KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FNIP1
Full Name:
Folliculin-interacting protein 1
Alias:
Folliculin interacting protein 1; KIAA1961
Type:
Mass (Da):
130601
Number AA:
1166
UniProt ID:
Q8TF40
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
T
L
F
Q
K
L
F
S
K
R
T
G
L
G
A
Site 2
Y47
S
Q
I
R
L
I
V
Y
Q
D
C
E
R
R
G
Site 3
S62
R
N
V
L
F
D
S
S
V
K
R
R
N
E
D
Site 4
S71
K
R
R
N
E
D
I
S
V
S
K
L
C
S
D
Site 5
S73
R
N
E
D
I
S
V
S
K
L
C
S
D
A
Q
Site 6
S77
I
S
V
S
K
L
C
S
D
A
Q
V
K
V
F
Site 7
S96
Q
L
K
P
G
G
D
S
S
S
S
L
D
S
S
Site 8
S97
L
K
P
G
G
D
S
S
S
S
L
D
S
S
V
Site 9
S98
K
P
G
G
D
S
S
S
S
L
D
S
S
V
T
Site 10
S99
P
G
G
D
S
S
S
S
L
D
S
S
V
T
S
Site 11
S102
D
S
S
S
S
L
D
S
S
V
T
S
S
S
D
Site 12
S103
S
S
S
S
L
D
S
S
V
T
S
S
S
D
I
Site 13
T105
S
S
L
D
S
S
V
T
S
S
S
D
I
K
D
Site 14
S106
S
L
D
S
S
V
T
S
S
S
D
I
K
D
Q
Site 15
S107
L
D
S
S
V
T
S
S
S
D
I
K
D
Q
C
Site 16
S108
D
S
S
V
T
S
S
S
D
I
K
D
Q
C
L
Site 17
Y117
I
K
D
Q
C
L
K
Y
Q
G
S
R
C
S
S
Site 18
S120
Q
C
L
K
Y
Q
G
S
R
C
S
S
D
A
N
Site 19
S123
K
Y
Q
G
S
R
C
S
S
D
A
N
M
L
G
Site 20
S124
Y
Q
G
S
R
C
S
S
D
A
N
M
L
G
E
Site 21
S153
L
K
I
H
Q
I
R
S
P
P
Q
L
M
L
S
Site 22
S160
S
P
P
Q
L
M
L
S
K
V
F
T
A
R
T
Site 23
T167
S
K
V
F
T
A
R
T
G
S
S
I
C
G
S
Site 24
S169
V
F
T
A
R
T
G
S
S
I
C
G
S
L
N
Site 25
S170
F
T
A
R
T
G
S
S
I
C
G
S
L
N
T
Site 26
S174
T
G
S
S
I
C
G
S
L
N
T
L
Q
D
S
Site 27
T177
S
I
C
G
S
L
N
T
L
Q
D
S
L
E
F
Site 28
S181
S
L
N
T
L
Q
D
S
L
E
F
I
N
Q
D
Site 29
S210
L
L
G
N
I
G
L
S
Q
F
C
S
P
R
R
Site 30
S214
I
G
L
S
Q
F
C
S
P
R
R
A
F
S
E
Site 31
S220
C
S
P
R
R
A
F
S
E
Q
G
P
L
R
L
Site 32
S230
G
P
L
R
L
I
R
S
A
S
F
F
A
V
H
Site 33
S232
L
R
L
I
R
S
A
S
F
F
A
V
H
S
N
Site 34
S254
E
L
N
E
D
R
D
S
G
I
A
R
S
A
S
Site 35
S259
R
D
S
G
I
A
R
S
A
S
L
S
S
L
L
Site 36
S261
S
G
I
A
R
S
A
S
L
S
S
L
L
I
T
Site 37
S263
I
A
R
S
A
S
L
S
S
L
L
I
T
P
F
Site 38
S264
A
R
S
A
S
L
S
S
L
L
I
T
P
F
P
Site 39
S272
L
L
I
T
P
F
P
S
P
N
S
S
L
T
R
Site 40
S275
T
P
F
P
S
P
N
S
S
L
T
R
S
C
A
Site 41
S276
P
F
P
S
P
N
S
S
L
T
R
S
C
A
S
Site 42
T278
P
S
P
N
S
S
L
T
R
S
C
A
S
S
Y
Site 43
S280
P
N
S
S
L
T
R
S
C
A
S
S
Y
Q
R
Site 44
S284
L
T
R
S
C
A
S
S
Y
Q
R
R
W
R
R
Site 45
Y285
T
R
S
C
A
S
S
Y
Q
R
R
W
R
R
S
Site 46
S292
Y
Q
R
R
W
R
R
S
Q
T
T
S
L
E
N
Site 47
T294
R
R
W
R
R
S
Q
T
T
S
L
E
N
G
V
Site 48
T295
R
W
R
R
S
Q
T
T
S
L
E
N
G
V
F
Site 49
S296
W
R
R
S
Q
T
T
S
L
E
N
G
V
F
P
Site 50
S306
N
G
V
F
P
R
W
S
I
E
E
S
F
N
L
Site 51
S310
P
R
W
S
I
E
E
S
F
N
L
S
D
E
S
Site 52
S314
I
E
E
S
F
N
L
S
D
E
S
C
G
P
N
Site 53
S317
S
F
N
L
S
D
E
S
C
G
P
N
P
G
I
Site 54
S339
I
G
V
I
F
S
L
S
K
D
E
D
E
N
N
Site 55
S361
S
H
F
P
L
F
E
S
H
M
N
K
L
K
S
Site 56
S368
S
H
M
N
K
L
K
S
A
I
E
Q
A
M
K
Site 57
S377
I
E
Q
A
M
K
M
S
R
R
S
A
D
A
S
Site 58
S380
A
M
K
M
S
R
R
S
A
D
A
S
Q
R
S
Site 59
S384
S
R
R
S
A
D
A
S
Q
R
S
L
A
Y
N
Site 60
S387
S
A
D
A
S
Q
R
S
L
A
Y
N
R
I
V
Site 61
Y408
R
T
T
I
C
N
L
Y
T
M
P
R
I
G
E
Site 62
T409
T
T
I
C
N
L
Y
T
M
P
R
I
G
E
P
Site 63
T425
W
L
T
M
M
S
G
T
P
E
K
N
H
L
C
Site 64
S447
T
F
L
M
E
N
A
S
K
N
Q
F
L
P
A
Site 65
S487
I
F
L
E
K
H
S
S
Q
S
V
D
M
L
A
Site 66
T496
S
V
D
M
L
A
K
T
H
P
Y
N
P
L
W
Site 67
T522
S
P
V
R
L
A
R
T
V
V
V
G
K
R
Q
Site 68
S546
L
T
Y
F
I
R
C
S
E
L
Q
E
T
H
L
Site 69
T551
R
C
S
E
L
Q
E
T
H
L
L
E
N
G
E
Site 70
T572
P
G
T
V
I
T
T
T
L
E
K
G
E
I
E
Site 71
S581
E
K
G
E
I
E
E
S
E
Y
V
L
V
T
M
Site 72
Y583
G
E
I
E
E
S
E
Y
V
L
V
T
M
H
R
Site 73
S593
V
T
M
H
R
N
K
S
S
L
L
F
K
E
S
Site 74
S594
T
M
H
R
N
K
S
S
L
L
F
K
E
S
E
Site 75
S600
S
S
L
L
F
K
E
S
E
E
I
R
T
P
N
Site 76
T605
K
E
S
E
E
I
R
T
P
N
C
N
C
K
Y
Site 77
S614
N
C
N
C
K
Y
C
S
H
P
L
L
G
Q
N
Site 78
S644
S
K
E
L
L
G
I
S
D
E
C
Q
M
I
S
Site 79
S651
S
D
E
C
Q
M
I
S
P
S
D
C
Q
E
E
Site 80
S653
E
C
Q
M
I
S
P
S
D
C
Q
E
E
N
A
Site 81
T672
Q
Y
R
D
K
L
R
T
C
F
D
A
K
L
E
Site 82
S695
P
V
D
K
C
A
L
S
E
S
G
L
E
S
T
Site 83
S697
D
K
C
A
L
S
E
S
G
L
E
S
T
E
E
Site 84
S701
L
S
E
S
G
L
E
S
T
E
E
T
W
Q
S
Site 85
T705
G
L
E
S
T
E
E
T
W
Q
S
E
K
L
L
Site 86
S708
S
T
E
E
T
W
Q
S
E
K
L
L
D
S
D
Site 87
S714
Q
S
E
K
L
L
D
S
D
S
H
T
G
K
A
Site 88
S716
E
K
L
L
D
S
D
S
H
T
G
K
A
M
R
Site 89
T718
L
L
D
S
D
S
H
T
G
K
A
M
R
S
T
Site 90
T725
T
G
K
A
M
R
S
T
G
M
V
V
E
K
K
Site 91
S741
P
D
K
I
V
P
A
S
F
S
C
E
A
A
Q
Site 92
S758
V
T
F
L
I
G
D
S
M
S
P
D
S
D
T
Site 93
S760
F
L
I
G
D
S
M
S
P
D
S
D
T
E
L
Site 94
S763
G
D
S
M
S
P
D
S
D
T
E
L
R
S
Q
Site 95
T765
S
M
S
P
D
S
D
T
E
L
R
S
Q
A
V
Site 96
S769
D
S
D
T
E
L
R
S
Q
A
V
V
D
Q
I
Site 97
T781
D
Q
I
T
R
H
H
T
K
P
L
K
E
E
R
Site 98
T800
Q
H
Q
E
T
K
Q
T
T
K
D
Q
S
G
E
Site 99
T810
D
Q
S
G
E
S
D
T
Q
N
M
V
S
E
E
Site 100
S815
S
D
T
Q
N
M
V
S
E
E
P
C
E
L
P
Site 101
S827
E
L
P
C
W
N
H
S
D
P
E
S
M
S
L
Site 102
S833
H
S
D
P
E
S
M
S
L
F
D
E
Y
F
N
Site 103
Y838
S
M
S
L
F
D
E
Y
F
N
D
D
S
I
E
Site 104
S843
D
E
Y
F
N
D
D
S
I
E
T
R
T
I
D
Site 105
T856
I
D
D
V
P
F
K
T
S
T
D
S
K
D
H
Site 106
T858
D
V
P
F
K
T
S
T
D
S
K
D
H
C
C
Site 107
T908
P
Q
Q
D
Q
R
D
T
L
S
I
L
V
P
H
Site 108
S910
Q
D
Q
R
D
T
L
S
I
L
V
P
H
G
D
Site 109
S920
V
P
H
G
D
K
E
S
S
D
K
K
I
A
V
Site 110
S921
P
H
G
D
K
E
S
S
D
K
K
I
A
V
G
Site 111
S938
W
D
I
P
R
N
E
S
S
D
S
A
L
G
D
Site 112
S939
D
I
P
R
N
E
S
S
D
S
A
L
G
D
S
Site 113
S941
P
R
N
E
S
S
D
S
A
L
G
D
S
E
S
Site 114
S946
S
D
S
A
L
G
D
S
E
S
E
D
T
G
H
Site 115
S948
S
A
L
G
D
S
E
S
E
D
T
G
H
D
M
Site 116
T951
G
D
S
E
S
E
D
T
G
H
D
M
T
R
Q
Site 117
T956
E
D
T
G
H
D
M
T
R
Q
V
S
S
Y
Y
Site 118
S960
H
D
M
T
R
Q
V
S
S
Y
Y
G
G
E
Q
Site 119
Y962
M
T
R
Q
V
S
S
Y
Y
G
G
E
Q
E
D
Site 120
S981
D
E
I
P
F
P
G
S
K
L
I
E
V
S
A
Site 121
Y1004
G
R
S
L
L
G
G
Y
C
S
S
Y
V
P
D
Site 122
S1019
F
V
L
Q
G
I
G
S
D
E
R
F
R
Q
C
Site 123
S1029
R
F
R
Q
C
L
M
S
D
L
S
H
A
V
Q
Site 124
S1032
Q
C
L
M
S
D
L
S
H
A
V
Q
H
P
V
Site 125
T1058
I
A
D
M
D
K
W
T
V
Q
V
A
S
S
Q
Site 126
S1063
K
W
T
V
Q
V
A
S
S
Q
R
R
V
T
D
Site 127
S1064
W
T
V
Q
V
A
S
S
Q
R
R
V
T
D
N
Site 128
T1069
A
S
S
Q
R
R
V
T
D
N
K
L
G
K
E
Site 129
Y1094
L
H
S
T
L
Q
L
Y
K
H
N
L
S
P
N
Site 130
Y1115
E
D
R
L
Q
E
L
Y
F
K
S
K
M
L
S
Site 131
S1118
L
Q
E
L
Y
F
K
S
K
M
L
S
E
Y
L
Site 132
S1122
Y
F
K
S
K
M
L
S
E
Y
L
R
G
Q
M
Site 133
Y1124
K
S
K
M
L
S
E
Y
L
R
G
Q
M
R
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation