KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
NOC3L
Full Name:
Nucleolar complex protein 3 homolog
Alias:
AD24; C10orf117; FAD24; FLJ12820; NOC3 protein homologue; NOC3-like protein; Nucleolar complex associated 3; Nucleolar complex associated 3 homolog
Type:
Mass (Da):
92548
Number AA:
800
UniProt ID:
Q8WTT2
International Prot ID:
IPI00102815
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016607
GO:0005730
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
R
N
K
K
Q
I
P
S
F
R
K
L
I
K
T
Site 2
T19
S
F
R
K
L
I
K
T
S
K
V
K
L
E
N
Site 3
S37
N
K
Q
F
K
Q
Q
S
T
L
K
K
Y
R
K
Site 4
S108
K
D
L
G
Q
R
V
S
F
L
T
R
D
L
S
Site 5
T111
G
Q
R
V
S
F
L
T
R
D
L
S
S
S
E
Site 6
S115
S
F
L
T
R
D
L
S
S
S
E
P
V
H
A
Site 7
S116
F
L
T
R
D
L
S
S
S
E
P
V
H
A
K
Site 8
S117
L
T
R
D
L
S
S
S
E
P
V
H
A
K
K
Site 9
Y134
H
E
R
I
I
D
K
Y
E
K
I
P
R
T
L
Site 10
T140
K
Y
E
K
I
P
R
T
L
Q
T
A
P
E
K
Site 11
S159
L
L
P
I
K
D
K
S
G
I
I
P
Q
T
R
Site 12
T165
K
S
G
I
I
P
Q
T
R
E
K
P
V
T
D
Site 13
T171
Q
T
R
E
K
P
V
T
D
S
N
K
D
E
E
Site 14
S173
R
E
K
P
V
T
D
S
N
K
D
E
E
D
Q
Site 15
S227
A
L
A
S
A
I
L
S
D
P
E
N
N
I
K
Site 16
S241
K
K
L
K
E
L
R
S
M
L
M
E
Q
D
P
Site 17
T270
M
E
L
F
K
D
I
T
P
S
Y
K
I
R
P
Site 18
S272
L
F
K
D
I
T
P
S
Y
K
I
R
P
L
T
Site 19
Y273
F
K
D
I
T
P
S
Y
K
I
R
P
L
T
E
Site 20
T279
S
Y
K
I
R
P
L
T
E
A
E
K
S
T
K
Site 21
S284
P
L
T
E
A
E
K
S
T
K
T
R
K
E
T
Site 22
T291
S
T
K
T
R
K
E
T
Q
K
L
R
E
F
E
Site 23
S303
E
F
E
E
G
L
V
S
Q
Y
K
F
Y
L
E
Site 24
Y308
L
V
S
Q
Y
K
F
Y
L
E
N
L
E
Q
M
Site 25
S327
K
Q
R
K
L
K
K
S
N
V
V
S
L
K
A
Site 26
S331
L
K
K
S
N
V
V
S
L
K
A
Y
K
G
L
Site 27
S398
Q
D
K
L
G
Q
A
S
L
G
V
I
K
V
I
Site 28
Y414
G
F
V
K
G
R
N
Y
E
V
R
P
E
M
L
Site 29
T449
N
K
P
K
K
F
M
T
F
K
E
K
R
K
S
Site 30
S456
T
F
K
E
K
R
K
S
L
S
R
M
Q
R
K
Site 31
S458
K
E
K
R
K
S
L
S
R
M
Q
R
K
W
K
Site 32
S481
E
L
R
E
A
E
A
S
E
S
T
E
K
K
L
Site 33
S483
R
E
A
E
A
S
E
S
T
E
K
K
L
K
L
Site 34
S551
L
I
E
S
G
D
L
S
Y
Q
E
S
L
H
C
Site 35
Y552
I
E
S
G
D
L
S
Y
Q
E
S
L
H
C
V
Site 36
S555
G
D
L
S
Y
Q
E
S
L
H
C
V
Q
T
A
Site 37
Y585
L
K
F
Y
T
H
L
Y
K
T
L
F
K
L
H
Site 38
T587
F
Y
T
H
L
Y
K
T
L
F
K
L
H
A
G
Site 39
T612
Q
C
L
D
V
M
L
T
K
R
R
K
Q
V
S
Site 40
S619
T
K
R
R
K
Q
V
S
Q
Q
R
A
L
A
F
Site 41
T659
L
M
H
T
F
P
K
T
D
L
L
L
D
S
E
Site 42
S665
K
T
D
L
L
L
D
S
E
S
Q
G
S
G
V
Site 43
S670
L
D
S
E
S
Q
G
S
G
V
F
L
P
E
L
Site 44
Y682
P
E
L
D
E
P
E
Y
C
N
A
Q
N
T
A
Site 45
Y700
L
H
A
L
R
R
H
Y
H
P
I
V
Q
R
F
Site 46
S717
H
L
I
A
G
A
P
S
E
G
S
G
A
L
K
Site 47
S728
G
A
L
K
P
E
L
S
R
R
S
A
T
E
L
Site 48
S731
K
P
E
L
S
R
R
S
A
T
E
L
F
E
A
Site 49
T733
E
L
S
R
R
S
A
T
E
L
F
E
A
Y
S
Site 50
T745
A
Y
S
M
A
E
M
T
F
N
P
P
V
E
S
Site 51
S752
T
F
N
P
P
V
E
S
S
N
P
K
I
K
G
Site 52
S753
F
N
P
P
V
E
S
S
N
P
K
I
K
G
K
Site 53
S766
G
K
F
L
Q
G
D
S
F
L
N
E
D
L
N
Site 54
Y779
L
N
Q
L
I
K
R
Y
S
S
E
V
A
T
E
Site 55
S780
N
Q
L
I
K
R
Y
S
S
E
V
A
T
E
S
Site 56
S781
Q
L
I
K
R
Y
S
S
E
V
A
T
E
S
P
Site 57
T785
R
Y
S
S
E
V
A
T
E
S
P
L
D
F
T
Site 58
S787
S
S
E
V
A
T
E
S
P
L
D
F
T
K
Y
Site 59
T792
T
E
S
P
L
D
F
T
K
Y
L
K
T
S
L
Site 60
Y794
S
P
L
D
F
T
K
Y
L
K
T
S
L
H
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation