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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM172A
Full Name:
Protein FAM172A
Alias:
Type:
Mass (Da):
47972
Number AA:
416
UniProt ID:
Q8WUF8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T31
G
P
D
E
K
E
K
T
T
A
L
K
D
L
L
Site 2
T59
P
P
L
D
F
P
D
T
L
E
G
F
E
Y
A
Site 3
Y65
D
T
L
E
G
F
E
Y
A
F
N
E
K
G
Q
Site 4
T78
G
Q
L
R
H
I
K
T
G
E
P
F
V
F
N
Site 5
Y86
G
E
P
F
V
F
N
Y
R
E
D
L
H
R
W
Site 6
Y98
H
R
W
N
Q
K
R
Y
E
A
L
G
E
I
I
Site 7
T129
V
S
I
P
V
D
A
T
E
S
E
P
K
S
F
Site 8
S131
I
P
V
D
A
T
E
S
E
P
K
S
F
I
F
Site 9
S135
A
T
E
S
E
P
K
S
F
I
F
M
S
E
D
Site 10
S140
P
K
S
F
I
F
M
S
E
D
A
L
T
N
P
Site 11
T145
F
M
S
E
D
A
L
T
N
P
Q
K
L
M
V
Site 12
T179
N
E
D
L
D
S
G
T
Q
I
P
F
I
K
R
Site 13
Y203
V
L
N
P
N
E
N
Y
I
E
V
E
K
P
K
Site 14
S215
K
P
K
I
H
V
Q
S
S
S
D
S
S
D
E
Site 15
S216
P
K
I
H
V
Q
S
S
S
D
S
S
D
E
P
Site 16
S217
K
I
H
V
Q
S
S
S
D
S
S
D
E
P
A
Site 17
S219
H
V
Q
S
S
S
D
S
S
D
E
P
A
E
K
Site 18
S220
V
Q
S
S
S
D
S
S
D
E
P
A
E
K
R
Site 19
S234
R
E
R
K
D
K
V
S
K
E
T
K
K
R
R
Site 20
Y244
T
K
K
R
R
D
F
Y
E
K
Y
R
N
P
Q
Site 21
Y247
R
R
D
F
Y
E
K
Y
R
N
P
Q
R
E
K
Site 22
Y260
E
K
E
M
M
Q
L
Y
I
R
E
N
G
S
P
Site 23
S266
L
Y
I
R
E
N
G
S
P
E
E
H
A
I
Y
Site 24
Y273
S
P
E
E
H
A
I
Y
V
W
D
H
F
I
A
Site 25
S350
C
C
N
W
V
S
S
S
E
P
L
D
T
S
V
Site 26
T355
S
S
S
E
P
L
D
T
S
V
E
S
M
L
P
Site 27
S356
S
S
E
P
L
D
T
S
V
E
S
M
L
P
D
Site 28
S368
L
P
D
C
P
R
V
S
A
G
T
D
R
H
E
Site 29
T371
C
P
R
V
S
A
G
T
D
R
H
E
L
T
S
Site 30
T377
G
T
D
R
H
E
L
T
S
W
K
S
F
P
S
Site 31
S378
T
D
R
H
E
L
T
S
W
K
S
F
P
S
I
Site 32
S381
H
E
L
T
S
W
K
S
F
P
S
I
F
K
F
Site 33
S384
T
S
W
K
S
F
P
S
I
F
K
F
F
T
E
Site 34
S393
F
K
F
F
T
E
A
S
E
A
K
T
S
S
L
Site 35
T397
T
E
A
S
E
A
K
T
S
S
L
K
P
A
V
Site 36
S399
A
S
E
A
K
T
S
S
L
K
P
A
V
T
R
Site 37
T405
S
S
L
K
P
A
V
T
R
R
S
H
R
I
K
Site 38
S408
K
P
A
V
T
R
R
S
H
R
I
K
H
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation