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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DUSP19
Full Name:
Dual specificity protein phosphatase 19
Alias:
Dual-specificity phosphatase TS-DSP1; EC 3.1.3.16; EC 3.1.3.48; LMW-DSP3; Protein phosphatase SKRP1; Stress-activated protein kinase pathway-regulating phosphatase 1
Type:
Protein phosphatase, dual-specificity
Mass (Da):
24194
Number AA:
217
UniProt ID:
Q8WTR2
International Prot ID:
IPI00102808
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0004725
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y2
_
_
_
_
_
_
M
Y
S
L
N
Q
E
I
K
Site 2
T24
R
K
Q
C
T
R
V
T
T
L
T
G
K
K
I
Site 3
T25
K
Q
C
T
R
V
T
T
L
T
G
K
K
I
I
Site 4
T27
C
T
R
V
T
T
L
T
G
K
K
I
I
E
T
Site 5
S49
V
V
E
E
V
E
P
S
S
G
G
G
C
G
Y
Site 6
S50
V
E
E
V
E
P
S
S
G
G
G
C
G
Y
V
Site 7
Y56
S
S
G
G
G
C
G
Y
V
Q
D
L
S
S
D
Site 8
S77
K
P
W
L
L
L
G
S
Q
D
A
A
H
D
L
Site 9
T86
D
A
A
H
D
L
D
T
L
K
K
N
K
V
T
Site 10
S108
G
V
E
N
A
F
L
S
D
F
T
Y
K
S
I
Site 11
S116
D
F
T
Y
K
S
I
S
I
L
D
L
P
E
T
Site 12
S127
L
P
E
T
N
I
L
S
Y
F
P
E
C
F
E
Site 13
Y128
P
E
T
N
I
L
S
Y
F
P
E
C
F
E
F
Site 14
S172
L
M
N
S
E
Q
T
S
F
T
S
A
F
S
L
Site 15
T174
N
S
E
Q
T
S
F
T
S
A
F
S
L
V
K
Site 16
S178
T
S
F
T
S
A
F
S
L
V
K
N
A
R
P
Site 17
S186
L
V
K
N
A
R
P
S
I
C
P
N
S
G
F
Site 18
S191
R
P
S
I
C
P
N
S
G
F
M
E
Q
L
R
Site 19
T199
G
F
M
E
Q
L
R
T
Y
Q
E
G
K
E
S
Site 20
Y200
F
M
E
Q
L
R
T
Y
Q
E
G
K
E
S
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation