PhosphoNET

           
Protein Info 
   
Short Name:  STYX
Full Name:  Serine/threonine/tyrosine-interacting protein
Alias:  Protein tyrosine phosphatase-like protein
Type: 
Mass (Da):  25492
Number AA:  223
UniProt ID:  Q8WUJ0
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y23EDAEEWTYPMRREMQ
Site 2Y41PGLFLGPYSSAMKSK
Site 3S43LFLGPYSSAMKSKLP
Site 4S47PYSSAMKSKLPVLQK
Site 5S109TKEFIDGSLQMGGKV
Site 6Y134SAAFVIAYIMETFGM
Site 7Y143METFGMKYRDAFAYV
Site 8Y149KYRDAFAYVQERRFC
Site 9Y170FVHQLQEYEAIYLAK
Site 10S184KLTIQMMSPLQIERS
Site 11S191SPLQIERSLSVHSGT
Site 12S193LQIERSLSVHSGTTG
Site 13S201VHSGTTGSLKRTHEE
Site 14T205TTGSLKRTHEEEDDF
Site 15T214EEEDDFGTMQVATAQ
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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