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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TGFBRAP1
Full Name:
Transforming growth factor-beta receptor-associated protein 1
Alias:
Type:
Mass (Da):
97158
Number AA:
860
UniProt ID:
Q8WUH2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y38
E
C
C
G
R
D
L
Y
V
G
T
N
D
C
F
Site 2
Y47
G
T
N
D
C
F
V
Y
H
F
L
L
E
E
R
Site 3
S112
L
N
L
E
P
V
P
S
G
A
R
I
K
G
A
Site 4
T121
A
R
I
K
G
A
A
T
F
A
L
N
E
N
P
Site 5
S130
A
L
N
E
N
P
V
S
G
D
P
F
C
V
E
Site 6
Y193
T
Q
Y
I
I
H
N
Y
S
T
G
V
S
Q
D
Site 7
Y204
V
S
Q
D
L
F
P
Y
C
S
E
E
R
P
P
Site 8
S206
Q
D
L
F
P
Y
C
S
E
E
R
P
P
I
V
Site 9
T269
A
L
D
D
E
F
I
T
V
H
S
M
L
D
Q
Site 10
S323
Q
I
Q
D
L
L
A
S
R
R
V
E
E
A
L
Site 11
Y349
K
E
K
F
Q
V
M
Y
R
R
I
L
Q
Q
A
Site 12
S375
E
A
K
E
L
F
R
S
G
Q
L
D
V
R
E
Site 13
T393
L
Y
P
F
L
L
P
T
S
S
S
F
T
R
S
Site 14
S394
Y
P
F
L
L
P
T
S
S
S
F
T
R
S
H
Site 15
S395
P
F
L
L
P
T
S
S
S
F
T
R
S
H
P
Site 16
S396
F
L
L
P
T
S
S
S
F
T
R
S
H
P
P
Site 17
T398
L
P
T
S
S
S
F
T
R
S
H
P
P
L
H
Site 18
S400
T
S
S
S
F
T
R
S
H
P
P
L
H
E
Y
Site 19
Y407
S
H
P
P
L
H
E
Y
A
D
L
N
Q
L
T
Site 20
S430
K
C
K
R
F
L
M
S
Y
L
N
E
V
R
S
Site 21
Y431
C
K
R
F
L
M
S
Y
L
N
E
V
R
S
T
Site 22
S437
S
Y
L
N
E
V
R
S
T
E
V
A
N
G
Y
Site 23
T438
Y
L
N
E
V
R
S
T
E
V
A
N
G
Y
K
Site 24
T450
G
Y
K
E
D
I
D
T
A
L
L
K
L
Y
A
Site 25
Y489
W
L
E
K
H
K
K
Y
F
A
L
G
L
L
Y
Site 26
S520
V
N
G
D
V
Q
D
S
T
R
S
D
L
Y
E
Site 27
T521
N
G
D
V
Q
D
S
T
R
S
D
L
Y
E
Y
Site 28
Y526
D
S
T
R
S
D
L
Y
E
Y
I
V
D
F
L
Site 29
Y528
T
R
S
D
L
Y
E
Y
I
V
D
F
L
T
Y
Site 30
S553
A
D
W
V
L
Q
K
S
E
E
V
G
V
Q
V
Site 31
S573
L
D
E
Q
Q
K
N
S
F
N
P
D
D
I
I
Site 32
Y593
Y
P
K
A
L
V
K
Y
L
E
H
L
V
I
D
Site 33
Y608
K
R
L
Q
K
E
E
Y
H
T
H
L
A
V
L
Site 34
T610
L
Q
K
E
E
Y
H
T
H
L
A
V
L
Y
L
Site 35
S626
E
V
L
L
Q
R
A
S
A
S
G
K
G
A
E
Site 36
T637
K
G
A
E
A
T
E
T
Q
A
K
L
R
R
L
Site 37
S648
L
R
R
L
L
Q
K
S
D
L
Y
R
V
H
F
Site 38
Y699
D
F
A
A
A
E
D
Y
C
L
W
C
S
E
G
Site 39
T746
D
L
L
N
R
H
A
T
E
F
D
A
A
Q
V
Site 40
S777
L
M
G
A
M
R
D
S
I
H
A
R
R
T
M
Site 41
T783
D
S
I
H
A
R
R
T
M
Q
V
A
L
G
L
Site 42
Y798
A
R
S
E
N
L
I
Y
T
Y
D
K
M
K
L
Site 43
Y800
S
E
N
L
I
Y
T
Y
D
K
M
K
L
K
G
Site 44
S808
D
K
M
K
L
K
G
S
S
I
Q
L
S
D
K
Site 45
S809
K
M
K
L
K
G
S
S
I
Q
L
S
D
K
K
Site 46
S813
K
G
S
S
I
Q
L
S
D
K
K
L
C
Q
I
Site 47
T841
P
N
G
G
L
V
H
T
H
C
A
A
S
R
H
Site 48
S846
V
H
T
H
C
A
A
S
R
H
T
N
P
S
S
Site 49
T849
H
C
A
A
S
R
H
T
N
P
S
S
S
S
P
Site 50
S852
A
S
R
H
T
N
P
S
S
S
S
P
G
T
R
Site 51
S853
S
R
H
T
N
P
S
S
S
S
P
G
T
R
T
Site 52
S854
R
H
T
N
P
S
S
S
S
P
G
T
R
T
_
Site 53
S855
H
T
N
P
S
S
S
S
P
G
T
R
T
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation