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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FBXO41
Full Name:
F-box only protein 41
Alias:
F-box protein 41; FBX41; FBX41 Gene Symbols:Â FBXO41; KIAA1940
Type:
Mass (Da):
94510
Number AA:
875
UniProt ID:
Q8TF61
International Prot ID:
IPI00291868
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0019941
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
A
S
L
D
L
P
Y
R
C
Site 2
Y8
M
A
S
L
D
L
P
Y
R
C
P
R
C
G
E
Site 3
S21
G
E
H
K
R
F
R
S
L
S
S
L
R
A
H
Site 4
S23
H
K
R
F
R
S
L
S
S
L
R
A
H
L
E
Site 5
S24
K
R
F
R
S
L
S
S
L
R
A
H
L
E
Y
Site 6
Y31
S
L
R
A
H
L
E
Y
S
H
T
Y
E
T
L
Site 7
S32
L
R
A
H
L
E
Y
S
H
T
Y
E
T
L
Y
Site 8
T34
A
H
L
E
Y
S
H
T
Y
E
T
L
Y
I
L
Site 9
Y39
S
H
T
Y
E
T
L
Y
I
L
S
K
T
N
S
Site 10
S86
A
R
R
E
V
F
E
S
T
S
F
Q
G
K
E
Site 11
S88
R
E
V
F
E
S
T
S
F
Q
G
K
E
Q
A
Site 12
S99
K
E
Q
A
A
G
P
S
P
A
A
P
H
L
L
Site 13
S162
G
E
L
F
A
R
K
S
V
A
S
S
A
C
S
Site 14
S165
F
A
R
K
S
V
A
S
S
A
C
S
T
P
P
Site 15
S166
A
R
K
S
V
A
S
S
A
C
S
T
P
P
P
Site 16
S169
S
V
A
S
S
A
C
S
T
P
P
P
G
P
G
Site 17
T170
V
A
S
S
A
C
S
T
P
P
P
G
P
G
P
Site 18
S185
G
P
C
P
G
P
A
S
A
S
P
A
S
P
S
Site 19
S187
C
P
G
P
A
S
A
S
P
A
S
P
S
P
A
Site 20
S190
P
A
S
A
S
P
A
S
P
S
P
A
D
V
A
Site 21
S192
S
A
S
P
A
S
P
S
P
A
D
V
A
Y
E
Site 22
Y198
P
S
P
A
D
V
A
Y
E
E
G
L
A
R
L
Site 23
S223
D
R
R
L
E
R
L
S
E
E
V
E
Q
K
I
Site 24
T250
R
K
A
A
E
L
E
T
A
R
Q
E
S
A
R
Site 25
S255
L
E
T
A
R
Q
E
S
A
R
L
G
R
E
K
Site 26
S270
E
E
L
E
E
R
A
S
E
L
S
R
Q
V
D
Site 27
S273
E
E
R
A
S
E
L
S
R
Q
V
D
V
S
V
Site 28
S298
V
H
K
E
Q
E
L
S
R
K
Q
Q
E
V
V
Site 29
S320
E
T
A
A
R
E
A
S
A
K
L
R
L
Q
Q
Site 30
S347
E
R
Q
L
Q
V
I
S
S
S
C
G
S
T
P
Site 31
S348
R
Q
L
Q
V
I
S
S
S
C
G
S
T
P
S
Site 32
S349
Q
L
Q
V
I
S
S
S
C
G
S
T
P
S
A
Site 33
T353
I
S
S
S
C
G
S
T
P
S
A
S
L
G
R
Site 34
S355
S
S
C
G
S
T
P
S
A
S
L
G
R
G
G
Site 35
S357
C
G
S
T
P
S
A
S
L
G
R
G
G
G
G
Site 36
T389
V
G
P
A
V
P
N
T
Y
A
V
S
R
H
G
Site 37
Y390
G
P
A
V
P
N
T
Y
A
V
S
R
H
G
S
Site 38
S393
V
P
N
T
Y
A
V
S
R
H
G
S
S
P
S
Site 39
S397
Y
A
V
S
R
H
G
S
S
P
S
T
G
A
S
Site 40
S398
A
V
S
R
H
G
S
S
P
S
T
G
A
S
S
Site 41
S400
S
R
H
G
S
S
P
S
T
G
A
S
S
R
V
Site 42
T401
R
H
G
S
S
P
S
T
G
A
S
S
R
V
P
Site 43
S404
S
S
P
S
T
G
A
S
S
R
V
P
A
A
S
Site 44
S405
S
P
S
T
G
A
S
S
R
V
P
A
A
S
Q
Site 45
S411
S
S
R
V
P
A
A
S
Q
S
S
G
C
Y
D
Site 46
S413
R
V
P
A
A
S
Q
S
S
G
C
Y
D
S
D
Site 47
Y417
A
S
Q
S
S
G
C
Y
D
S
D
S
L
E
L
Site 48
S419
Q
S
S
G
C
Y
D
S
D
S
L
E
L
P
R
Site 49
S421
S
G
C
Y
D
S
D
S
L
E
L
P
R
P
E
Site 50
S435
E
E
G
A
P
E
D
S
G
P
G
G
L
G
T
Site 51
S451
A
Q
A
A
N
G
G
S
E
R
T
Q
P
P
R
Site 52
T454
A
N
G
G
S
E
R
T
Q
P
P
R
S
S
G
Site 53
S459
E
R
T
Q
P
P
R
S
S
G
L
R
R
Q
A
Site 54
S460
R
T
Q
P
P
R
S
S
G
L
R
R
Q
A
I
Site 55
S478
Q
R
R
P
R
R
H
S
T
E
G
E
E
G
D
Site 56
T479
R
R
P
R
R
H
S
T
E
G
E
E
G
D
V
Site 57
S487
E
G
E
E
G
D
V
S
D
V
G
S
R
T
T
Site 58
S491
G
D
V
S
D
V
G
S
R
T
T
E
S
E
A
Site 59
T494
S
D
V
G
S
R
T
T
E
S
E
A
E
G
P
Site 60
S496
V
G
S
R
T
T
E
S
E
A
E
G
P
L
D
Site 61
S516
P
A
M
A
G
P
L
S
S
C
R
L
S
A
R
Site 62
S517
A
M
A
G
P
L
S
S
C
R
L
S
A
R
P
Site 63
S521
P
L
S
S
C
R
L
S
A
R
P
E
G
G
S
Site 64
S528
S
A
R
P
E
G
G
S
G
R
G
R
R
A
E
Site 65
S538
G
R
R
A
E
R
V
S
P
S
R
S
N
E
V
Site 66
S540
R
A
E
R
V
S
P
S
R
S
N
E
V
I
S
Site 67
S542
E
R
V
S
P
S
R
S
N
E
V
I
S
P
E
Site 68
S547
S
R
S
N
E
V
I
S
P
E
I
L
K
M
R
Site 69
S632
R
Q
R
G
K
K
E
S
K
E
E
Y
A
R
S
Site 70
Y636
K
K
E
S
K
E
E
Y
A
R
S
T
R
G
C
Site 71
S639
S
K
E
E
Y
A
R
S
T
R
G
C
L
E
A
Site 72
T640
K
E
E
Y
A
R
S
T
R
G
C
L
E
A
G
Site 73
T672
S
H
C
P
N
I
L
T
D
R
S
L
W
L
A
Site 74
T695
A
V
T
Y
R
S
A
T
D
P
V
G
H
E
V
Site 75
S762
C
G
V
Q
G
L
A
S
L
A
R
N
C
M
R
Site 76
S817
K
A
L
L
H
F
N
S
I
C
R
N
L
K
S
Site 77
Y834
V
Q
I
G
I
A
D
Y
F
K
E
P
S
S
P
Site 78
S840
D
Y
F
K
E
P
S
S
P
E
A
Q
K
L
F
Site 79
T852
K
L
F
E
D
M
V
T
K
L
Q
A
L
R
R
Site 80
S864
L
R
R
R
P
G
F
S
K
I
L
H
I
K
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation