PhosphoNET

           
Protein Info 
   
Short Name:  WIPF2
Full Name:  WAS/WASL-interacting protein family member 2
Alias:  WAS/WASL interacting protein family, member 2; WICH; WIRE
Type:  Adapter/scaffold protein
Mass (Da):  46289
Number AA:  440
UniProt ID:  Q8TF74
International Prot ID:  IPI00435947
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005856   Uniprot OncoNet
Molecular Function:  GO:0003779     PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T18PGPPPPPTFHQANTE
Site 2T24PTFHQANTEQPKLSR
Site 3S71LEKPKGSSGGYGSGG
Site 4Y74PKGSSGGYGSGGAAL
Site 5S76GSSGGYGSGGAALQP
Site 6S104PVGAKDGSENLAGKP
Site 7S117KPALQIPSSRAAAPR
Site 8S118PALQIPSSRAAAPRP
Site 9S128AAPRPPVSAASGRPQ
Site 10T138SGRPQDDTDSSRASL
Site 11S140RPQDDTDSSRASLPE
Site 12S141PQDDTDSSRASLPEL
Site 13S144DTDSSRASLPELPRM
Site 14S155LPRMQRPSLPDLSRP
Site 15S160RPSLPDLSRPNTTSS
Site 16T164PDLSRPNTTSSTGMK
Site 17S166LSRPNTTSSTGMKHS
Site 18S167SRPNTTSSTGMKHSS
Site 19T168RPNTTSSTGMKHSSS
Site 20S173SSTGMKHSSSAPPPP
Site 21S174STGMKHSSSAPPPPP
Site 22S175TGMKHSSSAPPPPPP
Site 23T191RRANAPPTPLPMHSS
Site 24S197PTPLPMHSSKAPAYN
Site 25S198TPLPMHSSKAPAYNR
Site 26Y203HSSKAPAYNREKPLP
Site 27T212REKPLPPTPGQRLHP
Site 28S235PPVKPPPSPVNIRTG
Site 29T241PSPVNIRTGPSGQSL
Site 30S247RTGPSGQSLAPPPPP
Site 31Y255LAPPPPPYRQPPGVP
Site 32S266PGVPNGPSSPTNESA
Site 33S267GVPNGPSSPTNESAP
Site 34T269PNGPSSPTNESAPEL
Site 35S272PSSPTNESAPELPQR
Site 36S282ELPQRHNSLHRKTPG
Site 37T287HNSLHRKTPGPVRGL
Site 38S301LAPPPPTSASPSLLS
Site 39S303PPPPTSASPSLLSNR
Site 40S305PPTSASPSLLSNRPP
Site 41S308SASPSLLSNRPPPPA
Site 42S320PPARDPPSRGAAPPP
Site 43Y346APPPPPPYRMHGSEP
Site 44S351PPYRMHGSEPPSRGK
Site 45S355MHGSEPPSRGKPPPP
Site 46S364GKPPPPPSRTPAGPP
Site 47T366PPPPPSRTPAGPPPP
Site 48S385LRNGHRDSITTVRSF
Site 49T387NGHRDSITTVRSFLD
Site 50T388GHRDSITTVRSFLDD
Site 51S391DSITTVRSFLDDFES
Site 52S398SFLDDFESKYSFHPV
Site 53Y400LDDFESKYSFHPVED
Site 54S401DDFESKYSFHPVEDF
Site 55Y414DFPAPEEYKHFQRIY
Site 56Y421YKHFQRIYPSKTNRA
Site 57S423HFQRIYPSKTNRAAR
Site 58T425QRIYPSKTNRAARGA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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