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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UBASH3B
Full Name:
Ubiquitin-associated and SH3 domain-containing protein B
Alias:
Cbl-interacting protein p70; Cbl-interacting protein Sts-1; KIAA1959; nm23-phosphorylated unknown substrate; SH3 domain-containing 70 kDa protein, suppressor of T-cell receptor signaling 1, nm23-phosphorylated unknown substrate; STS-1; suppressor of T-cell receptor signaling 1; ubiquitin associated and SH3 domain containing, B; ubiquitin associated and SH3 domain-containing protein B; UBS3B
Type:
Unknown function
Mass (Da):
72696
Number AA:
649
UniProt ID:
Q8TF42
International Prot ID:
IPI00154910
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
A
Q
Y
G
H
P
S
P
L
G
M
A
A
R
Site 2
Y19
M
A
A
R
E
E
L
Y
S
K
V
T
P
R
R
Site 3
S20
A
A
R
E
E
L
Y
S
K
V
T
P
R
R
N
Site 4
T23
E
E
L
Y
S
K
V
T
P
R
R
N
R
Q
Q
Site 5
T34
N
R
Q
Q
R
P
G
T
I
K
H
G
S
A
L
Site 6
Y90
D
D
P
L
P
R
E
Y
V
L
Y
L
R
P
T
Site 7
Y93
L
P
R
E
Y
V
L
Y
L
R
P
T
G
P
L
Site 8
S105
G
P
L
A
Q
K
L
S
D
F
W
Q
Q
S
K
Site 9
S138
Q
F
F
M
C
E
D
S
K
V
D
A
L
G
E
Site 10
T149
A
L
G
E
A
L
Q
T
T
V
S
R
W
K
C
Site 11
T150
L
G
E
A
L
Q
T
T
V
S
R
W
K
C
K
Site 12
S152
E
A
L
Q
T
T
V
S
R
W
K
C
K
F
S
Site 13
T226
F
Q
A
S
H
L
P
T
L
E
K
L
A
Q
N
Site 14
Y263
H
E
T
L
Q
V
I
Y
P
Y
T
P
Q
N
D
Site 15
T266
L
Q
V
I
Y
P
Y
T
P
Q
N
D
D
E
L
Site 16
S284
P
G
D
F
I
F
M
S
P
M
E
Q
T
S
T
Site 17
S290
M
S
P
M
E
Q
T
S
T
S
E
G
W
I
Y
Site 18
T291
S
P
M
E
Q
T
S
T
S
E
G
W
I
Y
G
Site 19
S292
P
M
E
Q
T
S
T
S
E
G
W
I
Y
G
T
Site 20
Y297
S
T
S
E
G
W
I
Y
G
T
S
L
T
T
G
Site 21
S300
E
G
W
I
Y
G
T
S
L
T
T
G
C
S
G
Site 22
Y313
S
G
L
L
P
E
N
Y
I
T
K
A
D
E
C
Site 23
T315
L
L
P
E
N
Y
I
T
K
A
D
E
C
S
T
Site 24
S330
W
I
F
H
G
S
Y
S
I
L
N
T
S
S
S
Site 25
T334
G
S
Y
S
I
L
N
T
S
S
S
N
S
L
T
Site 26
S335
S
Y
S
I
L
N
T
S
S
S
N
S
L
T
F
Site 27
S336
Y
S
I
L
N
T
S
S
S
N
S
L
T
F
G
Site 28
S337
S
I
L
N
T
S
S
S
N
S
L
T
F
G
D
Site 29
S339
L
N
T
S
S
S
N
S
L
T
F
G
D
G
V
Site 30
T341
T
S
S
S
N
S
L
T
F
G
D
G
V
L
E
Site 31
Y352
G
V
L
E
R
R
P
Y
E
D
Q
G
L
G
E
Site 32
S377
M
Q
P
L
R
V
N
S
Q
P
G
P
Q
K
R
Site 33
Y402
M
D
V
V
F
G
K
Y
W
L
S
Q
C
F
D
Site 34
Y414
C
F
D
A
K
G
R
Y
I
R
T
N
L
N
M
Site 35
T417
A
K
G
R
Y
I
R
T
N
L
N
M
P
H
S
Site 36
S424
T
N
L
N
M
P
H
S
L
P
Q
R
S
G
G
Site 37
Y435
R
S
G
G
F
R
D
Y
E
K
D
A
P
I
T
Site 38
Y467
N
T
I
I
D
H
V
Y
C
S
P
S
L
R
C
Site 39
T477
P
S
L
R
C
V
Q
T
A
H
N
I
L
K
G
Site 40
S526
E
L
A
A
A
N
L
S
V
D
T
T
Y
R
P
Site 41
T530
A
N
L
S
V
D
T
T
Y
R
P
H
I
P
I
Site 42
Y531
N
L
S
V
D
T
T
Y
R
P
H
I
P
I
S
Site 43
S538
Y
R
P
H
I
P
I
S
K
L
V
V
S
E
S
Site 44
S545
S
K
L
V
V
S
E
S
Y
D
T
Y
I
S
R
Site 45
T548
V
V
S
E
S
Y
D
T
Y
I
S
R
S
F
Q
Site 46
Y549
V
S
E
S
Y
D
T
Y
I
S
R
S
F
Q
V
Site 47
S553
Y
D
T
Y
I
S
R
S
F
Q
V
T
K
E
I
Site 48
T557
I
S
R
S
F
Q
V
T
K
E
I
I
S
E
C
Site 49
S562
Q
V
T
K
E
I
I
S
E
C
K
S
K
G
N
Site 50
S566
E
I
I
S
E
C
K
S
K
G
N
N
I
L
I
Site 51
S591
T
C
Q
L
Q
G
L
S
P
Q
N
S
K
D
F
Site 52
S595
Q
G
L
S
P
Q
N
S
K
D
F
V
Q
M
V
Site 53
T619
S
C
E
E
L
G
E
T
G
I
W
Q
L
T
D
Site 54
T633
D
P
P
I
L
P
L
T
H
G
P
T
G
G
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation