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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TUSC4
Full Name:
Nitrogen permease regulator 2-like protein
Alias:
Gene 21 protein;Tumor suppressor candidate 4
Type:
Mass (Da):
43658
Number AA:
380
UniProt ID:
Q8WTW4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T18
F
F
S
E
F
H
P
T
L
G
P
K
I
T
Y
Site 2
Y25
T
L
G
P
K
I
T
Y
Q
V
P
E
D
F
I
Site 3
S33
Q
V
P
E
D
F
I
S
R
E
L
F
D
T
V
Site 4
T56
E
L
Q
N
K
L
I
T
V
T
A
M
E
K
K
Site 5
Y76
V
C
I
E
H
K
K
Y
S
R
N
A
L
L
F
Site 6
T110
K
K
L
A
G
Y
L
T
T
L
E
L
E
S
S
Site 7
S116
L
T
T
L
E
L
E
S
S
F
V
S
M
E
E
Site 8
S117
T
T
L
E
L
E
S
S
F
V
S
M
E
E
S
Site 9
S120
E
L
E
S
S
F
V
S
M
E
E
S
K
Q
K
Site 10
S124
S
F
V
S
M
E
E
S
K
Q
K
L
V
P
I
Site 11
T146
L
N
A
S
G
R
C
T
L
P
I
D
E
S
N
Site 12
Y172
D
P
P
V
A
Q
E
Y
D
V
P
V
F
T
K
Site 13
T192
F
N
S
Q
W
D
L
T
T
Q
Q
I
L
P
Y
Site 14
Y199
T
T
Q
Q
I
L
P
Y
I
D
G
F
R
H
I
Site 15
T248
Y
S
N
V
Y
C
P
T
P
K
V
Q
D
L
V
Site 16
S259
Q
D
L
V
D
D
K
S
L
Q
E
A
C
L
S
Site 17
S266
S
L
Q
E
A
C
L
S
Y
V
T
K
Q
G
H
Site 18
Y267
L
Q
E
A
C
L
S
Y
V
T
K
Q
G
H
K
Site 19
S277
K
Q
G
H
K
R
A
S
L
R
D
V
F
Q
L
Site 20
S289
F
Q
L
Y
C
S
L
S
P
G
T
T
V
R
D
Site 21
T293
C
S
L
S
P
G
T
T
V
R
D
L
I
G
R
Site 22
Y329
L
I
R
R
L
Q
K
Y
P
V
R
V
T
R
E
Site 23
T334
Q
K
Y
P
V
R
V
T
R
E
E
Q
S
H
P
Site 24
Y345
Q
S
H
P
A
R
L
Y
T
G
C
H
S
Y
D
Site 25
T346
S
H
P
A
R
L
Y
T
G
C
H
S
Y
D
E
Site 26
Y351
L
Y
T
G
C
H
S
Y
D
E
I
C
C
K
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation