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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF431
Full Name:
Zinc finger protein 431
Alias:
KIAA1969; Zinc finger 431; ZN431
Type:
Intracellular, Nucleus protein
Mass (Da):
67217
Number AA:
576
UniProt ID:
Q8TF32
International Prot ID:
IPI00328207
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y6
_
_
M
D
D
L
K
Y
G
V
Y
P
L
K
E
Site 2
Y9
D
D
L
K
Y
G
V
Y
P
L
K
E
A
S
G
Site 3
S15
V
Y
P
L
K
E
A
S
G
C
P
G
A
E
R
Site 4
Y27
A
E
R
N
L
L
V
Y
S
Y
F
E
K
E
T
Site 5
S28
E
R
N
L
L
V
Y
S
Y
F
E
K
E
T
L
Site 6
Y29
R
N
L
L
V
Y
S
Y
F
E
K
E
T
L
T
Site 7
T36
Y
F
E
K
E
T
L
T
F
R
D
V
A
I
E
Site 8
S45
R
D
V
A
I
E
F
S
L
E
E
W
E
C
L
Site 9
Y60
N
P
A
Q
Q
N
L
Y
M
N
V
M
L
E
N
Site 10
T85
V
S
K
Q
D
P
V
T
C
L
E
Q
E
K
E
Site 11
Y111
E
P
P
A
M
C
S
Y
F
T
K
D
L
W
P
Site 12
S125
P
E
Q
D
I
K
D
S
F
Q
Q
V
I
L
R
Site 13
Y134
Q
Q
V
I
L
R
R
Y
G
K
C
E
H
E
N
Site 14
S148
N
L
Q
L
R
K
G
S
A
S
V
D
E
Y
K
Site 15
S150
Q
L
R
K
G
S
A
S
V
D
E
Y
K
V
H
Site 16
Y154
G
S
A
S
V
D
E
Y
K
V
H
K
E
G
Y
Site 17
T169
N
E
L
N
Q
C
L
T
T
T
Q
S
K
I
F
Site 18
Y181
K
I
F
P
C
D
K
Y
V
K
V
F
H
K
F
Site 19
T196
L
N
A
N
R
H
K
T
R
H
T
G
K
K
P
Site 20
T199
N
R
H
K
T
R
H
T
G
K
K
P
F
K
C
Site 21
Y232
I
H
I
R
E
N
S
Y
Q
C
E
E
C
G
K
Site 22
S245
G
K
A
F
K
W
F
S
T
L
T
R
H
K
R
Site 23
T255
T
R
H
K
R
I
H
T
G
E
K
P
F
K
C
Site 24
S272
C
G
K
A
F
K
Q
S
S
T
L
T
T
H
K
Site 25
S273
G
K
A
F
K
Q
S
S
T
L
T
T
H
K
I
Site 26
T276
F
K
Q
S
S
T
L
T
T
H
K
I
I
H
T
Site 27
T277
K
Q
S
S
T
L
T
T
H
K
I
I
H
T
G
Site 28
T283
T
T
H
K
I
I
H
T
G
E
K
P
Y
R
C
Site 29
S300
C
G
K
A
F
N
R
S
S
H
L
T
T
H
K
Site 30
S301
G
K
A
F
N
R
S
S
H
L
T
T
H
K
I
Site 31
T304
F
N
R
S
S
H
L
T
T
H
K
I
I
H
T
Site 32
T311
T
T
H
K
I
I
H
T
G
E
K
P
Y
K
C
Site 33
Y316
I
H
T
G
E
K
P
Y
K
C
E
E
C
G
K
Site 34
S328
C
G
K
A
F
N
Q
S
S
T
L
S
T
H
K
Site 35
S329
G
K
A
F
N
Q
S
S
T
L
S
T
H
K
F
Site 36
T330
K
A
F
N
Q
S
S
T
L
S
T
H
K
F
I
Site 37
S332
F
N
Q
S
S
T
L
S
T
H
K
F
I
H
A
Site 38
T333
N
Q
S
S
T
L
S
T
H
K
F
I
H
A
G
Site 39
S357
D
K
A
F
N
R
F
S
Y
L
T
K
H
K
I
Site 40
Y358
K
A
F
N
R
F
S
Y
L
T
K
H
K
I
I
Site 41
S385
G
K
G
F
N
W
S
S
T
L
T
K
H
K
R
Site 42
T386
K
G
F
N
W
S
S
T
L
T
K
H
K
R
I
Site 43
T388
F
N
W
S
S
T
L
T
K
H
K
R
I
H
T
Site 44
T395
T
K
H
K
R
I
H
T
G
E
K
P
Y
K
C
Site 45
S412
C
G
K
A
F
N
E
S
S
N
L
T
T
H
K
Site 46
S413
G
K
A
F
N
E
S
S
N
L
T
T
H
K
M
Site 47
T416
F
N
E
S
S
N
L
T
T
H
K
M
I
H
T
Site 48
T423
T
T
H
K
M
I
H
T
G
E
K
P
Y
K
C
Site 49
S440
C
G
K
A
F
N
R
S
P
Q
L
T
A
H
K
Site 50
T444
F
N
R
S
P
Q
L
T
A
H
K
I
I
H
T
Site 51
T451
T
A
H
K
I
I
H
T
G
E
K
P
Y
K
C
Site 52
S466
E
E
C
G
K
A
F
S
Q
S
S
I
L
T
T
Site 53
S468
C
G
K
A
F
S
Q
S
S
I
L
T
T
H
K
Site 54
S469
G
K
A
F
S
Q
S
S
I
L
T
T
H
K
R
Site 55
T472
F
S
Q
S
S
I
L
T
T
H
K
R
I
H
T
Site 56
T473
S
Q
S
S
I
L
T
T
H
K
R
I
H
T
G
Site 57
T479
T
T
H
K
R
I
H
T
G
E
K
P
Y
K
C
Site 58
S496
C
G
K
A
F
N
R
S
S
N
L
T
K
H
K
Site 59
S497
G
K
A
F
N
R
S
S
N
L
T
K
H
K
I
Site 60
T500
F
N
R
S
S
N
L
T
K
H
K
I
I
H
T
Site 61
S525
G
K
A
F
N
Q
S
S
T
L
T
K
H
R
K
Site 62
T528
F
N
Q
S
S
T
L
T
K
H
R
K
I
H
T
Site 63
Y562
L
I
K
Q
N
N
S
Y
W
R
E
T
L
Q
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation