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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AGAP11
Full Name:
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 11
Alias:
Centaurin-gamma-like protein KIAA1975
Type:
Mass (Da):
60549
Number AA:
550
UniProt ID:
Q8TF27
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
T
E
R
D
A
D
R
S
L
T
I
L
D
E
Q
Site 2
T24
R
D
A
D
R
S
L
T
I
L
D
E
Q
L
Y
Site 3
Y31
T
I
L
D
E
Q
L
Y
S
F
A
F
S
T
V
Site 4
S36
Q
L
Y
S
F
A
F
S
T
V
H
I
T
K
K
Site 5
T37
L
Y
S
F
A
F
S
T
V
H
I
T
K
K
R
Site 6
T41
A
F
S
T
V
H
I
T
K
K
R
N
G
G
G
Site 7
S49
K
K
R
N
G
G
G
S
L
N
N
Y
S
S
S
Site 8
Y53
G
G
G
S
L
N
N
Y
S
S
S
I
P
L
T
Site 9
S54
G
G
S
L
N
N
Y
S
S
S
I
P
L
T
P
Site 10
S55
G
S
L
N
N
Y
S
S
S
I
P
L
T
P
S
Site 11
S56
S
L
N
N
Y
S
S
S
I
P
L
T
P
S
T
Site 12
T60
Y
S
S
S
I
P
L
T
P
S
T
S
Q
E
D
Site 13
S62
S
S
I
P
L
T
P
S
T
S
Q
E
D
L
Y
Site 14
T63
S
I
P
L
T
P
S
T
S
Q
E
D
L
Y
F
Site 15
S64
I
P
L
T
P
S
T
S
Q
E
D
L
Y
F
S
Site 16
Y69
S
T
S
Q
E
D
L
Y
F
S
V
P
P
T
A
Site 17
S71
S
Q
E
D
L
Y
F
S
V
P
P
T
A
N
T
Site 18
T78
S
V
P
P
T
A
N
T
P
T
P
I
C
K
Q
Site 19
T80
P
P
T
A
N
T
P
T
P
I
C
K
Q
S
M
Site 20
T94
M
G
W
S
N
L
F
T
S
E
K
G
S
D
P
Site 21
S95
G
W
S
N
L
F
T
S
E
K
G
S
D
P
D
Site 22
S99
L
F
T
S
E
K
G
S
D
P
D
K
G
R
K
Site 23
S110
K
G
R
K
A
L
E
S
H
A
D
T
I
G
S
Site 24
T114
A
L
E
S
H
A
D
T
I
G
S
G
R
A
I
Site 25
S117
S
H
A
D
T
I
G
S
G
R
A
I
P
I
K
Site 26
T138
R
S
G
K
W
L
K
T
W
K
K
K
Y
V
T
Site 27
Y143
L
K
T
W
K
K
K
Y
V
T
L
C
S
N
G
Site 28
T145
T
W
K
K
K
Y
V
T
L
C
S
N
G
V
L
Site 29
Y154
C
S
N
G
V
L
T
Y
Y
S
S
L
G
D
Y
Site 30
Y155
S
N
G
V
L
T
Y
Y
S
S
L
G
D
Y
M
Site 31
S157
G
V
L
T
Y
Y
S
S
L
G
D
Y
M
K
N
Site 32
Y161
Y
Y
S
S
L
G
D
Y
M
K
N
I
H
K
K
Site 33
S175
K
E
I
D
L
R
T
S
T
I
K
V
P
G
K
Site 34
T176
E
I
D
L
R
T
S
T
I
K
V
P
G
K
W
Site 35
S185
K
V
P
G
K
W
P
S
L
A
T
S
A
C
A
Site 36
S195
T
S
A
C
A
P
I
S
S
S
K
S
N
G
L
Site 37
S196
S
A
C
A
P
I
S
S
S
K
S
N
G
L
S
Site 38
S197
A
C
A
P
I
S
S
S
K
S
N
G
L
S
K
Site 39
S199
A
P
I
S
S
S
K
S
N
G
L
S
K
D
M
Site 40
S203
S
S
K
S
N
G
L
S
K
D
M
E
A
L
H
Site 41
S215
A
L
H
M
S
A
N
S
D
I
G
L
G
D
S
Site 42
S228
D
S
I
C
F
S
P
S
I
S
S
T
T
S
P
Site 43
T232
F
S
P
S
I
S
S
T
T
S
P
K
L
N
L
Site 44
S234
P
S
I
S
S
T
T
S
P
K
L
N
L
P
P
Site 45
S242
P
K
L
N
L
P
P
S
P
H
A
N
K
K
K
Site 46
S255
K
K
H
L
K
K
K
S
T
N
N
L
K
D
D
Site 47
S304
A
W
V
Q
A
I
Q
S
Q
I
L
A
S
L
Q
Site 48
S309
I
Q
S
Q
I
L
A
S
L
Q
S
C
E
S
S
Site 49
S312
Q
I
L
A
S
L
Q
S
C
E
S
S
K
S
K
Site 50
S315
A
S
L
Q
S
C
E
S
S
K
S
K
S
Q
L
Site 51
S316
S
L
Q
S
C
E
S
S
K
S
K
S
Q
L
T
Site 52
S318
Q
S
C
E
S
S
K
S
K
S
Q
L
T
S
Q
Site 53
S320
C
E
S
S
K
S
K
S
Q
L
T
S
Q
S
E
Site 54
S324
K
S
K
S
Q
L
T
S
Q
S
E
A
M
A
L
Site 55
S326
K
S
Q
L
T
S
Q
S
E
A
M
A
L
Q
S
Site 56
S372
E
C
S
G
I
H
R
S
L
G
T
R
L
S
R
Site 57
S378
R
S
L
G
T
R
L
S
R
V
R
S
L
E
L
Site 58
S382
T
R
L
S
R
V
R
S
L
E
L
D
D
W
P
Site 59
S398
E
L
R
K
V
M
S
S
I
G
N
D
L
A
N
Site 60
S406
I
G
N
D
L
A
N
S
I
W
E
G
S
S
Q
Site 61
T416
E
G
S
S
Q
G
Q
T
K
P
S
I
E
S
T
Site 62
S419
S
Q
G
Q
T
K
P
S
I
E
S
T
R
E
E
Site 63
S422
Q
T
K
P
S
I
E
S
T
R
E
E
K
E
R
Site 64
T423
T
K
P
S
I
E
S
T
R
E
E
K
E
R
W
Site 65
Y435
E
R
W
I
R
S
K
Y
E
H
K
L
F
L
A
Site 66
T459
G
Q
H
L
L
R
A
T
A
D
E
D
L
R
T
Site 67
T482
S
R
E
E
V
N
E
T
C
G
E
G
D
G
C
Site 68
T526
A
H
G
N
T
A
L
T
Y
A
R
Q
A
S
S
Site 69
Y527
H
G
N
T
A
L
T
Y
A
R
Q
A
S
S
Q
Site 70
S532
L
T
Y
A
R
Q
A
S
S
Q
E
C
I
N
V
Site 71
S533
T
Y
A
R
Q
A
S
S
Q
E
C
I
N
V
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation