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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF483
Full Name:
Zinc finger protein 483
Alias:
Zinc finger protein with KRAB and SCAN domains 16
Type:
Mass (Da):
85098
Number AA:
744
UniProt ID:
Q8TF39
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
L
N
K
M
T
A
I
S
P
E
P
Q
T
L
A
Site 2
T19
A
I
S
P
E
P
Q
T
L
A
S
T
E
Q
N
Site 3
T33
N
E
V
P
R
V
V
T
S
G
E
Q
E
A
I
Site 4
S50
G
N
A
A
D
A
E
S
F
R
Q
R
F
R
W
Site 5
Y60
Q
R
F
R
W
F
C
Y
S
E
V
A
G
P
R
Site 6
S71
A
G
P
R
K
A
L
S
Q
L
W
E
L
C
N
Site 7
T87
W
L
R
P
D
I
H
T
K
E
Q
I
L
E
L
Site 8
S114
E
I
R
I
W
V
K
S
Q
H
P
E
S
S
E
Site 9
S119
V
K
S
Q
H
P
E
S
S
E
E
V
V
T
L
Site 10
S120
K
S
Q
H
P
E
S
S
E
E
V
V
T
L
I
Site 11
T125
E
S
S
E
E
V
V
T
L
I
E
D
L
T
Q
Site 12
T131
V
T
L
I
E
D
L
T
Q
M
L
E
E
K
D
Site 13
S141
L
E
E
K
D
P
V
S
Q
D
S
T
V
S
Q
Site 14
S144
K
D
P
V
S
Q
D
S
T
V
S
Q
E
E
N
Site 15
T145
D
P
V
S
Q
D
S
T
V
S
Q
E
E
N
S
Site 16
S147
V
S
Q
D
S
T
V
S
Q
E
E
N
S
K
E
Site 17
T159
S
K
E
D
K
M
V
T
V
C
P
N
T
E
S
Site 18
T164
M
V
T
V
C
P
N
T
E
S
C
E
S
I
T
Site 19
S166
T
V
C
P
N
T
E
S
C
E
S
I
T
L
K
Site 20
Y195
E
P
F
Q
K
E
L
Y
K
E
V
L
L
E
N
Site 21
S235
P
W
L
L
E
E
V
S
K
S
S
R
L
D
E
Site 22
S237
L
L
E
E
V
S
K
S
S
R
L
D
E
S
A
Site 23
S264
D
H
G
L
M
E
E
S
Q
Q
Y
C
G
S
S
Site 24
Y267
L
M
E
E
S
Q
Q
Y
C
G
S
S
E
E
D
Site 25
S270
E
S
Q
Q
Y
C
G
S
S
E
E
D
H
G
N
Site 26
S271
S
Q
Q
Y
C
G
S
S
E
E
D
H
G
N
Q
Site 27
T290
G
R
V
A
Q
N
K
T
L
G
S
G
S
R
G
Site 28
S293
A
Q
N
K
T
L
G
S
G
S
R
G
K
K
F
Site 29
S305
K
K
F
D
P
D
K
S
P
F
G
H
N
F
K
Site 30
Y324
L
I
K
H
L
R
V
Y
L
R
K
K
S
R
R
Site 31
S329
R
V
Y
L
R
K
K
S
R
R
Y
N
E
S
K
Site 32
Y332
L
R
K
K
S
R
R
Y
N
E
S
K
K
P
F
Site 33
S335
K
S
R
R
Y
N
E
S
K
K
P
F
S
F
H
Site 34
S340
N
E
S
K
K
P
F
S
F
H
S
D
L
V
L
Site 35
S358
E
K
T
A
G
E
K
S
R
K
S
N
D
G
G
Site 36
S361
A
G
E
K
S
R
K
S
N
D
G
G
K
V
L
Site 37
S369
N
D
G
G
K
V
L
S
H
S
S
A
L
T
E
Site 38
S371
G
G
K
V
L
S
H
S
S
A
L
T
E
H
Q
Site 39
T375
L
S
H
S
S
A
L
T
E
H
Q
K
R
Q
K
Site 40
S389
K
I
H
L
G
D
R
S
Q
K
C
S
K
C
G
Site 41
S403
G
I
I
F
I
R
R
S
T
L
S
R
R
K
T
Site 42
T404
I
I
F
I
R
R
S
T
L
S
R
R
K
T
P
Site 43
S406
F
I
R
R
S
T
L
S
R
R
K
T
P
M
C
Site 44
T410
S
T
L
S
R
R
K
T
P
M
C
E
K
C
R
Site 45
S420
C
E
K
C
R
K
D
S
C
Q
E
A
A
L
N
Site 46
T438
G
N
E
S
G
E
K
T
H
K
C
S
K
C
G
Site 47
S453
K
A
F
G
Y
S
A
S
L
T
K
H
R
R
I
Site 48
T455
F
G
Y
S
A
S
L
T
K
H
R
R
I
H
T
Site 49
T462
T
K
H
R
R
I
H
T
G
E
K
P
Y
M
C
Site 50
Y467
I
H
T
G
E
K
P
Y
M
C
N
E
C
G
K
Site 51
S477
N
E
C
G
K
A
F
S
D
S
S
S
L
T
P
Site 52
S479
C
G
K
A
F
S
D
S
S
S
L
T
P
H
H
Site 53
S480
G
K
A
F
S
D
S
S
S
L
T
P
H
H
R
Site 54
S481
K
A
F
S
D
S
S
S
L
T
P
H
H
R
T
Site 55
T483
F
S
D
S
S
S
L
T
P
H
H
R
T
H
S
Site 56
S490
T
P
H
H
R
T
H
S
G
E
K
P
F
K
C
Site 57
T505
D
D
C
G
K
G
F
T
L
S
A
H
L
I
K
Site 58
T518
I
K
H
Q
R
I
H
T
G
E
K
P
Y
K
C
Site 59
S533
K
D
C
G
R
P
F
S
D
S
S
S
L
I
Q
Site 60
S535
C
G
R
P
F
S
D
S
S
S
L
I
Q
H
Q
Site 61
S537
R
P
F
S
D
S
S
S
L
I
Q
H
Q
R
I
Site 62
T546
I
Q
H
Q
R
I
H
T
G
E
K
P
Y
T
C
Site 63
T552
H
T
G
E
K
P
Y
T
C
S
N
C
G
K
S
Site 64
S554
G
E
K
P
Y
T
C
S
N
C
G
K
S
F
S
Site 65
S559
T
C
S
N
C
G
K
S
F
S
H
S
S
S
L
Site 66
S561
S
N
C
G
K
S
F
S
H
S
S
S
L
S
K
Site 67
S563
C
G
K
S
F
S
H
S
S
S
L
S
K
H
Q
Site 68
S564
G
K
S
F
S
H
S
S
S
L
S
K
H
Q
R
Site 69
S565
K
S
F
S
H
S
S
S
L
S
K
H
Q
R
I
Site 70
S567
F
S
H
S
S
S
L
S
K
H
Q
R
I
H
T
Site 71
T574
S
K
H
Q
R
I
H
T
G
E
K
P
Y
K
C
Site 72
Y579
I
H
T
G
E
K
P
Y
K
C
G
E
C
G
K
Site 73
S592
G
K
A
F
R
Q
N
S
C
L
T
R
H
Q
R
Site 74
T602
T
R
H
Q
R
I
H
T
G
E
K
P
Y
L
C
Site 75
Y607
I
H
T
G
E
K
P
Y
L
C
N
D
C
G
M
Site 76
Y624
S
H
F
T
S
V
I
Y
H
Q
R
L
H
S
G
Site 77
S648
E
K
A
F
P
T
H
S
L
L
S
R
H
Q
R
Site 78
T658
S
R
H
Q
R
I
H
T
G
V
K
P
Y
K
C
Site 79
S671
K
C
K
E
C
G
K
S
F
S
Q
S
S
S
L
Site 80
S673
K
E
C
G
K
S
F
S
Q
S
S
S
L
N
E
Site 81
S675
C
G
K
S
F
S
Q
S
S
S
L
N
E
H
H
Site 82
S676
G
K
S
F
S
Q
S
S
S
L
N
E
H
H
R
Site 83
S677
K
S
F
S
Q
S
S
S
L
N
E
H
H
R
I
Site 84
T686
N
E
H
H
R
I
H
T
G
E
K
P
Y
E
C
Site 85
Y691
I
H
T
G
E
K
P
Y
E
C
N
Y
C
G
A
Site 86
Y695
E
K
P
Y
E
C
N
Y
C
G
A
T
F
S
R
Site 87
T699
E
C
N
Y
C
G
A
T
F
S
R
S
S
I
L
Site 88
S704
G
A
T
F
S
R
S
S
I
L
V
E
H
L
K
Site 89
T714
V
E
H
L
K
I
H
T
G
R
R
E
Y
E
C
Site 90
Y719
I
H
T
G
R
R
E
Y
E
C
N
E
C
E
K
Site 91
T727
E
C
N
E
C
E
K
T
F
K
S
N
S
G
L
Site 92
S730
E
C
E
K
T
F
K
S
N
S
G
L
I
R
H
Site 93
S732
E
K
T
F
K
S
N
S
G
L
I
R
H
R
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation