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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PYROXD1
Full Name:
Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1
Alias:
Type:
Mass (Da):
55774
Number AA:
500
UniProt ID:
Q8WU10
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0009055
GO:0016491
PhosphoSite+
KinaseNET
Biological Process:
GO:0055114
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T31
T
C
A
E
Q
L
A
T
H
F
P
S
E
D
I
Site 2
S69
E
F
D
V
E
E
Q
S
S
T
M
L
G
K
R
Site 3
T71
D
V
E
E
Q
S
S
T
M
L
G
K
R
F
P
Site 4
S92
S
G
V
K
Q
L
K
S
E
E
H
C
I
V
T
Site 5
Y107
E
D
G
N
Q
H
V
Y
K
K
L
C
L
C
A
Site 6
T134
Y
V
L
G
I
R
D
T
D
S
A
Q
E
F
Q
Site 7
S136
L
G
I
R
D
T
D
S
A
Q
E
F
Q
K
Q
Site 8
T183
K
D
K
A
I
G
N
T
F
F
D
A
G
A
A
Site 9
S202
S
K
L
I
A
E
K
S
E
A
K
I
A
H
K
Site 10
Y213
I
A
H
K
R
T
R
Y
T
T
E
G
R
K
K
Site 11
T214
A
H
K
R
T
R
Y
T
T
E
G
R
K
K
E
Site 12
T215
H
K
R
T
R
Y
T
T
E
G
R
K
K
E
A
Site 13
S226
K
K
E
A
R
S
K
S
K
A
D
N
V
G
S
Site 14
T248
E
G
L
N
L
K
G
T
K
E
F
S
H
K
I
Site 15
Y267
M
C
E
V
K
K
I
Y
L
Q
D
E
F
R
I
Site 16
S279
F
R
I
L
K
K
K
S
F
T
F
P
R
D
H
Site 17
T281
I
L
K
K
K
S
F
T
F
P
R
D
H
K
S
Site 18
S288
T
F
P
R
D
H
K
S
V
T
A
D
T
E
M
Site 19
Y299
D
T
E
M
W
P
V
Y
V
E
L
T
N
E
K
Site 20
Y308
E
L
T
N
E
K
I
Y
G
C
D
F
I
V
S
Site 21
S331
E
P
F
L
H
G
N
S
F
D
L
G
E
D
G
Site 22
Y354
H
T
S
L
P
D
I
Y
A
A
G
D
I
C
T
Site 23
T361
Y
A
A
G
D
I
C
T
T
S
W
Q
L
S
P
Site 24
S398
A
A
A
S
S
G
D
S
I
D
M
D
F
S
F
Site 25
S432
Y
N
A
Q
G
L
G
S
D
H
E
L
M
L
R
Site 26
T441
H
E
L
M
L
R
C
T
K
G
R
E
Y
I
K
Site 27
Y446
R
C
T
K
G
R
E
Y
I
K
V
V
M
Q
N
Site 28
T470
G
E
T
D
L
E
E
T
F
E
N
L
I
L
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation