T
S
S
R
S
Site 72
S543
Y
S
S
S
S
G
S
S
R
T
S
S
R
S
S
Site 73
T545
S
S
S
G
S
S
R
T
S
S
R
S
S
S
P
Site 74
S546
S
S
G
S
S
R
T
S
S
R
S
S
S
P
K
Site 75
S547
S
G
S
S
R
T
S
S
R
S
S
S
P
K
R
Site 76
S549
S
S
R
T
S
S
R
S
S
S
P
K
R
K
K
Site 77
S550
S
R
T
S
S
R
S
S
S
P
K
R
K
K
R
Site 78
S551
R
T
S
S
R
S
S
S
P
K
R
K
K
R
H
Site 79
S559
P
K
R
K
K
R
H
S
R
S
R
S
P
T
I
Site 80
S561
R
K
K
R
H
S
R
S
R
S
P
T
I
K
A
Site 81
S563
K
R
H
S
R
S
R
S
P
T
I
K
A
R
R
Site 82
T565
H
S
R
S
R
S
P
T
I
K
A
R
R
S
R
Site 83
S571
P
T
I
K
A
R
R
S
R
S
R
S
Y
S
R
Site 84
S573
I
K
A
R
R
S
R
S
R
S
Y
S
R
R
I
Site 85
S575
A
R
R
S
R
S
R
S
Y
S
R
R
I
K
I
Site 86
Y576
R
R
S
R
S
R
S
Y
S
R
R
I
K
I
E
Site 87
S577
R
S
R
S
R
S
Y
S
R
R
I
K
I
E
S
Site 88
S584
S
R
R
I
K
I
E
S
N
R
A
R
V
K
I
Site 89
S597
K
I
R
D
R
R
R
S
N
R
N
S
I
E
R
Site 90
S601
R
R
R
S
N
R
N
S
I
E
R
E
R
R
R
Site 91
S611
R
E
R
R
R
N
R
S
P
S
R
E
R
R
R
Site 92
S613
R
R
R
N
R
S
P
S
R
E
R
R
R
S
R
Site 93
S619
P
S
R
E
R
R
R
S
R
S
R
S
R
D
R
Site 94
S621
R
E
R
R
R
S
R
S
R
S
R
D
R
R
T
Site 95
S623
R
R
R
S
R
S
R
S
R
D
R
R
T
N
R
Site 96
T628
S
R
S
R
D
R
R
T
N
R
A
S
R
S
R
Site 97
S632
D
R
R
T
N
R
A
S
R
S
R
S
R
D
R
Site 98
S634
R
T
N
R
A
S
R
S
R
S
R
D
R
R
K
Site 99
S636
N
R
A
S
R
S
R
S
R
D
R
R
K
I
D
Site 100
S650
D
D
Q
R
G
N
L
S
G
N
S
H
K
H
K
Site 101
S653
R
G
N
L
S
G
N
S
H
K
H
K
G
E
A
Site 102
S670
Q
E
R
K
K
E
R
S
R
S
I
D
K
D
R
Site 103
S672
R
K
K
E
R
S
R
S
I
D
K
D
R
K
K
Site 104
S706
E
K
D
F
K
F
S
S
Q
D
D
R
L
K
R
Site 105
S717
R
L
K
R
K
R
E
S
E
R
T
F
S
R
S
Site 106
T720
R
K
R
E
S
E
R
T
F
S
R
S
G
S
I
Site 107
S722
R
E
S
E
R
T
F
S
R
S
G
S
I
S
V
Site 108
S724
S
E
R
T
F
S
R
S
G
S
I
S
V
K
I
Site 109
S726
R
T
F
S
R
S
G
S
I
S
V
K
I
I
R
Site 110
S728
F
S
R
S
G
S
I
S
V
K
I
I
R
H
D
Site 111
S736
V
K
I
I
R
H
D
S
R
Q
D
S
K
K
S
Site 112
S740
R
H
D
S
R
Q
D
S
K
K
S
T
T
K
D
Site 113
S743
S
R
Q
D
S
K
K
S
T
T
K
D
S
K
K
Site 114
T744
R
Q
D
S
K
K
S
T
T
K
D
S
K
K
H
Site 115
S748
K
K
S
T
T
K
D
S
K
K
H
S
G
S
D
Site 116
S752
T
K
D
S
K
K
H
S
G
S
D
S
S
G
R
Site 117
S754
D
S
K
K
H
S
G
S
D
S
S
G
R
S
S
Site 118
S756
K
K
H
S
G
S
D
S
S
G
R
S
S
S
E
Site 119
S757
K
H
S
G
S
D
S
S
G
R
S
S
S
E
S
Site 120
S760
G
S
D
S
S
G
R
S
S
S
E
S
P
G
S
Site 121
S761
S
D
S
S
G
R
S
S
S
E
S
P
G
S
S
Site 122
S762
D
S
S
G
R
S
S
S
E
S
P
G
S
S
K
Site 123
S764
S
G
R
S
S
S
E
S
P
G
S
S
K
E
K
Site 124
S767
S
S
S
E
S
P
G
S
S
K
E
K
K
A
K
Site 125
S768
S
S
E
S
P
G
S
S
K
E
K
K
A
K
K
Site 126
S779
K
A
K
K
P
K
H
S
R
S
R
S
V
E
K
Site 127
S781
K
K
P
K
H
S
R
S
R
S
V
E
K
S
Q
Site 128
S783
P
K
H
S
R
S
R
S
V
E
K
S
Q
R
S
Site 129
S787
R
S
R
S
V
E
K
S
Q
R
S
G
K
K
A
Site 130
S795
Q
R
S
G
K
K
A
S
R
K
H
K
S
K
S
Site 131
S800
K
A
S
R
K
H
K
S
K
S
R
S
R
_
_
Site 132
S802
S
R
K
H
K
S
K
S
R
S
R
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation