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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SCFD2
Full Name:
Sec1 family domain-containing protein 2
Alias:
FLJ39514; sec1 family domain containing 2; STXBP1L1; syntaxin-binding protein 1-like 1
Type:
Mass (Da):
75130
Number AA:
UniProt ID:
Q8WU76
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0015031
GO:0006904
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
S
A
S
G
V
L
S
F
T
Q
Q
G
W
E
Site 2
S189
Q
D
V
H
L
L
N
S
A
R
P
D
K
R
K
Site 3
S199
P
D
K
R
K
L
G
S
L
G
D
V
D
S
T
Site 4
S205
G
S
L
G
D
V
D
S
T
T
L
T
P
E
L
Site 5
T262
P
A
K
N
R
K
K
T
A
A
G
R
A
S
V
Site 6
T279
V
D
R
T
L
D
L
T
G
A
V
G
H
H
G
Site 7
Y324
L
H
T
E
E
E
N
Y
N
V
V
A
P
G
C
Site 8
S335
A
P
G
C
L
S
Q
S
S
D
T
T
A
K
A
Site 9
S336
P
G
C
L
S
Q
S
S
D
T
T
A
K
A
L
Site 10
T339
L
S
Q
S
S
D
T
T
A
K
A
L
W
E
A
Site 11
S368
R
H
L
V
E
A
A
S
R
E
N
L
P
I
K
Site 12
S377
E
N
L
P
I
K
M
S
M
G
R
V
T
P
G
Site 13
T382
K
M
S
M
G
R
V
T
P
G
Q
L
M
S
Y
Site 14
S388
V
T
P
G
Q
L
M
S
Y
I
Q
L
F
K
N
Site 15
Y389
T
P
G
Q
L
M
S
Y
I
Q
L
F
K
N
N
Site 16
T416
L
G
L
A
T
A
Q
T
L
K
H
P
Q
T
A
Site 17
T459
L
P
M
I
K
P
V
T
Q
R
T
N
E
D
Y
Site 18
Y466
T
Q
R
T
N
E
D
Y
S
P
E
E
L
L
I
Site 19
S467
Q
R
T
N
E
D
Y
S
P
E
E
L
L
I
L
Site 20
T486
Y
S
V
T
G
E
L
T
V
D
K
D
L
C
E
Site 21
T520
S
P
L
L
Q
K
I
T
D
W
D
S
S
I
N
Site 22
T529
W
D
S
S
I
N
L
T
F
H
K
S
K
I
A
Site 23
S552
R
D
I
A
G
A
R
S
L
L
K
Q
F
K
S
Site 24
S559
S
L
L
K
Q
F
K
S
V
Y
V
P
G
N
H
Site 25
Y561
L
K
Q
F
K
S
V
Y
V
P
G
N
H
T
H
Site 26
S571
G
N
H
T
H
Q
A
S
Y
K
P
L
L
K
Q
Site 27
S591
F
H
P
E
R
P
D
S
V
D
I
E
H
M
S
Site 28
S599
V
D
I
E
H
M
S
S
G
L
T
D
L
L
K
Site 29
T602
E
H
M
S
S
G
L
T
D
L
L
K
T
G
F
Site 30
S621
K
V
S
R
P
H
P
S
D
Y
P
L
L
I
L
Site 31
S648
M
V
K
D
L
V
A
S
L
K
P
G
T
Q
V
Site 32
T653
V
A
S
L
K
P
G
T
Q
V
I
V
L
S
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation