KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZNF721
Full Name:
Zinc finger protein 721
Alias:
KIAA1982; Zinc finger 721; ZN721
Type:
Unknown function
Mass (Da):
105080
Number AA:
UniProt ID:
Q8TF20
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
P
V
Q
G
I
E
D
S
F
H
K
L
I
L
R
Site 2
Y27
H
K
L
I
L
R
R
Y
E
K
C
G
H
D
N
Site 3
Y54
C
K
V
Q
K
G
V
Y
N
G
I
N
K
C
L
Site 4
S62
N
G
I
N
K
C
L
S
N
T
Q
S
K
I
F
Site 5
S79
N
A
R
V
K
V
F
S
K
F
A
N
S
N
K
Site 6
S84
V
F
S
K
F
A
N
S
N
K
D
K
T
R
H
Site 7
T89
A
N
S
N
K
D
K
T
R
H
T
G
E
K
H
Site 8
T92
N
K
D
K
T
R
H
T
G
E
K
H
F
K
C
Site 9
S110
G
K
S
F
Q
K
F
S
D
L
T
Q
H
K
G
Site 10
T113
F
Q
K
F
S
D
L
T
Q
H
K
G
I
H
A
Site 11
T126
H
A
G
E
K
P
Y
T
C
E
E
R
G
K
D
Site 12
Y137
R
G
K
D
F
G
W
Y
T
D
L
N
Q
H
K
Site 13
T148
N
Q
H
K
K
I
H
T
G
E
K
P
Y
K
C
Site 14
S165
C
G
K
A
F
N
R
S
T
N
L
T
A
H
K
Site 15
T166
G
K
A
F
N
R
S
T
N
L
T
A
H
K
R
Site 16
T169
F
N
R
S
T
N
L
T
A
H
K
R
I
H
N
Site 17
T182
H
N
R
E
K
A
Y
T
G
E
D
R
D
R
A
Site 18
Y209
I
H
T
G
D
K
P
Y
K
C
K
E
C
G
K
Site 19
S222
G
K
A
F
M
H
S
S
H
L
N
K
H
E
K
Site 20
T232
N
K
H
E
K
I
H
T
G
E
K
P
Y
K
C
Site 21
Y237
I
H
T
G
E
K
P
Y
K
C
K
E
C
G
K
Site 22
S247
K
E
C
G
K
V
I
S
S
S
S
S
F
A
K
Site 23
S248
E
C
G
K
V
I
S
S
S
S
S
F
A
K
H
Site 24
S249
C
G
K
V
I
S
S
S
S
S
F
A
K
H
K
Site 25
S250
G
K
V
I
S
S
S
S
S
F
A
K
H
K
R
Site 26
S251
K
V
I
S
S
S
S
S
F
A
K
H
K
R
I
Site 27
T260
A
K
H
K
R
I
H
T
G
E
K
P
F
K
C
Site 28
T281
F
N
I
S
T
T
L
T
K
H
R
R
I
H
T
Site 29
T288
T
K
H
R
R
I
H
T
G
E
K
P
Y
T
C
Site 30
T294
H
T
G
E
K
P
Y
T
C
E
V
C
G
K
A
Site 31
Y309
F
R
Q
S
A
N
L
Y
V
H
R
R
I
H
T
Site 32
T316
Y
V
H
R
R
I
H
T
G
E
K
P
Y
T
C
Site 33
Y321
I
H
T
G
E
K
P
Y
T
C
G
E
C
G
K
Site 34
T322
H
T
G
E
K
P
Y
T
C
G
E
C
G
K
T
Site 35
T329
T
C
G
E
C
G
K
T
F
R
Q
S
A
N
L
Site 36
T344
Y
V
H
R
R
I
H
T
G
E
K
P
Y
K
C
Site 37
Y361
C
G
K
A
F
G
R
Y
T
A
L
N
Q
H
K
Site 38
T362
G
K
A
F
G
R
Y
T
A
L
N
Q
H
K
K
Site 39
S388
E
C
G
K
A
F
N
S
S
T
N
L
T
A
H
Site 40
S389
C
G
K
A
F
N
S
S
T
N
L
T
A
H
K
Site 41
T393
F
N
S
S
T
N
L
T
A
H
K
R
I
H
T
Site 42
T400
T
A
H
K
R
I
H
T
R
E
K
P
Y
T
C
Site 43
T406
H
T
R
E
K
P
Y
T
C
E
D
R
G
R
A
Site 44
S417
R
G
R
A
F
G
L
S
T
N
L
N
E
Y
K
Site 45
T471
K
Q
C
G
K
V
I
T
S
S
S
S
F
A
K
Site 46
S472
Q
C
G
K
V
I
T
S
S
S
S
F
A
K
H
Site 47
S473
C
G
K
V
I
T
S
S
S
S
F
A
K
H
K
Site 48
S474
G
K
V
I
T
S
S
S
S
F
A
K
H
K
R
Site 49
S475
K
V
I
T
S
S
S
S
F
A
K
H
K
R
I
Site 50
T484
A
K
H
K
R
I
H
T
G
E
K
P
F
E
C
Site 51
T499
L
E
C
G
K
A
F
T
S
S
T
T
L
T
K
Site 52
S501
C
G
K
A
F
T
S
S
T
T
L
T
K
H
R
Site 53
T505
F
T
S
S
T
T
L
T
K
H
R
R
I
H
T
Site 54
Y533
F
R
Q
S
A
I
L
Y
V
H
R
R
I
H
T
Site 55
Y545
I
H
T
G
E
K
P
Y
T
C
E
E
C
G
K
Site 56
T546
H
T
G
E
K
P
Y
T
C
E
E
C
G
K
T
Site 57
T553
T
C
E
E
C
G
K
T
F
R
Q
S
A
N
L
Site 58
Y585
C
G
K
A
F
G
R
Y
T
D
L
N
Q
H
K
Site 59
T586
G
K
A
F
G
R
Y
T
D
L
N
Q
H
K
K
Site 60
T596
N
Q
H
K
K
I
H
T
G
E
K
L
Y
K
C
Site 61
Y601
I
H
T
G
E
K
L
Y
K
C
E
E
C
G
K
Site 62
Y613
C
G
K
D
F
V
W
Y
T
D
L
N
Q
Q
K
Site 63
Y623
L
N
Q
Q
K
K
I
Y
T
G
E
K
P
Y
K
Site 64
Y629
I
Y
T
G
E
K
P
Y
K
C
E
E
C
G
K
Site 65
T642
G
K
A
F
A
P
S
T
D
L
N
Q
H
T
K
Site 66
T652
N
Q
H
T
K
I
L
T
G
E
Q
S
Y
K
C
Site 67
S656
K
I
L
T
G
E
Q
S
Y
K
C
E
E
C
G
Site 68
S695
E
E
C
G
K
A
F
S
R
S
R
N
L
T
T
Site 69
S697
C
G
K
A
F
S
R
S
R
N
L
T
T
H
R
Site 70
T701
F
S
R
S
R
N
L
T
T
H
R
R
V
H
T
Site 71
T702
S
R
S
R
N
L
T
T
H
R
R
V
H
T
R
Site 72
T708
T
T
H
R
R
V
H
T
R
E
K
P
Y
K
C
Site 73
S721
K
C
E
D
R
G
R
S
F
G
W
S
T
N
L
Site 74
S725
R
G
R
S
F
G
W
S
T
N
L
N
E
Y
K
Site 75
Y741
I
H
T
G
D
K
L
Y
K
C
K
E
C
G
K
Site 76
S754
G
K
V
F
K
Q
S
S
H
L
N
R
H
E
K
Site 77
T779
K
E
C
G
K
V
I
T
S
S
S
S
F
A
K
Site 78
S780
E
C
G
K
V
I
T
S
S
S
S
F
A
K
H
Site 79
T826
H
T
G
E
K
P
Y
T
C
E
E
C
G
K
A
Site 80
Y869
F
R
Q
S
A
N
L
Y
A
H
K
K
I
H
T
Site 81
T876
Y
A
H
K
K
I
H
T
G
E
K
P
Y
T
C
Site 82
T882
H
T
G
E
K
P
Y
T
C
G
D
C
G
K
T
Site 83
T889
T
C
G
D
C
G
K
T
F
R
Q
S
A
N
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation